(+)-3-[2-(Benzo[b]thiophen-2-yl)-2-oxoethyl]-1-azabicyclo[2.2.2]-octane as potent agonists for the α7 nicotinic acetylcholine receptor

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 14, 2004, Pages 3781-3784

  Tatsumi, Ryo ^a   Seio, Kohji ^a,b   Fujio, Masakazu ^a   Katayama, Jiro ^a   Horikawa, Takashi ^a   Hashimoto, Kenji ^a,c   Tanaka, Hiroshi ^a  

^a MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

^b TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^c CHIBA UNIVERSITY   (Japan)

Author keywords

7 Nicotinic acetylcholine receptor

Indexed keywords

NICOTINIC AGENT; NICOTINIC RECEPTOR; OCTANE;

ANIMAL CELL; ARTICLE; DRUG POTENCY; DRUG SYNTHESIS; NONHUMAN; PHEOCHROMOCYTOMA CELL; RAT; STRUCTURE ACTIVITY RELATION;

ANIMALS; AZA COMPOUNDS; BICYCLO COMPOUNDS; BINDING SITES; DOSE-RESPONSE RELATIONSHIP, DRUG; MODELS, CHEMICAL; NICOTINIC AGONISTS; OCTANES; PC12 CELLS; RATS; RECEPTORS, NICOTINIC; THIOPHENES;

EID: 2942620549     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.04.091     Document Type: Article

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