Design of 1-substituted 2-arylmethyl-4,5-methylenedioxybenzene derivatives as antiseizure agents

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 13, 2004, Pages 3703-3709

  Micale, Nicola ^a   De Sarro, Giovambattista ^b   Ferreri, Guido ^b   Zappalá, Maria ^a   Grasso, Silvana ^a   Puia, Giulia ^c   De Micheli, Carlo ^d  

^a UNIVERSITY OF MESSINA   (Italy)

^b UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^c UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^d UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

1 (4 AMINOPHENYL) 3,4 DIHYDRO 4 METHYL 3 METHYLCARBAMOYL 7,8 METHYLENEDIOXY 5H 2,3 BENZODIAZEPINE; 1,3 BENZODIOXOLE DERIVATIVE; 2 [2 [4 AMINOPHENYL (4 METHYLSEMICARBAZONO)METHYL] 4,5 METHYLENEDIOXYPHENYL] N METHYLACETAMIDE; 2 [4 ACETYLHYDRAZONO (4 AMINOPHENYL)METHYL] 4,5 METHYLENEDIOXYTOLUENE; 2 [4 AMINOPHENYL (4 METHYLSEMICARBAZONO)METHYL] 4,5 METHYLENEDIOXYPHENYLACETIC ACID METHYL ESTER; 2 [4 AMINOPHENYL (4 METHYLSEMICARBAZONO)METHYL] 4,5 METHYLENEDIOXYTOLUENE; 2 [4 AMINOPHENYL (4 METHYLTHIOSEMICARBAZONO)METHYL] 4,5 METHYLENEDIOXYPHENYLACETIC ACID METHYL ESTER; 2 [4 AMINOPHENYL (4 METHYLTHIOSEMICARBAZONO)METHYL] 4,5 METHYLENEDIOXYTOLUENE; 2 [4 AMINOPHENYL (4 SEMICARBAZONO)METHYL] 4,5 METHYLENEDIOXYTOLUENE; 2 [4 BROMOPHENYL (4 METHYLSEMICARBAZONO)METHYL] 4,5 METHYLENEDIOXYPHENYLACETIC ACID METHYL ESTER; 2 [4 BROMOPHENYL (4 METHYLTHIOSEMICARBAZONO)METHYL] 4,5 METHYLENEDIOXYPHENYLACETIC ACID METHYL ESTER; 2 [4 CHLOROPHENYL (4 METHYLSEMICARBAZONO)METHYL] 4,5 METHYLENEDIOXYPHENYLACETIC ACID METHYL ESTER; 2 [4 CHLOROPHENYL (4 METHYLTHIOSEMICARBAZONO)METHYL] 4,5 METHYLENEDIOXYPHENYLACETIC ACID METHYL ESTER; 2 [4 FLUOROPHENYL (4 METHYLSEMICARBAZONO)METHYL] 4,5 METHYLENEDIOXYPHENYLACETIC ACID METHYL ESTER; 2 [4 FLUOROPHENYL (4 METHYLTHIOSEMICARBAZONO)METHYL] 4,5 METHYLENEDIOXYPHENYLACETIC ACID METHYL ESTER; AMPA RECEPTOR ANTAGONIST; ANTICONVULSIVE AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; MOUSE; NONHUMAN; SEIZURE;

ANIMALS; ANTICONVULSANTS; BENZENE; CELLS, CULTURED; DIOXOLES; DRUG DESIGN; FEMALE; MALE; MICE; MICE, INBRED DBA; MOLECULAR STRUCTURE; NEURONS; SEIZURES;

EID: 2942608086     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.04.015     Document Type: Article

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