Production of nonproteinaceous amino acids using recombinant Escherichia coli cells expressing cysteine synthase and related enzymes with or without the secretion of O-acetyl-L-serine

Journal of Bioscience and Bioengineering

Volumn 97, Issue 5, 2004, Pages 322-328

  Zhao, Chunhui ^a   Ohno, Katsuhiro ^a   Sogoh, Kohji ^a   Imamura, Koreyoshi ^a   Sakiyama, Takaharu ^a   Nakanishi, Kazuhiro ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

Cysteine synthase; Escherichia coli; Nonproteinaceous amino acid; O acetyl L serine; (pyrazol 1 yl) L alanine

Indexed keywords

AMINO ACIDS; BIOSYNTHESIS; CELLS; ENZYMES; GLUCOSE; SUBSTRATES;

CELL EXPRESSIONS; RECOMBINANT CELLS;

ESCHERICHIA COLI;

3 (1 PYRAZOLYL)ALANINE; ACETATE KINASE; AMINO ACID DERIVATIVE; BACTERIAL ENZYME; CYSTEINE SYNTHASE; GLUCOSE; O ACETYLSERINE; PHOSPHATE ACETYLTRANSFERASE; PYRAZOLE; SERINE; SERINE ACETYLTRANSFERASE; SERINE DERIVATIVE; UNCLASSIFIED DRUG;

AMINO ACID SYNTHESIS; ARTICLE; BACTERIAL CELL; CONTROLLED STUDY; ENZYME SUBSTRATE; ESCHERICHIA COLI; MODEL; NONHUMAN; PROTEIN EXPRESSION; TECHNIQUE; WILD TYPE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA;

EID: 2942594379     PISSN: 13891723     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1389-1723(04)70213-3     Document Type: Review

References (25)

