메뉴 건너뛰기




Volumn 38, Issue 11, 2004, Pages 1613-1622

Effectiveness of antiretroviral therapy after protease inhibitor failure: An analytic overview

Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR; AMPRENAVIR; ANTIRETROVIRUS AGENT; DELAVIRDINE; DIPIVOXIL; EFAVIRENZ; LOPINAVIR; NELFINAVIR; NEVIRAPINE; PROTEINASE INHIBITOR; SAQUINAVIR; STAVUDINE; UNCLASSIFIED DRUG; VIRUS RNA;

EID: 2942592207     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/420930     Document Type: Review
Times cited : (9)

References (85)
  • 1
    • 0037182766 scopus 로고    scopus 로고
    • Lopinavir-ritonavir versus nelfinavir for the initial treatment of HIV infection
    • Walmsley S, Bernstein B, King M, et al. Lopinavir-ritonavir versus nelfinavir for the initial treatment of HIV infection. N Engl J Med 2002; 346:2039-46.
    • (2002) N Engl J Med , vol.346 , pp. 2039-2046
    • Walmsley, S.1    Bernstein, B.2    King, M.3
  • 2
    • 0345012053 scopus 로고    scopus 로고
    • Comparison of sequential three-drug regimens as initial therapy for HIV-1 infection
    • Robbins GK, De Gruttola V, Shafer RW, et al. Comparison of sequential three-drug regimens as initial therapy for HIV-1 infection. N Engl J Med 2003; 349:2293-303.
    • (2003) N Engl J Med , vol.349 , pp. 2293-2303
    • Robbins, G.K.1    De Gruttola, V.2    Shafer, R.W.3
  • 3
    • 0033576816 scopus 로고    scopus 로고
    • Efavirenz plus zidovudine and lamivudine, efavirenz plus indinavir, and indinavir plus zidovudine and lamivudine in the treatment of HIV-1 infection in adults
    • Study 006 Team
    • Staszewski S, Morales-Ramirez J, Tashima KT, et al. Efavirenz plus zidovudine and lamivudine, efavirenz plus indinavir, and indinavir plus zidovudine and lamivudine in the treatment of HIV-1 infection in adults. Study 006 Team. N Engl J Med 1999; 341:1865-73.
    • (1999) N Engl J Med , vol.341 , pp. 1865-1873
    • Staszewski, S.1    Morales-Ramirez, J.2    Tashima, K.T.3
  • 4
    • 0035958773 scopus 로고    scopus 로고
    • Overview of the effectiveness of triple combination therapy in antiretroviral-naive HIV-1 infected adults
    • Bartlett JA, DeMasi R, Quinn J, Moxham C, Rousseau F. Overview of the effectiveness of triple combination therapy in antiretroviral-naive HIV-1 infected adults. AIDS 2001; 15:1369-77.
    • (2001) AIDS , vol.15 , pp. 1369-1377
    • Bartlett, J.A.1    DeMasi, R.2    Quinn, J.3    Moxham, C.4    Rousseau, F.5
  • 5
    • 0033614552 scopus 로고    scopus 로고
    • Better salvage therapy for HIV-1 infection still needed
    • Montaner J, Mellors J. Better salvage therapy for HIV-1 infection still needed. Lancet 1999; 353:1857.
    • (1999) Lancet , vol.353 , pp. 1857
    • Montaner, J.1    Mellors, J.2
  • 6
    • 0035808534 scopus 로고    scopus 로고
    • Multiple drug rescue therapy for HIV-infected individuals with prior virologic failure to multiple regimens
    • Montaner JS, Harrigan PR, Jahnke N, et al. Multiple drug rescue therapy for HIV-infected individuals with prior virologic failure to multiple regimens. AIDS 2001; 15:61-9.
    • (2001) AIDS , vol.15 , pp. 61-69
    • Montaner, J.S.1    Harrigan, P.R.2    Jahnke, N.3
  • 8
    • 0023181949 scopus 로고
    • Inter-study differences: How should they influence the interpretation and analysis of results?
    • Bailey KR. Inter-study differences: how should they influence the interpretation and analysis of results? Stat Med 1987; 6:351-60.
    • (1987) Stat Med , vol.6 , pp. 351-360
    • Bailey, K.R.1
  • 9
    • 0026075512 scopus 로고
    • Reliability of retrospective assessments of sexual HIV risk behavior: A comparison of biweekly, three-month, and twelve-month self-reports
    • Kauth MR, St Lawrence JS, Kelly JA. Reliability of retrospective assessments of sexual HIV risk behavior: a comparison of biweekly, three-month, and twelve-month self-reports. AIDS Educ Prev 1991; 3:207-14.
    • (1991) AIDS Educ Prev , vol.3 , pp. 207-214
    • Kauth, M.R.1    St Lawrence, J.S.2    Kelly, J.A.3
  • 10
    • 0027253135 scopus 로고
    • A meta-analysis of condom effectiveness in reducing sexually transmitted HIV
    • Weller SC. A meta-analysis of condom effectiveness in reducing sexually transmitted HIV. Soc Sci Med 1993; 36:1635-44.
    • (1993) Soc Sci Med , vol.36 , pp. 1635-1644
    • Weller, S.C.1
  • 12
    • 0029736814 scopus 로고    scopus 로고
    • A meta-analysis of estimates of the AIDS incubation distribution
    • Cooley PC, Myers LE, Hamill DN. A meta-analysis of estimates of the AIDS incubation distribution. Eur J Epidemiol 1996; 12:229-35.
    • (1996) Eur J Epidemiol , vol.12 , pp. 229-235
    • Cooley, P.C.1    Myers, L.E.2    Hamill, D.N.3
  • 13
    • 0030777744 scopus 로고    scopus 로고
    • Meta-analysis for the evaluation of potential surrogate markers
    • Daniels MJ, Hughes MD. Meta-analysis for the evaluation of potential surrogate markers. Stat Med 1997; 16:1965-82.
