Postprandial response of plasma ghrelin levels to various test meals in relation to food intake, plasma insulin, and glucose

Journal of Clinical Endocrinology and Metabolism

Volumn 89, Issue 6, 2004, Pages 3048-3054

  Erdmann, Johannes ^a   Töpsch, Robert ^a   Lippl, Florian ^a   Gussmann, Philipp ^a   Schusdziarra, Volker ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GHRELIN; GLUCOSE; INSULIN;

ADULT; CARBOHYDRATE INTAKE; CONFERENCE PAPER; CONTROLLED STUDY; FAT INTAKE; FEMALE; FOOD INTAKE; FRUIT; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN EXPERIMENT; HUNGER; INSULIN BLOOD LEVEL; MALE; NORMAL HUMAN; POSTPRANDIAL STATE; PRIORITY JOURNAL; PROTEIN INTAKE; SATIETY; VEGETABLE;

ADULT; BLOOD GLUCOSE; DIETARY CARBOHYDRATES; DIETARY PROTEINS; EATING; ENERGY METABOLISM; FEMALE; FRUIT; HUMANS; HUNGER; INSULIN; MALE; PEPTIDE HORMONES; POSTPRANDIAL PERIOD; SATIETY RESPONSE; VEGETABLES;

EID: 2942670568     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2003-031610     Document Type: Conference Paper

References (41)

