Variant MYST4-CBP gene fusion in a t(10;16) acute myeloid leukaemia

British Journal of Haematology

Volumn 125, Issue 5, 2004, Pages 601-604

  Murati, Anne ^a   Adélaïde, José ^a   Mozziconacci, Marie Joëlle ^a   Popovici, Cornel ^a   Carbuccia, Nadine ^a   Letessier, Anne ^a   Birg, Françoise ^a   Birnbaum, Daniel ^a   Chaffanet, Max ^a  

^a INSTITUT PAOLI CALMETTES   (France)

Author keywords

Acute myeloid leukaemia; MYST4 CBP fusion transcript; t(10; 16)

Indexed keywords

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; ARTICLE; CASE REPORT; CHIMERA; CHROMOSOME TRANSLOCATION 10; CLINICAL FEATURE; EXON; FEMALE; GENE FUSION; GENE REARRANGEMENT; GENETIC VARIABILITY; HUMAN; PRIORITY JOURNAL;

ACUTE DISEASE; ARTIFICIAL GENE FUSION; CHIMERA; CHROMOSOMES, HUMAN, PAIR 10; CHROMOSOMES, HUMAN, PAIR 16; FEMALE; GENE REARRANGEMENT; HUMANS; LEUKEMIA, MYELOID; TRANSLOCATION, GENETIC;

EID: 2942616378     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2004.04960.x     Document Type: Article

References (12)

1. Hayashi, Y. (2000) The molecular genetics of recurring chromosome abnormalities in acute myeloid leukaemia. Seminars in Hematology, 37, 368-380.
2. Ida, K., Kitabayashi, I., Taki, T., Taniwaki, M., Noro, K., Yamamoto, M., Ohki, M. & Hayashi, Y. (1997) Adenoviral E1A-associated protein p300 is involved in acute myeloid leukemia with t(11;22)(q23;q13). Blood, 90, 4699-4704.
3. Imamura, T., Kakazu, N., Hibi, S., Morimoto, A., Fukushima, Y., Ijuin, I., Hada, S., Kitabayashi, I., Abe, T. & Imashuku, S. (2003) Rearrangement of the MOZ gene in pediatric therapy-related myelodysplastic syndrome with a novel chromosomal translocation t(2;8)(p23;p11). Genes Chromosomes and Cancer, 36, 413-419.
4. Kojima, K., Kaneda, K., Yoshida, C., Dansako, H., Fujii, N., Yano, T., Shinagawa, K., Yasukawa, M., Fujita, S. & Tanimoto, M. (2003) A novel fusion variant of the MORF and CBP genes detected in therapy-related myelodysplastic syndrome with t(10;16)(q22;p13). British Journal of Haematology, 120, 271-273.
5. Mathew, S., Head, D., Rubnitz, J.E. & Raimondi, S.C. (2000) Concurrent translocations of MLL and CBFA2 (AML1) genes with new partner breakpoints in a child with secondary myelodysplastic syndrome after treatment of acute lymphoblastic leukemia. Genes Chromosomes and Cancer, 28, 227-232.
6. Murati, A., Adélaïde, J., Popovici, C., Mozziconacci, M.-J., Arnoulet, C., Lafage-Pochitaloff, M., Sainty, D., Birnbaum, D. & Chaffanet, M. (2003) A further case of acute myelomonocytic leukemia with inv(8) chromosomal rearrangement and MOZ-NCOA2 gene fusion. International Journal of Molecular Medicine, 12, 423-428.
7. Panagopoulos, I., Fioretos, T., Isaksson, M., Samuelsson, U., Billstrom, R., Strombeck, B., Mitelman, F. & Johansson, B. (2001) Fusion of the MORF and CBP genes in acute myeloid leukemia with the t(10;16)(q22;p13). Human Molecular Genetics, 10, 395-404.
8. Pébusque, M.J., Lafage, M., Lopez, M. & Mannoni, P. (1988) Preferential response of acute myeloid leukemias with translocation involving chromosome 17 to human recombinant granulocyte colony-stimulating factor. Blood, 72, 257-265.
9. Pébusque, M.J., Chaffanet, M., Popovici, C. & Birnbaum, D. (2000) FGFR1 and MOZ, two key genes involved in malignant hemopathies linked to rearrangements within the chromosomal region 8p11-12. Bulletin du Cancer, 87, 887-894.
10. Pelletier, N., Champagne, N., Stifani, S. & Yang, X.J. (2002) MOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2. Oncogene, 21, 2729-2740.
11. Sobulo, O.M., Borrow, J., Tomek, R., Reshmi, S., Harden, A., Schlegelberger, B., Housman, D., Doggett, N.A., Rowley, J.D. & Zeleznik-Le, N.J. (1997) MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3). Proceedings of the National Academy of Sciences of the United States of America, 94, 8732-8737.
12. Vizmanos, J.L., Larrayoz, M.J., Lahortiga, I., Floristan, F., Alvarez, C., Odero, M.D., Novo, F.J. & Calasanz, M.J. (2003) t(10;16)(q22;p13) and MORF-CREBBP fusion is a recurrent event in acute myeloid leukemia. Genes Chromosomes and Cancer, 36, 402-405.