The 1.59 Å Resolution Crystal Structure of TM0096, a Flavin Mononucleotide Binding Protein from Thermotoga maritima

Proteins: Structure, Function and Genetics

Volumn 55, Issue 3, 2004, Pages 772-774

  Park, Frances ^a   Gajiwala, Ketan ^a   Noland, Brian ^a   Wu, Lydia ^a   He, Dongmei ^a   Molinari, Janessa ^a   Loomis, Kim ^a   Pagarigan, Barbra ^a   Kearins, Peggy ^a   Christopher, Jon ^a   Peat, Tom ^a   Badger, John ^a   Hendle, Jorg ^a   Lin, Johann ^a   Buchanan, Sean ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; FLAVINE MONONUCLEOTIDE; OXIDOREDUCTASE; PROTEIN TM0096; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; CARRIER PROTEIN; FLAVINE MONONUCLEOTIDE REDUCTASE;

ARTICLE; CRYSTAL; CRYSTAL STRUCTURE; ENZYME ACTIVITY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN STRUCTURE; THERMOTOGA MARITIMA; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; X RAY CRYSTALLOGRAPHY;

BACTERIA (MICROORGANISMS); THERMOTOGA; THERMOTOGA MARITIMA;

BACTERIAL PROTEINS; CARRIER PROTEINS; CRYSTALLOGRAPHY, X-RAY; FLAVIN MONONUCLEOTIDE; FMN REDUCTASE; MODELS, MOLECULAR; THERMOTOGA MARITIMA;

EID: 2942659743     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/prot.20086     Document Type: Article

References (18)

1. Cullen PJ, Bowman WC, Hartnett DF, Reilly SC, Kranz RG. Translational activation by an NtrC enhancer-binding protein. J Mol Biol 1998;278:903-914.
2. Tourancheau AB, Morin L, Yang T, Perasso R. Messenger RNA in dormant cells of Sterkiella histriomuscorum (Oxytrichiade): indentification of putative regulatory gene transcripts. Protist 1999;150: 137-147.
3. Nelson KE, Clayton RA, Gill SR, Gwinn ML, Dodson RJ, Haft DH, Hickey EK, Peterson JD, Nelson WC, Ketchum KA and others. Evidence for lateral gene transfer between Archaea and bacteria from genome sequence of Thermotoga maritima. Nature 1999;399: 323-329.
4. CCP4. The CCP4 suite: programs for protein crystallography. Acta Crystallogr D Biol Crystallogr 1994;50:760-763.
5. Weeks CM, Miller R. The design and implementation of SnB version 2.0. J Appl Crystallogr (Part 1) 1999;32:120-124.
6. Perrakis A, Morris R, Lamzin VS. Automated protein model building combined with iterative structure refinement. Nat Struct Biol 1999;6:458-463.
7. McRee DE. XtalView Xfit - A versatile program for manipulating atomic coordinates and electron density. J Struct Biol 1999;125: 156-165.
8. Laskowski RA, Macarthur MW, Moss DS, Thornton JM. Procheck - a program to check the stereochemical quality of protein structures. J Appl Crystallogr 1993;26:283-291.
9. Vriend G. What if - a molecular modeling and drug design program. J Mol Graph 1990;8:52-56.
10. Vaguine AA, Richelle J, Wodak SJ. SFCHECK: a unified set of procedures for evaluating the quality of macromolecular structure-factor data and their agreement with the atomic model. Acta Crystallogr D Biol Crystallogr 1999;55:191-205.
11. Wilmanns M, Hyde CC, Davies DR, Kirschner K, Jansonius JN. Structural conservation in parallel beta/alpha-barrel enzymes that catalyze three sequential reactions in the pathway of tryptophan biosynthesis. Biochemistry 1991;30:9161-9169.
12. Gajiwala K; patent pending. Pub. no.: US-2003-0158671-A1.
13. Farber GK, Petsko GA. The evolution of alpha/beta barrel enzymes. Trends Biochem Sci 1990;15:228-234.
14. Holm L, Sander C. Protein structure comparison by alignment of distance matrices. J Mol Biol 1993;233:123-138.
15. Rowland P, Bjornberg O, Nielsen FS, Jensen KF, Larsen S. The crystal structure of Lactococcus lactis dihydroorotate dehydrogenase A complexed with the enzyme reaction product throws light on its enzymatic function. Protein Sci 1998;7:1269-1279.
16. Yang J, Dokurno P, Tonks NK, Barford D. Crystal structure of the M-fragment of alpha-catenin: implications for modulation of cell adhesion. Embo J 2001;20:3645-3656.
17. Christopher JA. SPOCK: The structural properties observation and calculation kit. College Station, TX: Texas A&M University; 1997.
18. DeLano WL. The PyMOL molecular graphics system. San Carlos, CA: DeLano Scientific; 2002.