1. Deutsch JA, Young WG, Kalogern TJ 1978 The stomach signals satiety. Science 201:165-167
2. Schick RR, Yaksh TL, Roddy DR, Go VLW 1989 Release of hypothalamic cholecystokinin in cats: effects of nutrient and volume loading. Am J Physiol 256:R248-R254
3. Kalra S, Dube MG, Pu S, Xu B, Horvath TL, Kalra PS 1999 Interacting appetite-regulating pathways in the hypothalamic regulation of body weight. Endocr Rev 20:68-100
4. Schwartz MW, Woods SC, Porte Jr D, Seeley RJ, Baskin DG 2000 Central nervous system control of food intake. Nature 404:661-671
5. Schick RR, Schusdziarra V 1994 Regulation of food intake. In: Ditschuneit H, Gries FA, Hauner H, Schusdziarra V, Wechsler JG, eds. Obesity in Europe 1993. London: John Libbey;, 335-348
6. Gonzalez MF, Deutsch JA 1978 Vagotomy abolishes cues of satiety produced by gastric distension. Science 165-167
7. Grossman MI, Cummings CM, Ivy CA 1947 The effect of insulin on food intake after vagotomy and sympathectomy. Am J Physiol 149:100-102
8. Davis JD, Gallagher RJ, Ladove RF 1967 Food intake controlled by a blood factor. Science 157:1247-1248
9. Davis JD, Gallagher RJ, Ladove RF, Turausky AJ 1969 Inhibition of food intake by a humoral factor. J Comp Physiol Psychol 67:407-414
10. Koopmans HS 1983 A stomach hormone that inhibits food intake. J Auton Nerv Syst 9:157-171
11. Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, Kangawa K 1999 Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402:656-660
12. Tschop M, Smiley DL, Herman ML 2000 Ghrelin induces adiposity in rodents. Nature 407:908-913
13. Cummings DE, Foster KE 2003 Ghrelin-leptin tango in body-weight regulation. Gastroenterology 124:1532-1535
14. Wren AM, Small CJ, Abbott CR, Dhillo WS, Seal LJ, Cohen MA, Batterham RL, Taheri S, Stanley SA, Ghatei MA, Bloom SR 2001 Ghrelin causes hyperphagia and obesity in rats. Diabetes 50:2540-2547
15. Wren AM, Small CJ, Ward HL, Murphy KG, Dakin CL, Taheri S, Kennedy AR, Roberts GH, Morgan DG, Ghatei MA, Bloom SR 2000 The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion. Endocrinology 141:4325-4328
16. Nakazato M, Murakami N, Date Y, Kojima M, Matsuo H, Kangawa K, Matsukura S 2001 A role for ghrelin in the central regulation of feeding. Nature 409:194-198
17. Asakawa A, Inui A, Kaga T, Yuzuriha H, Nagata T, Ueno N, Makino S, Fujimiya M, Niijima A, Fujino MA, Kasuga M 2001 Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin. Gastroenterology 120:337-345
18. Wren AM, Seal LJ, Cohen JA, Brynes AE, Frost GS, Murphy KG, Dhillo WS, Ghatei MA, Bloom SR 2001 Ghrelin enhances appetite and increases food intake in humans. J Clin Endocrinol Metab 86:5992-5995
19. Cummings DE, Purnell JQ, Frayo RS, Schmidova K, Wisse BE, Weigle DS 2001 A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans. Diabetes 50:1714-1719
20. Date Y, Murakami N, Toshinai K, Matsukura S, Niijima A, Matsuo H, Kangawa K, Nakazato M 2002 The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats. Gastroenterology 123:1120-1128
21. Shiiya T, Nakazato M, Mizuta M, Date Y, Mondal MS, Tanaka M, Nozoe S, Hosoda H, Kangawa K, Matsukura S 2002 Plasma ghrelin levels in lean and obese humans and the effect of glucose on ghrelin secretion. J Clin Endocrinol Metab 87:240-244
22. Erdmann J, Lippl F, Schusdziarra V 2003 Differential effect of protein and fat on ghrelin levels in man. Regul Pept 116:101-107
23. Blundell J, Rogers P, Hill A 1988 Evaluating the satiating power of foods: implications for acceptance and consumption. In: Solms J, ed. Chemical composition and sensory properties of food and their influence on nutrition. London: Academic Press; 205-219
24. Flint A, Raven A, Blundell J, Astrup A 2000 Reproducibility, validity and power of visual analogue scales in assessment of subjective appetite sensations in single meal test studies. Int J Obes Relat Metab Disord 24:38-48
25. Otto B, Cuntz U, Fruehauf E, Wawarta R, Folwaczny C, Riepl RL, Heiman ML, Lehnert P, Fichter M, Tschop M 2001 Weight gain decreases elevated plasma ghrelin concentrations of patients with anorexia nervosa. Eur J Endocrinol 145:669-673
26. Flanagan DE, Evans ML, Monsod TP, Rife F, Heptulla RA, Tamborlane WV, Sherwin RS 2003 The influence of insulin on circulating ghrelin. Am J Physiol Endocrinol Metab 284:E313-E316
27. Saad MF, Bernaba B, Hwu CM, Jinagouda S, Fahmi S, Kogosov E, Boyadjian R 2002 Insulin regulates plasma ghrelin concentration. J Clin Endocrinol Metab 87:3997-4000
28. Cummings DE, Weigle DS, Frayo RS, Breen PA, Ma MK, Dellinger EP, Purnell JQ 2002 Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery. N Engl J Med 346:1623-1630
29. Riis AL, Hansen TK, Moller N, Weeke J, Jorgensen JO 2003 Hyperthyroidism is associated with suppressed circulating ghrelin levels. J Clin Endocrinol Metab 88:853-857
30. Moller N, Nygren J, Hansen TK, Orskov H, Frystyk J, Nair KS 2003 Splanchnic release of ghrelin in humans. J Clin Endocrinol Metab 88:850-852
31. Asakawa A, Inui A, Kaga T, Katsuura G, Fujimiya M, Fujino MA, Kasuga M 2003 Antagonism of ghrelin receptor reduces food intake and body weight gain in mice. Gut 52:947-952
32. Schusdziarra V, Zyznar E, Rouillier D, Boden G, Brown JC, Arimura A, Unger RH 1980 Splanchnic somatostatin: a hormonal regulator of nutrient homeostasis. Science 207:530-532
33. Tschop M, Wawarta R, Riepl RL, Friedrich S, Bidlingmaier M, Landgraf R, Folwaczny C 2001 Post-prandial decrease of circulating human ghrelin levels. J Endocrinol Invest 24:RC19-RC21
34. Mohlig M, Spranger J, Otto B, Ristow M, Tschop M, Pfeiffer AF 2002 Euglycemic hyperinsulinemia, but not lipid infusion, decreases circulating ghrelin levels in humans. J Endocrinol Invest 25:RC36-RC38
35. Caixas A, Bashore C, Nash W, Pi-Sunyer F, Laferrere B 2002 Insulin, unlike food intake, does not suppress ghrelin in human subjects. J Clin Endocrinol Metab 87:1902
36. Schaller G, Schmidt A, Pleiner J, Woloszczuk W, Wolzt M, Luger A 2003 Plasma ghrelin concentrations are not regulated by glucose or insulin: a double-blind, placebo-controlled crossover clamp study. Diabetes 52:16-20
37. Lippl F, Kircher F, Erdmann J, Allescher HD, Schusdziarra V 2004 Effect GIP, GLP-1, insulin and gastrin on ghrelin release in the isolated rat stomach. Regul Pept 119:93-98
38. Masaoka T, Suzuki H, Hosoda H, Ota T, Minegishi Y, Nagata H, Kangawa K, Ishii H 2003 Enhanced plasma ghrelin levels in rats with streptozotocin-induced diabetes. FEBS Lett 541:64-68
39. Broglio F, Koetsveld PP, Benso A, Gottero C, Prodam F, Papotti M, Muccioli G, Gauna C, Hofland L, Deghenghi R, Arvat E, Van Der Lely AJ, Ghigo E 2002 Ghrelin secretion is inhibited by either somatostatin or cortistatin in humans. J Clin Endocrinol Metab 87:4829-4832
40. Reimer MK, Pacini G, Ahren B 2003 Dose-dependent inhibition by ghrelin of insulin secretion in the mouse. Endocrinology 144:916-921
41. Broglio F, Gottero C, Benso A, Prodam F, Destefanis S, Gauna C, Maccario M, Deghenghi, Van Der Lely AJ, Ghigo E 2003 Effects of ghrelin on the insulin and glycemic responses to glucose, arginine, or free fatty acids load in humans. J Clin Endocrinol Metab 88:4268-4272