    • (1997) Stat Med , vol.16 , pp. 1965-1982
    • Daniels, M.J.1    Hughes, M.D.2
  • 14
    • 0037196929 scopus 로고    scopus 로고
    • Systematic review and meta-analysis of evidence for increasing numbers of drugs in antiretroviral combination therapy
    • Jordan R, Gold L, Cummins C, Hyde C. Systematic review and meta-analysis of evidence for increasing numbers of drugs in antiretroviral combination therapy. BMJ 2002; 324:757.
    • (2002) BMJ , vol.324 , pp. 757
    • Jordan, R.1    Gold, L.2    Cummins, C.3    Hyde, C.4
  • 15
    • 0032990266 scopus 로고    scopus 로고
    • Novel four-drug salvage treatment regimens after failure of a human immunodeficiency virus type 1 protease inhibitor-containing regimen: Antiviral activity and correlation of baseline phenotypic drug susceptibility with virologic outcome
    • Deeks SG, Hellmann NS, Grant RM, et al. Novel four-drug salvage treatment regimens after failure of a human immunodeficiency virus type 1 protease inhibitor-containing regimen: antiviral activity and correlation of baseline phenotypic drug susceptibility with virologic outcome. J Infect Dis 1999; 179:1375-81.
    • (1999) J Infect Dis , vol.179 , pp. 1375-1381
    • Deeks, S.G.1    Hellmann, N.S.2    Grant, R.M.3
  • 16
    • 0037055027 scopus 로고    scopus 로고
    • Dual vs single protease inhibitor therapy following antiretroviral treatment failure: A randomized trial
    • Hammer SM, Vaida F, Bennett KK, et al. Dual vs single protease inhibitor therapy following antiretroviral treatment failure: a randomized trial. JAMA 2002; 288:169-80.
    • (2002) JAMA , vol.288 , pp. 169-180
    • Hammer, S.M.1    Vaida, F.2    Bennett, K.K.3
  • 17
    • 12944314948 scopus 로고    scopus 로고
    • Efavirenz- and adefovir dipivoxil-based salvage therapy in highly treatment-experienced patients: Clinical and genotypic predictors of virologic response
    • Shulman NS, Zolopa AR, Passaro DJ, et al. Efavirenz- and adefovir dipivoxil-based salvage therapy in highly treatment-experienced patients: clinical and genotypic predictors of virologic response. J Acquir Immune Defic Syndr 2000; 23:221-6.
    • (2000) J Acquir Immune Defic Syndr , vol.23 , pp. 221-226
    • Shulman, N.S.1    Zolopa, A.R.2    Passaro, D.J.3
  • 19
    • 0024546358 scopus 로고
    • A comparison of statistical methods for combining event rates from clinical trials
    • Berlin JA, Laird NM, Sacks HS, Chalmers TC. A comparison of statistical methods for combining event rates from clinical trials. Stat Med 1989; 8:141-51.
    • (1989) Stat Med , vol.8 , pp. 141-151
    • Berlin, J.A.1    Laird, N.M.2    Sacks, H.S.3    Chalmers, T.C.4
  • 21
    • 0036499067 scopus 로고    scopus 로고
    • Safety and antiviral activity at 48 weeks of lopinavir/ritonavir plus nevirapine and 2 nucleoside reverse-transcriptase inhibitors in human immunodeficiency virus type 1-infected protease inhibitor-experienced patients
    • Benson CA, Deeks SG, Brun SC, et al. Safety and antiviral activity at 48 weeks of lopinavir/ritonavir plus nevirapine and 2 nucleoside reverse-transcriptase inhibitors in human immunodeficiency virus type 1-infected protease inhibitor-experienced patients. J Infect Dis 2002; 185:599-607.
    • (2002) J Infect Dis , vol.185 , pp. 599-607
    • Benson, C.A.1    Deeks, S.G.2    Brun, S.C.3
  • 22
    • 0033033234 scopus 로고    scopus 로고
    • HIV RNA and CD4 cell count response to protease inhibitor therapy in an urban AIDS clinic: Response to both initial and salvage therapy
    • Deeks SG, Hecht FM, Swanson M, et al. HIV RNA and CD4 cell count response to protease inhibitor therapy in an urban AIDS clinic: response to both initial and salvage therapy. AIDS 1999; 13:F35-43.
    • (1999) AIDS , vol.13
    • Deeks, S.G.1    Hecht, F.M.2    Swanson, M.3
  • 23
    • 0036148608 scopus 로고    scopus 로고
    • Amprenavir inhibitory quotient and virological response in human immunodeficiency virus-infected patients on an amprenavir-containing salvage regimen without or with ritonavir
    • Duval X, Lamotte C, Race E, et al. Amprenavir inhibitory quotient and virological response in human immunodeficiency virus-infected patients on an amprenavir-containing salvage regimen without or with ritonavir. Antimicrob Agents Chemother 2002; 46:570-4.
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 570-574
    • Duval, X.1    Lamotte, C.2    Race, E.3
  • 24
    • 0033794231 scopus 로고    scopus 로고
    • Randomized study of saquinavir with ritonavir or nelfinavir together with delavirdine, adefovir, or both in human immunodeficiency virus-infected adults with virologic failure on indinavir: AIDS Clinical Trials Group study 359
    • Gulick RM, Hu XJ, Fiscus SA, et al. Randomized study of saquinavir with ritonavir or nelfinavir together with delavirdine, adefovir, or both in human immunodeficiency virus-infected adults with virologic failure on indinavir: AIDS Clinical Trials Group study 359. J Infect Dis 2000; 182:1375-84.
    • (2000) J Infect Dis , vol.182 , pp. 1375-1384
    • Gulick, R.M.1    Hu, X.J.2    Fiscus, S.A.3
  • 25
    • 0037114877 scopus 로고    scopus 로고
    • Open-label study of a twice-daily indinavir 800-mg/ritonavir 200-mg regimen in HIV-infected adults failing a protease inhibitor regimen
    • Katner HP, Paar DP, Nadler JP, et al. Open-label study of a twice-daily indinavir 800-mg/ritonavir 200-mg regimen in HIV-infected adults failing a protease inhibitor regimen. J Acquir Immune Defic Syndr 2002; 31:483-7.
