Protein kinase a phosphorylates serine 267 in the homeodomain of engrailed-2 leading to decreased DNA binding

FEBS Letters

Volumn 568, Issue 1-3, 2004, Pages 55-59

  Hjerrild, Majbrit ^a   Stensballe, Allan ^b   Jensen, Ole N ^b   Gammeltoft, Steen ^a   Rasmussen, Thomas E ^a  

^a GLOSTRUP UNIVERSITY HOSPITAL   (Denmark)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

DNA binding; DTT, dithiotreitol; En 2, engrailed 2; Engrailed 2; HA tag, haemagglutinin tag; Homeodomain; LC ESI MS MS, liquid chromatography electrospray tandem mass spectrometry; PKA, protein kinase A; Protein kinase A; Protein phosphorylation

Indexed keywords

ALANINE; CYCLIC AMP DEPENDENT PROTEIN KINASE; DNA; DNA BINDING PROTEIN; ENGRAILED 2 PROTEIN; GLUTAMIC ACID; HOMEODOMAIN PROTEIN; PHOSPHOPROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL STRAIN COS7; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION;

AMINO ACID SEQUENCE; ANIMALS; CELL NUCLEUS; COS CELLS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DNA; HOMEODOMAIN PROTEINS; NERVE TISSUE PROTEINS; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); PROTEIN BINDING;

MAMMALIA;

EID: 2942589057     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2004.05.009     Document Type: Article

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