Animal models of depression: Olfactory lesions affect amygdala, subventricular zone, and aggression

Neurobiology of Disease

Volumn 16, Issue 2, 2004, Pages 386-395

  Mucignat Caretta, Carla ^a   Bondi', Michela ^a   Caretta, Antonio ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

Aggression; Behavior; Depression; Neural stem cells; Olfactory bulbectomy; Rostral migratory stream

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE;

AGGRESSIVENESS; AMYGDALOID NUCLEUS; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATYPICAL DEPRESSION; CONTROLLED STUDY; DISSOCIATIVE DISORDER; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; MUCOSAL NECROSIS; NEUROANATOMY; NEUROMODULATION; NONHUMAN; OLFACTORY BULBECTOMY; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; SENSORY DEPRIVATION; SENSORY DYSFUNCTION; SOCIAL INTERACTION;

AGGRESSION; AMYGDALA; ANIMALS; ANXIETY DISORDERS; BEHAVIOR, ANIMAL; DENERVATION; DEPRESSIVE DISORDER; DISEASE MODELS, ANIMAL; MALE; MICE; OLFACTORY BULB; STEM CELLS;

EID: 2942585130     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2004.03.007     Document Type: Article

References (59)

1. Arnold S.E., Han L.Y., Moberg P.J., Turetsky B.I., Gur R.E., Trojanowski J.Q., Hahn C.G. Dysregulation of olfactory receptor neuron lineage in schizophrenia. Arch. Gen. Psychiatry. 58:2001;829-835
2. Bobkova N.V., Nesterova I.V., Nesterov V.V. The state of cholinergic structures in forebrain of bulbectomized mice. Bull. Exp. Biol. Med. 131:2001;427-431
3. Bouwmeester H., Wolterink G., van Ree J.M. Neonatal development of projections from the basolateral amygdala to prefrontal, striatal, and thalamic structures in the rat. J. Comp. Neurol. 442:2002;239-249
4. Brunjes P.C. Lessons from lesions: the effects of olfactory bulbectomy. Chem. Senses. 17:1992;729-763
5. Burd G.D. Morphological study of the effects of intranasal zinc sulfate irrigation on the mouse olfactory epithelium and olfactory bulb. Microsc. Res. Tech. 24:1993;195-213
6. Cain D.P., Paxinos G. Olfactory bulbectomy and mucosal damage: effects on copulation, irritability, and interspecific effects in male rats. J. Comp. Physiol. Psychol. 86:1974;202-212
7. Deprato Primeaux S., Holmes P.V. Role of aversively motivated behavior in the olfactory bulbectomy syndrome. Physiol. Behav. 67:1999;41-47
8. Ducray A., Bondier J.R., Michel G., Bon K., Millot J.L., Propper A., Kastner A. Recovery following peripheral destruction of olfactory neurons in young and adult mice. Eur. J. Neurosci. 15:2002;1907-1917
9. Edwards D.A., Thompson M.L., Burge K.G. Olfactory bulb removal vs. peripherally induced anosmia: differential effects on the aggressive behavior of male mice. Behav. Biol. 7:1972;823-828
10. Elwood R.W., Masterson D., O'Neill C. Protecting pups in tests for infanticidal responsiveness in mice, Mus domesticus. Anim. Behav. 40:1991;778-780
11. Ferguson J.N., Aldag J.M., Insel T.R., Young L.J. Oxytocin in the medial amygdala is essential for social recognition in the mouse. J. Neurosci. 21:2001;8278-8285
12. Fleming A., Vaccarino F., Tambosso L., Chee P. Vomeronasal and olfactory system modulation of maternal behavior in the rat. Science. 203:1979;372-374
13. Franklin K.B., Paxinos G. The Mouse Brain in Stereotaxic Coordinates. 2000;Academic Press, San Diego
14. Garris D.R., Chamberlain J.K., Davanzo J.P. Histofluorescent identification of indoleamine-concentrating brain loci associated with intraspecies, reflexive biting and locomotor behavior in olfactory bulbectomized mice. Brain Res. 294:1984;385-389
15. Graziadei P.P., Monti Graziadei G.A. Neuronal changes in the forebrain of mice following penetration by regenerating olfactory axons. J. Comp. Neurol. 247:1986;344-356
16. Halpern M., Martinez-Marcos A. Structure and function of the vomeronasal system: an update. Prog. Neurobiol. 70:2003;245-318
