Ligand binding to symmetrical FeZn hybrids of variants of human HbA with modifications in the α1-β2 interface

Biochemistry

Volumn 43, Issue 24, 2004, Pages 7843-7850

  Hui, Hilda L ^a   Kwiatkowski, Laura D ^a   Karasik, Ellen ^a   Colby, Judith E ^a   Noble, Robert W ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; CARBON MONOXIDE; DISSOCIATION; HEMOGLOBIN; INTERFACES (MATERIALS); OXYGEN; PH EFFECTS; PHOSPHATES; REACTION KINETICS;

EQUILIBRIUM CONSTANTS; INOSITOL HEXAPHOSPHATES (IHP);

BIOCHEMISTRY;

CARBON MONOXIDE; DEOXYHEMOGLOBIN; HEME DERIVATIVE; HEMOGLOBIN A; HEMOGLOBIN A ALPHA1; HEMOGLOBIN A BETA2; IRON COMPLEX; LIGAND; OXYGEN; PHYTIC ACID; PROTOPORPHYRIN; PROTOPORPHYRIN ZINC; TETRAMER; UNCLASSIFIED DRUG; ZINC COMPLEX;

ARTICLE; BINDING SITE; DISSOCIATION CONSTANT; GEOMETRY; HUMAN; HYBRID; LIGAND BINDING; OXYGEN AFFINITY; PH; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN MODIFICATION; PROTEIN STRUCTURE;

CARBON MONOXIDE; HEMOGLOBIN A; HUMANS; IRON; KINETICS; LIGANDS; OXYGEN; PROTEIN BINDING; ZINC;

EID: 2942715197     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi030263g     Document Type: Article

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