Purification and pharmacological characterization of BmKK2 (α-KTx 14.2), a novel potassium channel-blocking peptide, from the venom of Asian scorpion Buthus martensi Karsch

Toxicon

Volumn 43, Issue 8, 2004, Pages 895-900

  Li, Ming Hua ^a   Zhang, Nai Xia ^b   Chen, Xue Qin ^a   Wu, Gong ^b   Wu, Houming ^b   Hu, Guo Yuan ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY   (China)

Author keywords

BmKK2; Buthus martensi Karsch; Delayed rectifier K+ current; Hippocampus; Neurotoxin; Scorpion

Indexed keywords

ALPHA POTASSIUM CHANNEL TOXIN; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; SCORPION VENOM; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BUTHUS MARTENSI; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEPOLARIZATION; DRUG PURIFICATION; HIPPOCAMPUS; NERVE CELL; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PEPTIDE ANALYSIS; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PURIFICATION; RAT; SCORPION; TOXIN ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GENE LIBRARY; MOLECULAR SEQUENCE DATA; NEURONS; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; RATS; SCORPION VENOMS; SCORPIONS; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, PROTEIN; TIME FACTORS;

BUTHUS; MESOBUTHUS MARTENSII; SCORPIONES;

EID: 2942644229     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2003.11.028     Document Type: Article

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