    • (2002) J Acquir Immune Defic Syndr , vol.31 , pp. 483-487
    • Katner, H.P.1    Paar, D.P.2    Nadler, J.P.3
  • 26
    • 0036768328 scopus 로고    scopus 로고
    • Analysis of the virological response with respect to baseline viral phenotype and genotype in protease inhibitor-experienced HIV-1-infected patients receiving lopinavir/ritonavir therapy
    • Kempf DJ, Isaacson JD, King MS, et al. Analysis of the virological response with respect to baseline viral phenotype and genotype in protease inhibitor-experienced HIV-1-infected patients receiving lopinavir/ritonavir therapy. Antivir Ther 2002; 7:165-74.
    • (2002) Antivir Ther , vol.7 , pp. 165-174
    • Kempf, D.J.1    Isaacson, J.D.2    King, M.S.3
  • 27
    • 0011089839 scopus 로고    scopus 로고
    • Salvage therapy with abacavir plus a non-nucleoside reverse transcriptase inhibitor and a protease inhibitor in heavily pre-treated HIV-1 infected patients. Swiss HIV Cohort Study
    • Khanna N, Klimkait T, Schiffer V, et al. Salvage therapy with abacavir plus a non-nucleoside reverse transcriptase inhibitor and a protease inhibitor in heavily pre-treated HIV-1 infected patients. Swiss HIV Cohort Study. AIDS 2000; 14:791-9.
    • (2000) AIDS , vol.14 , pp. 791-799
    • Khanna, N.1    Klimkait, T.2    Schiffer, V.3
  • 28
    • 0035986051 scopus 로고    scopus 로고
    • The HYDILE trial: Efficacy and tolerance of a quadruple combination of reverse transcriptase inhibitors versus the same regimen plus hydroxyurea or hydroxyurea and interleukin-2 in HIV-infected patients failing protease inhibitor-based combinations
    • Lafeuillade A, Hittinger G, Chadapaud S, Maillefet S, Rieu A, Poggi C. The HYDILE trial: efficacy and tolerance of a quadruple combination of reverse transcriptase inhibitors versus the same regimen plus hydroxyurea or hydroxyurea and interleukin-2 in HIV-infected patients failing protease inhibitor-based combinations. HIV Clin Trials 2002; 3:263-71.
    • (2002) HIV Clin Trials , vol.3 , pp. 263-271
    • Lafeuillade, A.1    Hittinger, G.2    Chadapaud, S.3    Maillefet, S.4    Rieu, A.5    Poggi, C.6
  • 29
    • 0032839921 scopus 로고    scopus 로고
    • Efficacy of a five-drug combination including ritonavir, saquinavir and efavirenz in patients who failed on a conventional triple-drug regimen: Phenotypic resistance to protease inhibitors predicts outcome of therapy
    • Piketty C, Race E, Castiel P, et al. Efficacy of a five-drug combination including ritonavir, saquinavir and efavirenz in patients who failed on a conventional triple-drug regimen: phenotypic resistance to protease inhibitors predicts outcome of therapy. AIDS 1999; 13:F71-7.
    • (1999) AIDS , vol.13
    • Piketty, C.1    Race, E.2    Castiel, P.3
  • 30
    • 0035576120 scopus 로고    scopus 로고
    • Baseline CD4(+) cell count, not viral load, correlates with virologic suppression induced by potent antiretroviral therapy
    • Skowron G, Street JC, Obee EM. Baseline CD4(+) cell count, not viral load, correlates with virologic suppression induced by potent antiretroviral therapy. J Acquir Immune Defic Syndr 2001; 28:313-9.
    • (2001) J Acquir Immune Defic Syndr , vol.28 , pp. 313-319
    • Skowron, G.1    Street, J.C.2    Obee, E.M.3
  • 31
    • 0038576281 scopus 로고    scopus 로고
    • Enfuvirtide, an HIV-1 fusion inhibitor, for drug-resistant HIV infection in North and South America
    • Lalezari JP, Henry K, O'Hearn M, et al. Enfuvirtide, an HIV-1 fusion inhibitor, for drug-resistant HIV infection in North and South America. N Engl J Med 2003; 348:2175-85.
    • (2003) N Engl J Med , vol.348 , pp. 2175-2185
    • Lalezari, J.P.1    Henry, K.2    O'Hearn, M.3
  • 32
    • 0037228452 scopus 로고    scopus 로고
    • Sequencing to NRTI plus NNRTI-only combinations after virological failure of protease inhibitor-based combination HIV-1 therapy
    • Asboe D, Mandalia S, Gazzard BG. Sequencing to NRTI plus NNRTI-only combinations after virological failure of protease inhibitor-based combination HIV-1 therapy. HIV Clin Trials 2003; 4:1-10.
    • (2003) HIV Clin Trials , vol.4 , pp. 1-10
    • Asboe, D.1    Mandalia, S.2    Gazzard, B.G.3
  • 33
    • 0034087765 scopus 로고    scopus 로고
    • Higher short-term virologic efficacy of three-class versus two-class highly active antiretroviral salvage therapy in HIV-infected patients
    • Baldanti F, Paolucci S, Maserati R, et al. Higher short-term virologic efficacy of three-class versus two-class highly active antiretroviral salvage therapy in HIV-infected patients. Eur J Clin Microbiol Infect Dis 2000; 19:380-4.
    • (2000) Eur J Clin Microbiol Infect Dis , vol.19 , pp. 380-384
    • Baldanti, F.1    Paolucci, S.2    Maserati, R.3
  • 34
    • 0037131327 scopus 로고    scopus 로고
    • Clinical use of lopinavir/ritonavir in a salvage therapy setting: Pharmacokinetics and pharmacodynamics
    • Boffito M, Arnaudo I, Raiteri R, et al. Clinical use of lopinavir/ritonavir in a salvage therapy setting: pharmacokinetics and pharmacodynamics. AIDS 2002; 16:2081-3.
