Intravenous nicorandil can reduce the occurence of venticular fibrillation and QT dispersion in patients with successful coronary angioplasty in acute myocardial infarction

Canadian Journal of Cardiology

Volumn 20, Issue 6, 2004, Pages 625-629

  Ueda, Hiroyasu ^a   Nakayama, Yasunori ^a   Tsumura, Kei ^b   Yoshimaru, Kiyomichi ^a   Hayashi, Tomoshige ^b   Yoshikawa, Junichi ^b  

^a Ishikiriseiki Hospital   (Japan)

^b OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Electrocardiography; Myocardial infarction; Ventricular fibrillation

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM ANTAGONIST; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HEPARIN; NICORANDIL; NITRIC ACID DERIVATIVE; ANTIARRHYTHMIC AGENT;

ACUTE HEART INFARCTION; ADULT; ARTICLE; COHORT ANALYSIS; CONTINUOUS INFUSION; CONTROLLED STUDY; FEMALE; HEART VENTRICLE FIBRILLATION; HOSPITAL ADMISSION; HUMAN; MAJOR CLINICAL STUDY; MALE; POSTOPERATIVE CARE; QT DISPERSION; TRANSLUMINAL CORONARY ANGIOPLASTY; TREATMENT OUTCOME; ANGIOCARDIOGRAPHY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; ELECTROCARDIOGRAPHY; HEART INFARCTION; INTRAVENOUS DRUG ADMINISTRATION; MIDDLE AGED; PATHOPHYSIOLOGY;

ANGIOPLASTY, TRANSLUMINAL, PERCUTANEOUS CORONARY; ANTI-ARRHYTHMIA AGENTS; COHORT STUDIES; CORONARY ANGIOGRAPHY; ELECTROCARDIOGRAPHY; FEMALE; HUMANS; INJECTIONS, INTRAVENOUS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; NICORANDIL; VENTRICULAR FIBRILLATION;

EID: 2942711458     PISSN: 0828282X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Hii JT, Wyse DG, Gillis AM, Duff HJ, Solylo MA, Mitchell LB. Precordial QT interval dispersion as a maker of torsade de pointes. Disparate effects of class Ia antiarrhythmic drugs and amiodarone. Circulation 1992;86:1376-82.
2. Antzelevitch C, Shimizu W, Yan GX, Sicouri S. Cellular basis for QT dispersion. J Electrocardiol 1998;30(Suppl):168-75.
3. Higham PD, Furniss SS, Campbell RW. QT dispersion and components of the QT interval in ischemia and infarction. Br Heart J 1995;73:32-6.
4. Yi G, Elliott P, McKenna WJ, et al. QT dispersion and risk factors for sudden cardiac death in patients with hypertrophic cardiomyopathy. Am J Cardiol 1998;82:1514-9.
5. Taira N. Nicorandil as a hybrid between nitrates and potassium channel activators. Am J Cardiol 1989;63:18J-24J.
6. Ito H, Taniyama Y, Iwakura K, et al. Intravenous nicorandil can preserve microvascular integrity and myocardial viability in patients with reperfused anterior wall myocardial infarction. J Am Coll Cardiol 1999;33:654-60.
7. Uehata A, Matsuguchi T, Bittl JA, et al. Accuracy of electronic digital calipers compared with quantitative angiography in measuring coronary arterial diameter. Circulation 1993;88:1724-9.
8. Taran LM, Szilagyi N. The duration of the electrical systole (QT) in acute rheumatic carditis in children. Am Heart J 1947;33:14-26.
9. Kobayashi Y, Miyata A, Tanno K, Kikushima S, Baba T, Katagiri T. Effect of nicorandil, a potassium channel opener, on idiopathic ventricular tachycardia. J Am Coll Cardiol 1998;32:1377-83.
10. Mizunuma T, Nithipatikom K, Gross GJ. Effects of nicorandil and glyceryl trinitrate on infarct size, adenosine release and neutrophil infiltration in the dog. Cardiovasc Res 1995;29:482-9.
11. Galie N, Guarnieri C, Ussia GP, et al. Limitation of myocardial infarct size by nicorandil after sustained ischemia in pigs. J Cardiovasc Pharmacol 1995;26:477-84.
12. Patel DJ, Purcell HJ, Fox KM. Cardioprotection by opening of the K(ATP) channel in unstable angina: Is this a clinical manifestation of myocardial preconditioning? Results of a randomized study with nicorandil. CESAR 2 investigation. Clinical European studies in angina and revascularization. Eur Heart J 1999;20:51-7.
13. Sato T, Sasaki N, O'Rourke B, Marban E. Nicorandil, a potent cardioprotective agent, acts by opening mitochondrial ATP-dependent potassium channels. J Am Coll Cardiol 2000;35:514-8.
14. Murray A, McLaughlin NB, Campbell RW. Measuring QT dispersion: Man versus machine. Heart 1997;77:539-42.
15. Gang Y, Guo XH, Crook R, Hnatkova K, Camm AJ, Malik M. Computerised measurements of QT dispersion in healthy subjects. Heart 1998;80:459-66.
16. Dabrowski A, Kramarz E, Piotrowicz R, Kubik L. Predictive power of increased QT dispersion in ventricular extrasystoles and in sinus beats for risk stratification after myocardial infarction. Circulation 2000;101:1693-7.