17. Hansen L.F., Hammer M., Petersen S.H., Nielsen G.D. Effects of intranasal ZnSO4 irrigation on olfactory and trigeminal cues. Physiol. Behav. 55:1994;699-704
18. Harding J.W., Getchell T.V., Margolis F.L. Denervation of the primary olfactory pathway in mice: V. Long-term effect of intranasal ZnSO4 irrigation on behavior, biochemistry and morphology. Brain Res. 140:1978;271-285
19. Hendricks K.R., Kott J.N., Gooden M.D., Lee M.E., Evers S.M., Goheen B.L., Westrum L.E. Recovery of olfactory behavior: II. Neonatal olfactory bulb transplants enhance the rate of behavioral recovery. Brain Res. 648:1994;135-147
20. Herzog C., Otto T. Regeneration of olfactory receptor neurons following chemical lesions: time course and enhancement with growth factor administration. Brain Res. 849:1999;155-161
21. 3H] MK-801 binding assay. Brain Res. 900:2001;214-218
22. Holmes P.V., Davis R.C., Masini C.V., Primeaux S.D. Effects of olfactory bulbectomy on neuropeptide gene expression in the rat olfactory/limbic system. Neuroscience. 86:1998;587-596
23. Jankovski A., Garcia C., Soriano E., Sotelo C. Proliferation, migration and differentiation of neuronal progenitor cells in the adult mouse subventricular zone surgically separated from its olfactory bulbs. Eur. J. Neurosci. 10:1998;3853-3868
24. Jentsch J.D., Olausson P., Nestler E.J., Taylor J.R. Stimulation of protein kinase A activity in the rat amygdala enhances reward-related learning. Biol. Psychiatry. 52:2002;111-118
25. Kelly J.P., Leonard B.E. An investigation of the antidepressant properties of lofepramine and its desmethylated metabolites in the forced swim and olfactory bulbectomized rat models of depression. Eur. Neuropsychoparmacol. 9:1999;101-105
26. Kelly J.P., Wrynn A.S., Leonard B.E. The olfactory bulbectomized rat as a model of depression: an update. Pharmacol. Ther. 74:1997;299-316
27. Kirschenbaum B., Doetsch F., Lois C., Alvarez-Buylla A. Adult subventricular zone neuronal precursors continue to proliferate and migrate in the absence of the olfactory bulb. J. Neurosci. 19:1999;2171-2180
28. Lawrie S.M., Whalley H., Kestelman J.N., Abukmeil S.S., Byrne M., Hodges A., Rimmington J.E., Best J.J., Owens D.G., Johnstone E.C. Magnetic resonance imaging of brain in people at high risk of developing schizophrenia. Lancet. 353:1999;30-33
29. Leonard B.E., Tuite M. Anatomical, physiological, and behavioral aspects of olfactory bulbectomy in the rat. Int. Rev. Neurobiol. 22:1981;251-286
30. Liebenauer L.L., Slotnick B.M. Social organization and aggression in a group of olfactory bulbectomized male mice. Physiol. Behav. 60:1996;403-409
31. 3H]cAMP binding sites are unaltered in depressed suicides, but decreased by antidepressants. Brain Res. 758:1997;223-228
32. Lucki I., Dalvi A., Mayorga A.J. Sensitivity to the effects of pharmacologically selective antidepressants in different strains of mice. Psychopharmacology. 155:2001;315-322
33. Lumia A.R., Teicher M.H., Salchli F., Ayers E., Possidente B. Olfactory bulbectomy as a model for agitated hyposerotoninergic depression. Brain Res. 587:1992;181-185
34. Luskin M.B. Restricted proliferation and migration of postnatally generated neurons derived from the forebrain subventricular zone. Neuron. 11:1993;173-189
35. Mayer A.D., Rosenblatt J.S. Peripheral olfactory deafferentation of the primary olfactory system in rats using ZnSO4 nasal spray with special reference to maternal behavior. Physiol. Behav. 53:1993;587-592
36. McBride K., Slotnick B., Margolis F.L. Does intranasal application of zinc sulfate produce anosmia in the mouse? An olfactometric and anatomical study. Chem. Senses. 28:2003;659-670
37. McCarley R.W., Wible C.G., Frumin M., Hirayasu Y., Levitt J.J., Fischer I.A., Shenton M.E. MRI anatomy of schizophrenia. Biol. Psychiatry. 45:1999;1099-1119
38. Moffitt J.A., Grippo A.J., Holmes P.V., Johnson A.K. Olfactory bulbectomy attenuates cardiovascular sympathoexcitatory reflexes in rats. Am. J. Physiol.: Heart Circ. Physiol. 283:2002;H2575-H2583