    • (2002) AIDS , vol.16 , pp. 2081-2083
    • Boffito, M.1    Arnaudo, I.2    Raiteri, R.3
  • 35
    • 0035253297 scopus 로고    scopus 로고
    • Phenotypic drug susceptibility testing predicts long-term virologic suppression better than treatment history in patients with human immunodeficiency virus infection
    • Call SA, Saag MS, Westfall AO, et al. Phenotypic drug susceptibility testing predicts long-term virologic suppression better than treatment history in patients with human immunodeficiency virus infection. J Infect Dis 2001; 183:401-8.
    • (2001) J Infect Dis , vol.183 , pp. 401-408
    • Call, S.A.1    Saag, M.S.2    Westfall, A.O.3
  • 36
    • 0034232576 scopus 로고    scopus 로고
    • A Clinical study of the combination of 100 mg ritonavir plus 800 mg indinavir as salvage therapy: Influence of increased plasma drug levels in the rate of response
    • Casado JL, Moreno A, Sabido R, et al. A Clinical study of the combination of 100 mg ritonavir plus 800 mg indinavir as salvage therapy: influence of increased plasma drug levels in the rate of response. HIV Clin Trials 2000; 1:13-9.
    • (2000) HIV Clin Trials , vol.1 , pp. 13-19
    • Casado, J.L.1    Moreno, A.2    Sabido, R.3
  • 37
    • 0037016433 scopus 로고    scopus 로고
    • Plasma drug levels, genotypic resistance, and virological response to a nelfinavir plus saquinavir-containing regimen
    • Casado JL, Moreno S, Hertogs K, et al. Plasma drug levels, genotypic resistance, and virological response to a nelfinavir plus saquinavir-containing regimen. AIDS 2002; 16:47-52.
    • (2002) AIDS , vol.16 , pp. 47-52
    • Casado, J.L.1    Moreno, S.2    Hertogs, K.3
  • 38
    • 0034785291 scopus 로고    scopus 로고
    • Randomized salvage therapy with saquinavir-ritonavir versus saquinavir-nelfinavir for highly protease inhibitor-experienced HIV-infected patients
    • Chavanet P, Piroth L, Grappin M, et al. Randomized salvage therapy with saquinavir-ritonavir versus saquinavir-nelfinavir for highly protease inhibitor-experienced HIV-infected patients. HIV Clin Trials 2001; 2:408-12.
    • (2001) HIV Clin Trials , vol.2 , pp. 408-412
    • Chavanet, P.1    Piroth, L.2    Grappin, M.3
  • 39
    • 0035986072 scopus 로고    scopus 로고
    • Salvage treatment with lopinavir/ritonavir (Kaletra) in HIV-infected patients failing all current antiretroviral drug families
    • de Mendoza C, Martin-Carbonero L, Barreiro P, et al. Salvage treatment with lopinavir/ritonavir (Kaletra) in HIV-infected patients failing all current antiretroviral drug families. HIV Clin Trials 2002; 3:304-9.
    • (2002) HIV Clin Trials , vol.3 , pp. 304-309
    • De Mendoza, C.1    Martin-Carbonero, L.2    Barreiro, P.3
  • 40
    • 0035451103 scopus 로고    scopus 로고
    • Extent of human immunodeficiency virus type 1 drug resistance as a predictor of virological failure after genotype-guided treatment switch
    • Dionisio D, Vivarelli A, Zazzi M, Esperti F, Uberti M, Polidori M. Extent of human immunodeficiency virus type 1 drug resistance as a predictor of virological failure after genotype-guided treatment switch. Clin Infect Dis 2001; 33:706-9.
    • (2001) Clin Infect Dis , vol.33 , pp. 706-709
    • Dionisio, D.1    Vivarelli, A.2    Zazzi, M.3    Esperti, F.4    Uberti, M.5    Polidori, M.6
  • 41
    • 0032842750 scopus 로고    scopus 로고
    • Salvage therapy with regimens containing ritonavir and saquinavir in extensively pretreated HIV-infected patients
    • Fatkenheuer G, Hoetelmans RM, Hunn N, et al. Salvage therapy with regimens containing ritonavir and saquinavir in extensively pretreated HIV-infected patients. AIDS 1999; 13:1485-9.
    • (1999) AIDS , vol.13 , pp. 1485-1489
    • Fatkenheuer, G.1    Hoetelmans, R.M.2    Hunn, N.3
  • 42
    • 0037083807 scopus 로고    scopus 로고
    • HIV-1 genotype and phenotype correlate with virological response to abacavir, amprenavir and efavirenz in treatment-experienced patients
    • Falloon J, Ait-Khaled M, Thomas DA, et al. HIV-1 genotype and phenotype correlate with virological response to abacavir, amprenavir and efavirenz in treatment-experienced patients. AIDS 2002; 16:387-96.
    • (2002) AIDS , vol.16 , pp. 387-396
    • Falloon, J.1    Ait-Khaled, M.2    Thomas, D.A.3
  • 43
    • 0034949158 scopus 로고    scopus 로고
    • Combination therapy with indinavir, ritonavir, and delavirdine and nucleoside reverse transcriptase inhibitors in patients with HIV/AIDS who have failed multiple antiretroviral combinations
    • Grodesky M, Acosta EP, Fujita N, Mason S, Gerber JG. Combination therapy with indinavir, ritonavir, and delavirdine and nucleoside reverse transcriptase inhibitors in patients with HIV/AIDS who have failed multiple antiretroviral combinations. HIV Clin Trials 2001; 2:193-9.
    • (2001) HIV Clin Trials , vol.2 , pp. 193-199
    • Grodesky, M.1    Acosta, E.P.2    Fujita, N.3    Mason, S.4    Gerber, J.G.5
  • 44
    • 0035882308 scopus 로고    scopus 로고
    • Initial virological and immunologic response to highly active antiretroviral therapy predicts long-term clinical outcome
    • Kitchen CM, Kitchen SG, Dubin JA, Gottlieb MS. Initial virological and immunologic response to highly active antiretroviral therapy predicts long-term clinical outcome. Clin Infect Dis 2001; 33:466-72.