1. Kredich, N. M.: Biosynthesis of cysteine, p.514-527. In Neidhardt, F. C. (ed.), Escherichia coli and Salmonella typhimurium: cellular and molecular biology, 2nd ed., vol. 1. American Society of Microbiology, Washington, D.C. (1996).
2. Hell, R.: Molecular physiology of plant sulfur metabolism. Planta, 202, 138-148 (1997).
3. Giovanelli, J., Mudd, S. H., and Datko, A. H.: Sulfur amino acids in plants, p. 453-505. In Miflin, B. J. (ed.), The biochemistry of plants, vol. 5. Academic Press, New York (1980).
4. Schmidt, A. and Jäger, K.: Open questions about sulfur metabolism in plants. Annu. Rev. Plant Physiol. Plant Mol. Biol., 43, 325-349 (1992).
5. Flint, D. H., Tuminello, J. F., and Miller, T. J.: Studies on the synthesis of the Fe-S cluster of dihydroxy-acid dehydratase in Escherichia coli crude extract. J. Biol. Chem., 271, 16053-16067 (1996).
6. Ikegami, F. and Murakoshi, I.: Enzymic synthesis of non-protein β-substituted alanines and some higher homologues in plants. Phytochemistry, 35, 1089-1104 (1994).
7. Ikegami, F., Kusama-Eguchi, K., Sugiyama, E., Watanabe, K., Lambein, F., and Murakoshi, I.: Interaction of some plant heterocyclic beta-substitued alanines with rat brain N-methyl-D-aspartate (NMDA) receptors. Biol. Pharm. Bull., 18, 360-362 (1994).
8. Saito, K.: Molecular biology and engineering of biosynthesis of cysteine and biogenetically related non-protein amino acids in plants, p. 227-243. In Ogura, K. and Sankawa, U. (ed.), Dynamic aspects of natural products chemistry. Kodansha, Tokyo (1997).
9. Maier, T. H. P.: Semisynthetic production of unnatural L-α-amino acids by metabolic engineering of the cysteine-biosynthetic pathway. Nat. Biotechnol., 21, 422-427 (2003).
10. 2. Substitution of histidine by 1,2,4-triazole-3-alanine yields an enzyme with high activity at acidic pH. Protein Eng., 9, 345-352 (1996).
11. Imamura, N., Murata, M., Yao, T., Oiwa, R., Tanaka, H., and Omura, S.: Occurrence of 1,2,4-triazole ring in actinomycetes. J. Antibiot., 38, 1110-1111 (1985).
12. Mino, K., Yamanoue, T., Ohno, K., Sakiyama, T., Eisaki, N., Matsuyama, A., and Nakanishi, K.: Production of β-(pyrazol-1-yl)-L-alanine from L-serine and pyrazole using recombinant Escherichia coli cells expressing serine acetyltransferase and O-acetylserine sulfhydrylase-A. Biotechnol. Lett., 23, 2051-2055 (2001).
13. Sambrook, J. and Russell, D. W.: Molecular cloning: a laboratory manual, 3rd ed. Cold Spring Harbor Laboratory Press, New York (2001).
14. Mino, K., Yamanoue, T., Sakiyama, T., Eisaki, N., Matsuyama, A., and Nakanishi, K.: Purification and characterization of serine acetyltransferase from Escherichia coli partially truncated at the C-terminal region. Biosci. Biotechnol. Biochem., 63, 168-179 (1999).
15. Gaitonde, M. K.: A spectrophotometric method for the direct determination of cysteine in the presence of other naturally occurring amino acids. Biochem. J., 104, 627-633 (1967).
16. Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J.: Protein measurement with the Folin phenol reagent. J. Biol. Chem., 193, 265-275 (1951).
17. Saito, K., Kimura, N., Ikegami, F., and Noji, M.: Production of plant non-protein amino acids by recombinant enzymes of sequential biosynthetic reactions in bacteria. Biol. Pharm. Bull., 20, 47-53 (1997).
18. Nakajima, H., Suzuki, K., and Imahori, K.: Purification and properties of acetate kinase from Bacillus stearothermophilus. J. Biochem., 84, 193-203 (1978).
19. Kredich, N. M. and Tomkins, G. M.: The enzymic synthesis of L-cysteine in Escherichia coli and Salmonella typhimurium. J. Biol. Chem., 241, 4955-4965 (1966).
20. Mino, K., Yamanoue, T., Sakiyama, T., Eisaki, N., Matsuyama, A., and Nakanishi, K.: Effects of bienzyme complex formation of cysteine synthetase from Escherichia coli on some properties and kinetics. Biosci. Biotechnol. Biochem., 64, 1628-1640 (2000).
21. Nakamori, S., Kobayashi, S., Kobayashi, C., and Takagi, H.: Overproduction of L-cysteine and L-cystine by Escherichia coli strains with a genetically altered serine acetyltransferase. Appl. Environ. Microbiol., 64, 1607-1611 (1998).
22. Takagi, H., Kobayashi, C., Kobayashi, S., and Nakamori, S.: PCR random mutagenesis into Escherichia coli serine acetyltransferase: isolation of the mutant enzymes that cause overproduction of L-cysteine and L-cystine due to the desensitization to feedback inhibition. FEBS Lett., 452, 323-327 (1999).
23. Takagi, H., Awano, N., Kobayashi, S., Noji, M., Saito, K., and Nakamori, S.: Overproduction of L-cysteine and L-cystine by expression of genes for feedback inhibition-insensitive serine acetyltransferase from Arabidopsis thaliana in Escherichia coli. FEMS Microbiol. Lett., 179, 453-459 (1999).
24. Sorensen, M. A. and Pedersen, S.: Cysteine, even in low concentrations, induces transient amino acid starvation in Escherichia coli. J. Bacteriol., 173, 5244-5246 (1991).
25. Delaney, J. M., Ang, D., and Georgopoulos, C.: Isolation and characterization of the Escherichia coli htrD gene, whose product is required for growth at high temperatures. J. Bacteriol., 174, 1240-1247 (1992).