The paired-related homeobox gene Prx1 is required for pulmonary vascular development
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Control of skeletal muscle-specific transcription: Involvement of paired homeodomain and MADS domain transcription factors
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Loss of function of the PRX1 and PRX2 homeobox genes alters architecture of the great elastic arteries and ductus arteriosus
Bergwerff M, Gittenberger-de Groot AC, Wisse L, DeRuiter MC, Wessels A, Martin JF, Olson EN, Kern MJ. Loss of function of the PRX1 and PRX2 homeobox genes alters architecture of the great elastic arteries and ductus arteriosus. Virchows Arch. 2000;436:12-19.
The paired-like homeo box gene MHox is required for early events of skeletogenesis in multiple lineages
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Patterns of paired-related homeobox genes PRX1 and PRX2 suggest involvement in matrix modulation in the developing chick vascular system
Bergwerff M, Gittenberger-de Groot AC, DeRuiter MC, van Iperen L, Meijlink F, Poelmann RE. Patterns of paired-related homeobox genes PRX1 and PRX2 suggest involvement in matrix modulation in the developing chick vascular system. Dev Dyn. 1998;3:59-70.
MHox: A mesodermally restricted homeodomain protein that binds an essential site in the muscle creatine kinase enhancer
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Prx1 controls vascular smooth muscle cell proliferation and tenascin-C expression and is upregulated with Prx2 in pulmonary vascular disease
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Persistent pulmonary hypertension of the newborn due to alveolar capillary dysplasia
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