A new insight into the Pfitzinger reaction. A facile synthesis of 6-sulfamoylquinoline-4-carboxylic acids

Tetrahedron Letters

Volumn 45, Issue 28, 2004, Pages 5473-5476

  Ivachtchenko, Alexandre V ^a   Khvat, Alexander V ^a   Kobak, Vladimir V ^a   Kysil, Volodymir M ^a   Williams, Caroline T ^a  

^a CHEMDIV INC   (United States)

Author keywords

5 Sulfamoylisatins; Acetaldehyde; Ethanol; Pfitzinger reaction; Quinoline 4 carboxylic acids

Indexed keywords

CARBOXYLIC ACID DERIVATIVE; QUINOLINE DERIVATIVE; SULFONAMIDE;

ARTICLE; HYDROLYSIS KINETICS; LABELING INDEX; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; SYNTHESIS;

EID: 2942642146     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2004.05.028     Document Type: Article

References (16)

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14. 4S: C, 57.47; H, 5.43; N, 8.38; S, 9.59. Found: C, 57.75; H, 5.84; N, 8.55; S, 10.05
15. 4S: 310.0944, found m/z 310.0944 [M+H]
16. 2O, OH), 6.95 (d, 1H, Ar), 7.61 (s, 1H, Ar), 7.66 (d, 1H, Ar), 10.69 (s, 1H, NH); m/z 285 [M+H]