    • (2001) Clin Infect Dis , vol.33 , pp. 466-472
    • Kitchen, C.M.1    Kitchen, S.G.2    Dubin, J.A.3    Gottlieb, M.S.4
  • 45
    • 0033550965 scopus 로고    scopus 로고
    • Clinical progression and virological failure on highly active antiretroviral therapy in HIV-1 patients: A prospective cohort study. Swiss HIV Cohort Study
    • Ledergerber B, Egger M, Opravil M, et al. Clinical progression and virological failure on highly active antiretroviral therapy in HIV-1 patients: a prospective cohort study. Swiss HIV Cohort Study. Lancet 1999; 353:863-8.
    • (1999) Lancet , vol.353 , pp. 863-868
    • Ledergerber, B.1    Egger, M.2    Opravil, M.3
  • 46
    • 0033009094 scopus 로고    scopus 로고
    • Impact of drug resistance mutations on virologic response to salvage therapy. Swiss HIV Cohort Study
    • Lorenzi P, Opravil M, Hirschel B, et al. Impact of drug resistance mutations on virologic response to salvage therapy. Swiss HIV Cohort Study. AIDS 1999; 13:F17-21.
    • (1999) AIDS , vol.13
    • Lorenzi, P.1    Opravil, M.2    Hirschel, B.3
  • 47
    • 0035013919 scopus 로고    scopus 로고
    • Limits of deep salvage antiretroviral therapy with nelfinavir plus either efavirenz or nevirapine, in highly pre-treated patients with HIV disease
    • Manfredi R, Chiodo F. Limits of deep salvage antiretroviral therapy with nelfinavir plus either efavirenz or nevirapine, in highly pre-treated patients with HIV disease. Int J Antimicrob Agents 2001; 17:511-6.
    • (2001) Int J Antimicrob Agents , vol.17 , pp. 511-516
    • Manfredi, R.1    Chiodo, F.2
  • 48
    • 0034795384 scopus 로고    scopus 로고
    • The use of efavirenz as a part of late rescue antiretroviral treatment
    • Manfredi R, Rizzo E, Calza L, Chiodo F. The use of efavirenz as a part of late rescue antiretroviral treatment. HIV Clin Trials 2001; 2:413-20.
    • (2001) HIV Clin Trials , vol.2 , pp. 413-420
    • Manfredi, R.1    Rizzo, E.2    Calza, L.3    Chiodo, F.4
  • 49
    • 0037347966 scopus 로고    scopus 로고
    • Prospective comparison of first-line nelfinavir therapy versus nelfinavir introduction in rescue antiretroviral regimens
    • Manfredi R, Calza L, Chiodo F. Prospective comparison of first-line nelfinavir therapy versus nelfinavir introduction in rescue antiretroviral regimens. AIDS Patient Care STDS 2003; 17:105-14.
    • (2003) AIDS Patient Care STDS , vol.17 , pp. 105-114
    • Manfredi, R.1    Calza, L.2    Chiodo, F.3
  • 50
    • 0035951502 scopus 로고    scopus 로고
    • The use of and response to second-line protease inhibitor regimens: Results from the EuroSIDA study
    • Mocroft A, Phillips AN, Miller V, et al. The use of and response to second-line protease inhibitor regimens: results from the EuroSIDA study. AIDS 2001; 15:201-9.
    • (2001) AIDS , vol.15 , pp. 201-209
    • Mocroft, A.1    Phillips, A.N.2    Miller, V.3
  • 51
    • 0036192999 scopus 로고    scopus 로고
    • Nevirapine + efavirenz based salvage therapy in heavily pretreated HIV infected patients
    • Olivieri J. Nevirapine + efavirenz based salvage therapy in heavily pretreated HIV infected patients. Sex Transm Infect 2002; 78:72-3.
    • (2002) Sex Transm Infect , vol.78 , pp. 72-73
    • Olivieri, J.1
  • 52
    • 0034013992 scopus 로고    scopus 로고
    • Quantification of the impact of HIV-1 reverse transcriptase and protease mutations on the efficacy of rescue HAART
    • Paolucci S, Baldanti F, Maserati R, et al. Quantification of the impact of HIV-1 reverse transcriptase and protease mutations on the efficacy of rescue HAART. Antiviral Res 2000; 45:101-14.
    • (2000) Antiviral Res , vol.45 , pp. 101-114
    • Paolucci, S.1    Baldanti, F.2    Maserati, R.3
  • 53
    • 0037103631 scopus 로고    scopus 로고
    • Treatment with lopinavir/ritonavir in heavily pretreated subjects failing multiple antiretroviral regimens in clinical practice
    • Romano L, Peduzzi C, Venturi G, et al. Treatment with lopinavir/ritonavir in heavily pretreated subjects failing multiple antiretroviral regimens in clinical practice. J Acquir Immune Defic Syndr 2002; 30:533-5.
    • (2002) J Acquir Immune Defic Syndr , vol.30 , pp. 533-535
    • Romano, L.1    Peduzzi, C.2    Venturi, G.3
  • 54
    • 0035292151 scopus 로고    scopus 로고
    • Virological response in multidrug-experienced HIV-1-infected subjects failing highly active combination regimens after shifting from lamivudine to didanosine
    • Rusconi S, La Seta Catamancio S, Citterio P, et al. Virological response in multidrug-experienced HIV-1-infected subjects failing highly active combination regimens after shifting from lamivudine to didanosine. Antivir Ther 2001; 6:41-6.
    • (2001) Antivir Ther , vol.6 , pp. 41-46
    • Rusconi, S.1    La Seta Catamancio, S.2    Citterio, P.3
  • 55
    • 0345701517 scopus 로고    scopus 로고
    • Treatment with indinavir, efavirenz, and adefovir after failure of nelfinavir therapy
    • Saah AJ, Haas DW, DiNubile MJ, et al. Treatment with indinavir, efavirenz, and adefovir after failure of nelfinavir therapy. J Infect Dis 2003; 187:1157-62.
