2, 4-Diamino-6- hydroxy pyrimidine inhibits NSAIDs induced nitrosyl-complex EPR signals and ulcer in rat jejunum

BMC Gastroenterology

Volumn 2, Issue , 2002, Pages

  Somasundaram, S ^a   Simpson, Robert ^b   Rafi, Sue ^b   Shergill, J K ^c   Bjarnason, Ingvar ^b   Wrigglesworth, John ^c  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 DIAMINO 6 HYDROXYPYRIMIDINE; INDOMETACIN; NABUMETONE; NITRIC OXIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PYRIMIDINE DERIVATIVE; UBIQUINONE; UNCLASSIFIED DRUG; 2,4 DIAMINOHYPOXANTHINE; 2,4-DIAMINOHYPOXANTHINE; ALKANONE; HYPOXANTHINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DRUG BINDING; ELECTRON SPIN RESONANCE; ELECTRON TRANSPORT; ENTEROPATHY; GASTROINTESTINAL TOXICITY; IN VIVO STUDY; INTESTINE MUCOSA PERMEABILITY; JEJUNUM ULCER; MALE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; NITROSYLATION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PATHOGENESIS; RAT; RESPIRATORY CHAIN; ANIMAL; CELL MEMBRANE PERMEABILITY; CHEMICALLY INDUCED DISORDER; DRUG ANTAGONISM; DRUG EFFECT; JEJUNUM DISEASE; METABOLISM; SPRAGUE DAWLEY RAT; SUBMITOCHONDRIAL PARTICLE; ULCER;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BUTANONES; CELL MEMBRANE PERMEABILITY; ELECTRON SPIN RESONANCE SPECTROSCOPY; ELECTRON TRANSPORT; HYPOXANTHINES; JEJUNAL DISEASES; NITRIC OXIDE; RATS; RATS, SPRAGUE-DAWLEY; SUBMITOCHONDRIAL PARTICLES; ULCER;

EID: 2942624520     PISSN: 1471230X     EISSN: 1471230X     Source Type: Journal    
DOI: 10.1186/1471-230X-2-8     Document Type: Article

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