A K+ channel-blocking peptide from venom of Chinese scorpion Buthus martensii Karsch

Acta Pharmacologica Sinica

Volumn 19, Issue 4, 1998, Pages 317-321

  Wu, Gong ^a   Wei, Dong Sheng ^b   He, Fa Hu ^a   Hu, Guo Yuan ^b   Wu, Hou Ming ^a  

^a SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY   (China)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Neurotoxins; Patch clamp techniques; Potassium channels; Scorpion venom

Indexed keywords

POTASSIUM CHANNEL BLOCKING AGENT; SCORPION VENOM;

AMINO ACID COMPOSITION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; INHIBITION KINETICS; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PEPTIDE ANALYSIS; POTASSIUM TRANSPORT; PROTEIN PURIFICATION; RAT; SCORPION; SUBCUTANEOUS DRUG ADMINISTRATION; TOXICITY TESTING;

AMINO ACID SEQUENCE; ANIMALS; COCKROACHES; HIPPOCAMPUS; MALE; MICE; MOLECULAR SEQUENCE DATA; NEURONS; POTASSIUM CHANNEL BLOCKERS; RATS; RATS, SPRAGUE-DAWLEY; SCORPION VENOMS; SEQUENCE ALIGNMENT;

EID: 0042423694     PISSN: 02539756     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. Ji YH, Mansuelle P, Terakawa S, Kopeyan C, Yanaihara N, Hsu K, et al. Two neurotoxins (BMK I and BMK II) from the venom of the scorpion Buthus martensii Karsch: purification, amino acid sequences and assessment of specific activity. Toxicon 1996; 34: 987-1001.
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5. + channels with increased affinity. Biochemistry 1993; 32: 2763-70.
6. + channels. Int J Peptide Protein Res 1994; 43: 486-95.