Regulation of T-cell death-associated gene 51 (TDAG51) expression in human T-cells

Cell Death and Differentiation

Volumn 11, Issue 6, 2004, Pages 674-684

  Oberg, H H ^a   Sipos, B ^a   Kalthoff, H ^a   Janssen, O ^a   Kabelitz, D ^a  

^a UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

Author keywords

Apoptosis; Fas expression; T cell receptor; T lymphocytes

Indexed keywords

2 [1 (3 DIMETHYLAMINOPROPYL) 5 METHOXY 1H INDOL 3 YL] 3 (1H INDOL 3 YL)MALEIMIDE; CD3 ANTIGEN; FAS ANTIGEN; GENE PRODUCT; IONOMYCIN; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PHORBOL ESTER; PROTEIN KINASE C INHIBITOR; T CELL DEATH ASSOCIATED GENE 51 PROTEIN; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CELL DEATH; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE INDUCTION; GENE OVEREXPRESSION; GROWTH INHIBITION; HUMAN; HUMAN CELL; HYBRIDOMA; LEUKEMIA CELL LINE; LYMPHOCYTE CLONE; LYMPHOID CELL LINE; PRIORITY JOURNAL; T LYMPHOCYTE;

MURINAE;

EID: 2942702046     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4401407     Document Type: Article

References (31)