    • (2003) J Infect Dis , vol.187 , pp. 1157-1162
    • Saah, A.J.1    Haas, D.W.2    DiNubile, M.J.3
  • 56
    • 0035046656 scopus 로고    scopus 로고
    • A randomized trial of nelfinavir, ritonavir, or delavirdine in combination with saquinavir-SGC and stavudine in treatment-experienced HIV-1-infected patients
    • Smith D, Hales G, Roth N, et al. A randomized trial of nelfinavir, ritonavir, or delavirdine in combination with saquinavir-SGC and stavudine in treatment-experienced HIV-1-infected patients. HIV Clin Trials 2001; 2:97-107.
    • (2001) HIV Clin Trials , vol.2 , pp. 97-107
    • Smith, D.1    Hales, G.2    Roth, N.3
  • 57
    • 0037183919 scopus 로고    scopus 로고
    • Impact of HIV genotyping and drug levels on the response to salvage therapy with saquinavir/ritonavir
    • Valer L, De Mendoza C, De Requena DG, et al. Impact of HIV genotyping and drug levels on the response to salvage therapy with saquinavir/ritonavir. AIDS 2002; 16:1964-6.
    • (2002) AIDS , vol.16 , pp. 1964-1966
    • Valer, L.1    De Mendoza, C.2    De Requena, D.G.3
  • 58
    • 0035902910 scopus 로고    scopus 로고
    • Non-nucleoside reverse transcriptase inhibitor failure impairs HIV-RNA responses to efavirenz-containing salvage antiretroviral therapy
    • Walmsley SL, Kelly DV, Tseng AL, Humar A, Harrigan PR. Non-nucleoside reverse transcriptase inhibitor failure impairs HIV-RNA responses to efavirenz-containing salvage antiretroviral therapy. AIDS 2001; 15:1581-4.
    • (2001) AIDS , vol.15 , pp. 1581-1584
    • Walmsley, S.L.1    Kelly, D.V.2    Tseng, A.L.3    Humar, A.4    Harrigan, P.R.5
  • 59
    • 0037013094 scopus 로고    scopus 로고
    • Efficacy and safety of abacavir plus efavirenz as a salvage regimen in HIV-infected individuals after 48 weeks
    • Wasmuth JC, Herhaus C, Romer K, et al. Efficacy and safety of abacavir plus efavirenz as a salvage regimen in HIV-infected individuals after 48 weeks. AIDS 2002; 16:1077-8.
    • (2002) AIDS , vol.16 , pp. 1077-1078
    • Wasmuth, J.C.1    Herhaus, C.2    Romer, K.3
  • 60
    • 0036153694 scopus 로고    scopus 로고
    • Brief report: Two-year outcome of a multidrug regimen in patients who did not respond to a protease inhibitor regimen
    • Youle M, Tyrer M, Fisher M, et al. Brief report: two-year outcome of a multidrug regimen in patients who did not respond to a protease inhibitor regimen. J Acquir Immune Defic Syndr 2002; 29:58-61.
    • (2002) J Acquir Immune Defic Syndr , vol.29 , pp. 58-61
    • Youle, M.1    Tyrer, M.2    Fisher, M.3
  • 61
    • 0036097178 scopus 로고    scopus 로고
    • Salvage therapy with amprenavir and ritonavir: Prospective study in 17 heavily pretreated patients
    • Arvieux C, Tattevin P, Souala FM, et al. Salvage therapy with amprenavir and ritonavir: prospective study in 17 heavily pretreated patients. HIV Clin Trials 2002; 3:125-32.
    • (2002) HIV Clin Trials , vol.3 , pp. 125-132
    • Arvieux, C.1    Tattevin, P.2    Souala, F.M.3
  • 62
    • 0037083803 scopus 로고    scopus 로고
    • Usefulness of monitoring HIV drug resistance and adherence in individuals failing highly active antiretroviral therapy: A randomized study (ARGENTA)
    • Cingolani A, Antinori A, Rizzo MG, et al. Usefulness of monitoring HIV drug resistance and adherence in individuals failing highly active antiretroviral therapy: a randomized study (ARGENTA). AIDS 2002; 16:369-79.
    • (2002) AIDS , vol.16 , pp. 369-379
    • Cingolani, A.1    Antinori, A.2    Rizzo, M.G.3
  • 63
    • 0034104090 scopus 로고    scopus 로고
    • Efficacy, safety, and adherence with a twice-daily combination lamivudine/zidovudine tablet formulation, plus a protease inhibitor, in HIV infection
    • Eron JJ, Yetzer ES, Ruane PJ, et al. Efficacy, safety, and adherence with a twice-daily combination lamivudine/zidovudine tablet formulation, plus a protease inhibitor, in HIV infection. AIDS 2000; 14:671-81.
    • (2000) AIDS , vol.14 , pp. 671-681
    • Eron, J.J.1    Yetzer, E.S.2    Ruane, P.J.3
  • 64
    • 0035282645 scopus 로고    scopus 로고
    • Indinavir, nevirapine, stavudine, and lamivudine for human immunodeficiency virus-infected, amprenavir-experienced subjects: AIDS Clinical Trials Group protocol 373
    • Gulick RM, Smeaton LM, D'Aquila RT, et al. Indinavir, nevirapine, stavudine, and lamivudine for human immunodeficiency virus-infected, amprenavir-experienced subjects: AIDS Clinical Trials Group protocol 373. J Infect Dis 2001; 183:715-21.
    • (2001) J Infect Dis , vol.183 , pp. 715-721
    • Gulick, R.M.1    Smeaton, L.M.2    D'Aquila, R.T.3
  • 65
    • 0035253459 scopus 로고    scopus 로고
    • Therapy with efavirenz plus indinavir in patients with extensive prior nucleoside reverse-transcriptase inhibitor experience: A randomized, double-blind, placebo-controlled trial
    • Haas DW, Fessel WJ, Delapenha RA, et al. Therapy with efavirenz plus indinavir in patients with extensive prior nucleoside reverse-transcriptase inhibitor experience: a randomized, double-blind, placebo-controlled trial. J Infect Dis 2001; 183:392-400.