39. Moita M.A., Lamprecht R., Nader K., Le Doux J.E. A-kinase anchoring proteins in amygdala are involved in auditory fear memory. Nat. Neurosci. 5:2002;837-838
40. Monti-Graziadei A.G., Graziadei P.P.C. Sensory reinnervation after partial removal of the olfactory bulb. J. Comp. Neurol. 316:1992;32-44
41. Mucignat-Caretta C., Caretta A. Localization of Triton-insoluble cAMP-dependent kinase type RIbeta in rat and mouse brain. J. Neurocytol. 30:2001;885-894
42. Mucignat-Caretta C., Caretta A. Clustered distribution of cAMP-dependent protein kinase regulatory isoform RIα during the development of the rat brain. J. Comp. Neurol. 451:2002;324-333
43. Nestler E.J., Barrot M., Di Leone R.J., Eisch A.J., Gold S.J., Monteggia L.M. Neurobiology of depression. Neuron. 34:2002;13-25
44. Pause B.M., Miranda A., Goder R., Aldenhoff J.B., Ferstl R. Reduced olfactory performance in patients with major depression. J. Psychiatr. Res. 35:2001;271-277
45. Porsolt R.D., Le Pichon M., Jalfre M. Depression: a new animal model sensitive to antidepressant treatments. Nature. 266:1977;730-732
46. Robichaud M., Beauchemin V., Lavoie N., Dennis T., Debonnel G. Effects of bilateral olfactory bulbectomy on N-methyl-D-aspartate receptor function: autoradiographic and behavioral studies in the rat. Synapse. 42:2001;95-103
47. Siegle G.J., Steinhauer S.R., Thase M.E., Stenger V.A., Carter C.S. Can't shake that feeling: event-related fMRI assessment of sustained amygdala activity in response to emotional information in depressed individuals. Biol. Psychiatry. 51:2002;693-707
48. Slotnick B.M., Gutman L.A. Evaluation of intranasal zinc sulfate treatment on olfactory discrimination in rats. J. Comp. Physiol. Psychol. 91:1977;942-950
49. Stock H.S., Ford K., Wilson M.A. Gender and gonadal hormone effects in the olfactory bulbectomy animal model of depression. Pharmacol. Biochem. Behav. 67:2000;183-191
50. Stock H.S., Hand G.A., Ford K., Wilson M.A. Changes in defensive behaviors following olfactory bulbectomy in male and female rats. Brain Res. 903:2001;242-246
51. Sun T.J., Miller M.L., Hastings L. Effects of inhalation of cadmium on the rat olfactory system: behavior and morphology. Neurotoxicol. Teratol. 18:1996;89-98
52. Tebartz van Elst L., Baeumer D., Lemieux L., Woermann F.G., Koepp M., Krishnamoorthy S., Thompson P.J., Ebert D., Trimble M.R. Amygdala pathology in psychosis of epilepsy: a magnetic resonance imaging study in patients with temporal lobe epilepsy. Brain. 125:2002;140-149
53. Tiffany P.B., Mollenauer S., Plotnik R., White M. Olfactory bulbectomy: emotional behavior and defense responses in the rat. Physiol. Behav. 22:1979;311-317
54. van Riezen H., Schnieden H., Wren A.F. Olfactory bulb ablation in the rat: behavioural changes and their reversal by antidepressant drugs. Br. J. Pharmacol. 60:1977;21-528
55. van Riezen H., Leonard B.E. Effects of psychotropic drugs on the behavior and neurochemistry of olfactory bulbectomized rats. Pharmacol. Ther. 47:1990;21-34
56. Webster H.H., Flores G., Marcotte E.R., Cecyre D., Quirion R., Srivastava L.K. Olfactory bulbectomy alters NMDA receptor levels in the rat prefrontal cortex. Synapse. 37:2000;159-162
57. Winner B., Cooper-Kuhn C.M., Aigner R., Winkler J., Kuhn H.G. Long-term survival and cell death of newly generated neurons in the adult rat olfactory bulb. Eur. J. Neurosci. 16:2002;1681-1689
58. Wrynn A.S., Sebens J.B., Koch T., Leonard B.E., Korf J. Prolonged c-Jun expression in the basolateral amygdala following bulbectomy: possible implications for anti depressant activity and time of onset. Mol. Brain Res. 76:2000;7-17
59. Zigova T., Amemori T., Racekova E., Marsala J. Atypical glomerulization in the remnants of the olfactory bulb after bulbectomy. A light microscopic study. J. Hirnforsch. 29:1988;217-220