1. Kabelitz D, Pohl T and Pechhold K (1993) Activation-induced cell death (apoptosis) of mature peripheral T lymphocytes. Immunol. Today 14: 338-339
2. Dhein J, Walczak H, Baeumler C, Debatin KM and Krammer PH (1995) Autocrine T-cell suicide mediated by APO-1/(Fas/CD95). Nature 373: 438-441
3. Brunner T, Mogil RJ, LaFace D, Yoo NJ, Mahboubi A, Echeverri F, Martin SJ, Force WR, Lynch DH, Ware CF and Green DR (1995) Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas. Nature 373: 441-444
4. Ju ST, Panka DJ, Cui H, Ettinger R, el-Khatib M, Sherr DH, Stanger BZ and Marshak-Rothstein A (1995) Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation. Nature 373: 444-448
5. Wesselborg S, Janssen O and Kabelitz D (1993) Induction of activation-driven death (apoptosis) in activated but not resting peripheral blood T cells. J. Immunol. 150: 4338-4345
6. short correlates with resistance toward CD95-mediated apoptosis by blocking death-inducing signaling complex activity. J. Immunol. 165: 6293-6300
7. short and reduction of activation-induced cell death in CD28-costimulated human T cells. Eur. J. Immunol. 30: 2765-2774
8. L modulates T-cell receptor-induced proliferation but not activation-induced cell death of lymphocytes. Mol. Cell. Biol. 22: 5419-5433
9. Thome M and Tschopp J (2001) Regulation of lymphocyte proliferation and death by FLIP. Nat. Rev. Immunol. 1: 50-58
10. Schmitz I, Krueger A, Baumann S, Schulze-Bergkamen H, Krammer PH and Kirchhoff S (2003) An IL-2-dependent switch between CD95 signaling pathways sensitizes primary human T cells toward CD95-mediated activation-induced cell death. J. Immunol. 171: 2930-2936
11. Peter ME and Krammer PH (2003) The CD95(APO-1/Fas) DISC and beyond. Cell Death Differ 10: 26-35
12. Park CG, Lee SY, Kandala G, Lee SY and Choi Y (1996) A novel gene product that couples TCR signaling to Fas(CD95) expression in activation-induced cell death. Immunity 4: 583-591
13. Rho J, Gong S, Kim N and Choi Y (2001) TDAG51 is not essential for Fas/CD95 regulation and apoptosis in vivo. Mol. Cell. Biol. 21: 8365-8370
14. Gomes I, Xiong W, Miki T and Rosner MR (1999) A proline- and glutamine-rich protein promotes apoptosis in neuronal cells. J. Neurochem. 73: 612-622
15. Neef R, Kuske MA, Pröls E and Johnson JP (2002) Identification of the human PHLDA1/TDAG51 gene: down-regulation in metastatic melanoma contributes to apoptosis resistance and growth deregulation. Cancer Res. 62: 5920-5929
16. Wang R, Zhang L, Yin D, Mufson RA and Shi Y (1998) Protein kinase C regulates Fas (CD95/Apo-1) expression. J. Immunol. 161: 2201-2207
17. Oberg HH, Lengl-Janßen B, Kabelitz D and Janssen O (1997) Activation-induced T cell death: resistance or susceptibility correlate with cell surface Fas ligand expression and T helper phenotype. Cell. Immunol. 181: 93-100
18. Qian N, Frank D, O'Keefe D, Dao D, Zhao L, Yuan L, Wang Q, Keating M, Walsh C and Tycko B (1997) The IPL gene on chromosome 11p15.5 is imprinted in humans and mice and is similar to TDAG51, implicated in Fas expression and apoptosis. Hum. Mol. Genet. 6: 2021-2029
19. Hu RJ, Maxwell PL, Connors TD, Johnson LA, Burn TC, Su K, Landes GM and Feinberg AP (1997) A 2.5-Mb transcript map of a tumor-suppressing subchromosomal transferable fragment from 11p15.5, and isolation and sequence analysis of three novel genes. Genomics 46: 9-17
20. Lee MP and Feinberg AP (1998) Genomic imprinting of a human apoptosis homologue, TSSC3. Cancer Res. 58: 1052-1056
21. Frank D, Mendelsohn CL, Ciccone E, Svensson K, Ohlsson R and Tycko BA (1999) A novel pleckstrin homology-related gene family defined by IpI/Tssc3, TDAG51, and Tih1: tissue-specific expression, chromosomal location, and parental imprinting. Mamm. Genome 10: 1150-1159
22. Hossain GS, van Thienen JV, Werstuck GH, Zhou J, Sood SK, Dickhout JG, de Koning ABL, Tang D, Wu D, Falk E, Poddar R, Jacobsen DW, Zhang K, Kaufman RJ and Austin RC (2003) TDAG51 is induced by homocysteine, promotes detachment-mediated programmed cell death, and contributes to the development of atherosclerosis in hyperhomocysteinemia. J. Biol. Chem. 278: 30317-30327
23. Hinz T, Flindt S, Marx A, Janssen O and Kabelitz D (2001) Inhibition of protein synthesis by the T cell receptor-inducible human TDAG51 gene product. Cell. Signal. 13: 345-352
24. Ungefroren H, Voss M, Jansen M, Roeder C, Henne-Bruns D, Kremer B and Kalthoff H (1998) Human pancreatic adenocarcinomas express Fas and Fas Ligand yet are resistant to Fas-mediated apoptosis. Cancer Res. 58: 1741-1749
25. Favata MF, Horiuchi KY, Manos EL, Daulerio AJ, Stradley DA, Feeser WS, van Dyk DE, Pitts WJ, Earl RA, Hobbs F, Copeland RA, Magolda RL, Scherle PA and Trzaskos JM (1998) Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J. Biol. Chem. 273: 18623-18632
26. Dudley DT, Pang L, Decker SJ, Bridges AJ and Saltiel AR (1995) A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc. Natl. Acad. Sci. USA 92: 7686-7689
27. Davies SP, Reddy H, Caivano M and Cohen P (2000) Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem. J. 351: 95-105
28. Stempka L, Girod A, Müller HJ, Rincke G, Marks F, Gschwendt M and Bossemeyer D (1997) Phosphorylation of protein kinase C (PKC) at threonine 505 is not a prerequisite for enzymatic activity. Expression of rat PKC and an alanine 505 mutant in bacteria in a functional form. J. Biol. Chem. 272: 6805-6811
29. Uehara Y, Fukazawa H, Murakami Y and Mizuno S (1989) Irreversible inhibition of v-src tyrosine kinase activity by herbimycin A and its abrogation by sulfhydryl compounds. Biochem. Biophys. Res. Commun. 163: 803-809
30. Powis G, Bonjouklian MM, Berggren A, Gallegos R, Abraham C, Ashendel A, Zalkow W, Matter WF, Dodge J, Gridey G and Vlahos CJ (1994) Wortmannin, a potent and selective inhibitor of phosphatidylinositol-3-kinase. Cancer Res. 54: 2419-2423
31. Sawada S, Suzuki G, Kawase Y and Takaku F (1987) Novel immunosuppressive agent, FK506. In vitro effects on the cloned T cell activation. J. Immunol. 139: 1797-1803