    • (2001) J Infect Dis , vol.183 , pp. 392-400
    • Haas, D.W.1    Fessel, W.J.2    Delapenha, R.A.3
  • 66
    • 0037661234 scopus 로고    scopus 로고
    • Therapy with atazanavir plus saquinavir in patients failing highly active antiretroviral therapy: A randomized comparative pilot trial
    • Haas DW, Zala C, Schrader S, et al. Therapy with atazanavir plus saquinavir in patients failing highly active antiretroviral therapy: a randomized comparative pilot trial. AIDS 2003; 17:1339-49.
    • (2003) AIDS , vol.17 , pp. 1339-1349
    • Haas, D.W.1    Zala, C.2    Schrader, S.3
  • 67
    • 0034785276 scopus 로고    scopus 로고
    • Evaluation of an efavirenz-containing regimen: An open-label, multicenter study
    • Hartmann M, Rump A, Brust J, et al. Evaluation of an efavirenz-containing regimen: an open-label, multicenter study. HIV Clin Trials 2001; 2:421-8.
    • (2001) HIV Clin Trials , vol.2 , pp. 421-428
    • Hartmann, M.1    Rump, A.2    Brust, J.3
  • 68
    • 0037849954 scopus 로고    scopus 로고
    • Efficacy of enfuvirtide in patients infected with drug-resistant HIV-1 in Europe and Australia
    • Lazzarin A, Clotet B, Cooper D, et al. Efficacy of enfuvirtide in patients infected with drug-resistant HIV-1 in Europe and Australia. N Engl J Med 2003; 348:2186-95.
    • (2003) N Engl J Med , vol.348 , pp. 2186-2195
    • Lazzarin, A.1    Clotet, B.2    Cooper, D.3
  • 69
    • 17544379494 scopus 로고    scopus 로고
    • HIV drug susceptibility and treatment response to mega-HAART regimen in patients from the Frankfurt HIV cohort
    • Miller V, Cozzi-Lepri A, Hertogs K, et al. HIV drug susceptibility and treatment response to mega-HAART regimen in patients from the Frankfurt HIV cohort. Antivir Ther 2000; 5:49-55.
    • (2000) Antivir Ther , vol.5 , pp. 49-55
    • Miller, V.1    Cozzi-Lepri, A.2    Hertogs, K.3
  • 70
    • 2442681710 scopus 로고    scopus 로고
    • Twice-daily amprenavir 1200 mg versus amprenavir 600 mg/ritonavir 100 mg, in combination with at least 2 other antiretroviral drugs in HIV-1 infected patients
    • Nadler JP, Gathe JC Jr, Pollard RB Jr, et al. Twice-daily amprenavir 1200 mg versus amprenavir 600 mg/ritonavir 100 mg, in combination with at least 2 other antiretroviral drugs in HIV-1 infected patients. BMC Infect Dis 2003; 3:10.
    • (2003) BMC Infect Dis , vol.3 , pp. 10
    • Nadler, J.P.1    Gathe Jr., J.C.2    Pollard Jr., R.B.3
  • 71
    • 0037024752 scopus 로고    scopus 로고
    • Virologic response to nelfinavir-based regimens: Pharmacokinetics and drug resistance mutations (VIRAPHAR study)
    • Pellegrin I, Breilh D, Montestruc F, et al. Virologic response to nelfinavir-based regimens: pharmacokinetics and drug resistance mutations (VIRAPHAR study). AIDS 2002; 16:1331-40.
    • (2002) AIDS , vol.16 , pp. 1331-1340
    • Pellegrin, I.1    Breilh, D.2    Montestruc, F.3
  • 72
    • 0141631851 scopus 로고    scopus 로고
    • Drug resistance mutations and outcome of second-line treatment in patients with first-line protease inhibitor failure on nelfinavir-containing HAART
    • Roge BT, Katzenstein TL, Nielsen HL, Gerstoft J. Drug resistance mutations and outcome of second-line treatment in patients with first-line protease inhibitor failure on nelfinavir-containing HAART. HIV Med 2003; 4:38-47.
    • (2003) HIV Med , vol.4 , pp. 38-47
    • Roge, B.T.1    Katzenstein, T.L.2    Nielsen, H.L.3    Gerstoft, J.4
  • 73
    • 0033572275 scopus 로고    scopus 로고
    • Efavirenz, nelfinavir, and stavudine rescue combination therapy in HIV-1-positive patients heavily pretreated with nucleoside analogues and protease inhibitors
    • Seminari E, Maggiolo F, Villani P, et al. Efavirenz, nelfinavir, and stavudine rescue combination therapy in HIV-1-positive patients heavily pretreated with nucleoside analogues and protease inhibitors. J Acquir Immune Defic Syndr 1999; 22:453-60.
    • (1999) J Acquir Immune Defic Syndr , vol.22 , pp. 453-460
    • Seminari, E.1    Maggiolo, F.2    Villani, P.3
  • 74
    • 0034232191 scopus 로고    scopus 로고
    • Efficacy of a nelfinavir- and nevirapine-containing salvage regimen
    • Sullivan AK, Nelson MR, Shaw A, et al. Efficacy of a nelfinavir- and nevirapine-containing salvage regimen. HIV Clin Trials 2000; 1:7-12.
    • (2000) HIV Clin Trials , vol.1 , pp. 7-12
    • Sullivan, A.K.1    Nelson, M.R.2    Shaw, A.3
  • 75
    • 0035212001 scopus 로고    scopus 로고
    • Effectiveness and tolerability of nevirapine, stavudine, and lamivudine in clinical practice
    • Yozviak JL, Doerfler RE, Woodward WC. Effectiveness and tolerability of nevirapine, stavudine, and lamivudine in clinical practice. HIV Clin Trials 2001; 2:474-6.
    • (2001) HIV Clin Trials , vol.2 , pp. 474-476
    • Yozviak, J.L.1    Doerfler, R.E.2    Woodward, W.C.3
  • 76
    • 0036891417 scopus 로고    scopus 로고
    • Comparison of the efficacy, safety and predictive value of HIV genotyping using distinct ritonavir-boosted protease inhibitors
    • Barreiro P, Camino N, de Mendoza C, et al. Comparison of the efficacy, safety and predictive value of HIV genotyping using distinct ritonavir-boosted protease inhibitors. Int J Antimicrob Agents 2002; 20:438-43.
    • (2002) Int J Antimicrob Agents , vol.20 , pp. 438-443
    • Barreiro, P.1    Camino, N.2    De Mendoza, C.3
  • 77
    • 0033920318 scopus 로고    scopus 로고
    • A randomized study of antiretroviral management based on plasma genotypic antiretroviral resistance testing in patients failing therapy
    • CPCRA 046 Study Team for the Terry Beirn Community Programs for Clinical Research on AIDS
    • Baxter JD, Mayers DL, Wentworth DN, et al. A randomized study of antiretroviral management based on plasma genotypic antiretroviral resistance testing in patients failing therapy. CPCRA 046 Study Team for the Terry Beirn Community Programs for Clinical Research on AIDS. AIDS 2000; 14:F83-93.
    • (2000) AIDS , vol.14
    • Baxter, J.D.1    Mayers, D.L.2    Wentworth, D.N.3
  • 78
    • 0037165931 scopus 로고    scopus 로고
    • Both baseline HIV-1 drug resistance and antiretroviral drug levels are associated with short-term virologic responses to salvage therapy
    • Baxter JD, Merigan TC, Wentworth DN, et al. Both baseline HIV-1 drug resistance and antiretroviral drug levels are associated with short-term virologic responses to salvage therapy. AIDS 2002; 16:1131-8.
    • (2002) AIDS , vol.16 , pp. 1131-1138
    • Baxter, J.D.1    Merigan, T.C.2    Wentworth, D.N.3
  • 79
    • 0034065841 scopus 로고    scopus 로고
    • Persisting long-term benefit of genotype-guided treatment for HIV-infected patients failing HAART. The Viradapt Study: Week 48 follow-up
    • Clevenbergh P, Durant J, Halfon P, et al. Persisting long-term benefit of genotype-guided treatment for HIV-infected patients failing HAART. The Viradapt Study: week 48 follow-up. Antivir Ther 2000; 5:65-70.
    • (2000) Antivir Ther , vol.5 , pp. 65-70
    • Clevenbergh, P.1    Durant, J.2    Halfon, P.3
  • 80
    • 0033942065 scopus 로고    scopus 로고
    • Importance of protease inhibitor plasma levels in HIV-infected patients treated with genotypic-guided therapy: Pharmacological data from the Viradapt Study
    • Durant J, Clevenbergh P, Garraffo R, et al. Importance of protease inhibitor plasma levels in HIV-infected patients treated with genotypic-guided therapy: pharmacological data from the Viradapt Study. AIDS 2000; 14:1333-9.
    • (2000) AIDS , vol.14 , pp. 1333-1339
    • Durant, J.1    Clevenbergh, P.2    Garraffo, R.3
  • 81
    • 0037320996 scopus 로고    scopus 로고
    • Effect of therapeutic drug monitoring on outcome in antiretroviral experienced HIV-infected individuals
    • Mallon PW, Ray J, Cooper DA. Effect of therapeutic drug monitoring on outcome in antiretroviral experienced HIV-infected individuals. J Clin Virol 2003; 26:223-7.
    • (2003) J Clin Virol , vol.26 , pp. 223-227
    • Mallon, P.W.1    Ray, J.2    Cooper, D.A.3
  • 82
    • 0037340710 scopus 로고    scopus 로고
    • Real versus virtual phenotype to guide treatment in heavily pretreated patients: 48-Week follow-up of the Genotipo-Fenotipo di Resistenza (GenPheRex) trial
    • Mazzotta F, Lo Caputo S, Torti C, et al. Real versus virtual phenotype to guide treatment in heavily pretreated patients: 48-week follow-up of the Genotipo-Fenotipo di Resistenza (GenPheRex) trial. J Acquir Immune Defic Syndr 2003; 32:268-80.
    • (2003) J Acquir Immune Defic Syndr , vol.32 , pp. 268-280
    • Mazzotta, F.1    Lo Caputo, S.2    Torti, C.3
  • 83
    • 0035020615 scopus 로고    scopus 로고
    • Long-term benefit of genotypic-guided therapy and prevalence of multinucleoside resistance in an Italian group of antiretroviral multiexperienced patients
    • Quiros-Roldan E, Moretti F, Airoldi M, et al. Long-term benefit of genotypic-guided therapy and prevalence of multinucleoside resistance in an Italian group of antiretroviral multiexperienced patients. J Clin Lab Anal 2001; 15:127-30.
    • (2001) J Clin Lab Anal , vol.15 , pp. 127-130
    • Quiros-Roldan, E.1    Moretti, F.2    Airoldi, M.3
  • 84
    • 0036720473 scopus 로고    scopus 로고
    • Durability of response to treatment among antiretroviral-experienced subjects: 48-Week results from AIDS Clinical Trials Group Protocol 359
    • Gulick RM, Hu XJ, Fiscus SA, et al. Durability of response to treatment among antiretroviral-experienced subjects: 48-week results from AIDS Clinical Trials Group Protocol 359. J Infect Dis 2002; 186:626-33.
    • (2002) J Infect Dis , vol.186 , pp. 626-633
    • Gulick, R.M.1    Hu, X.J.2    Fiscus, S.A.3
  • 85
    • 0034521513 scopus 로고    scopus 로고
    • Loss of antiretroviral drug susceptibility at low viral load during early virological failure in treatment-experienced patients
    • Parkin NT, Deeks SG, Wrin MT, et al. Loss of antiretroviral drug susceptibility at low viral load during early virological failure in treatment-experienced patients. AIDS 2000; 14:2877-87.
    • (2000) AIDS , vol.14 , pp. 2877-2887
    • Parkin, N.T.1    Deeks, S.G.2    Wrin, M.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.