Relationships between bone mass and circulating leptin concentrations in Hutterites

Bone

Volumn 34, Issue 6, 2004, Pages 1017-1022

  Wosje, Karen S ^a   Binkley, Teresa L ^a   Kalkwarf, Heidi J ^b   Specker, Bonny L ^a  

^a SOUTH DAKOTA STATE UNIVERSITY   (United States)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

Bone density; Bone mass; Bone mineral content; Hutterite; Leptin

Indexed keywords

LEPTIN;

ADULT; AGE DISTRIBUTION; ARTICLE; BODY FAT; BONE MASS; BONE MINERAL; CONTROLLED STUDY; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; FEMUR NECK; HIP; HUMAN; LUMBAR VERTEBRA; MALE; PROTEIN BLOOD LEVEL; SEX DIFFERENCE; STATISTICAL ANALYSIS;

ADULT; ANALYSIS OF VARIANCE; BODY MASS INDEX; BODY WEIGHT; BONE DENSITY; FEMALE; HUMANS; LEPTIN; MALE; MIDDLE AGED; REGRESSION ANALYSIS; SOUTH DAKOTA;

EID: 2942568378     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2004.01.006     Document Type: Article

References (23)

1. Wosje K.S., Binkley T.L., Fahrenwald N.L., Specker B.L. High bone mass in a female Hutterite population. J. Bone Miner. Res. 15:2000;1429-1436
2. Matkovic V., Ilich J.Z., Skugor M., Badenhop N.E., Goel P., Clairmont A., et al. Leptin is inversely related to age at menarche in human females. J. Clin. Endocrinol. Metab. 82:1997;3239-3245
3. Goulding A., Taylor R.W. Plasma leptin values in relation to bone mass and density and to dynamic biochemical markers of bone resorption and formation in postmenopausal women. Calcif. Tissue Int. 63:1998;456-458
4. Halaas J.L., Gajiwala K.S., Maffei M., Cohen S.L., Chait B.T., Rabinowitz D., et al. Weight-reducing effects of the plasma protein encoded by the obese gene. Science. 269:1995;543-546
5. Ducy P., Amling M., Takeda S., Priemel M., Schilling A.F., Beil F.T., et al. Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass. Cell. 100:2000;197-207
6. Odabasi E., Ozata M., Turan M., Bingol N., Yonem A., Cakir B., et al. Plasma leptin concentrations in postmenopausal women with osteoporosis. Eur. J. Endocrinol. 142:2000;170-173
7. Felson D.T., Zhang Y., Hannan M.T., Anderson J.J. Effects of weight and body mass index on bone mineral density in men and women: the Framingham study. J. Bone Miner. Res. 8:1993;567-573
8. Harris S., Dallal G.E., Dawson-Hughes B. Influence of body weight on rates of change in bone density of the spine, hip, and radius in postmenopausal women. Calcif. Tissue Int. 50:1992;19-23
9. Tremollieres F.A., Pouilles J.M., Ribot C. Vertebral post-menopausal bone loss is reduced in overweight women: a longitudinal study in 155 early postmenopausal women. J. Clin. Endocrinol. Metab. 77:1993;683-686
10. Frost H.M. On our age-related bone loss: insights from a new paradigm. J. Bone Miner. Res. 12:1997;1539-1546
11. Blum M., Harris S.S., Must A., Naumova E.N., Phillips S.M., Rand W.M., et al. Leptin, body composition and bone mineral density in premenopausal women. Calcif. Tissue Int. 2003;. [epub ahead of print]
12. Pasco J.A., Henry M.J., Kotowicz M.A., Collier G.R., Ball M.J., Ugoni A.M., et al. Serum leptin levels are associated with bone mass in nonobese women. J. Clin. Endocrinol. Metab. 86:2001;1884-1887
13. Thomas T., Burguera B., Melton L.J. III, Atkinson E.J., O'Fallon W.M., Riggs B.L., et al. Role of serum leptin, insulin, and estrogen levels as potential mediators of the relationship between fat mass and bone mineral density in men versus women. Bone. 29:2001;114-120
14. Ruhl C.E., Everhart J.E. Relationship of serum leptin concentration with bone mineral density in the United States population. J. Bone Miner. Res. 17:2002;1896-1903
15. Blair S.N., Haskel W.L., Ho P., Paffenbarger R.S., Farquhar J.W., Wood P. Assessment of habitual physical activity by a 7-day recall in a community survey and controlled experiments. Am. J. Epidemiol. 122:1985;790-804
16. Banks W.A., Farrell C.L. Impaired transport of leptin across the blood-brain barrier in obesity is acquired and reversible. Am. J. Physiol.: Endocrinol. Metab. 285:2003;E10-E15
17. Nindl B.C., Scoville C.R., Sheehan K.M., Leone C.D., Mello R.P. Gender differences in regional body composition and somatotrophic influences of IGF-I and leptin. J. Appl. Physiol. 92:2002;1611-1618
18. Iwamoto I., Douchi T., Kosha S., Murakami M., Fujino T., Nagata Y. Relationships between serum leptin level and regional bone mineral density, bone metabolic markers in healthy women. Acta Obstet. Gynecol. Scand. 79:2000;1060-1064
19. Reseland J.E., Gordeladze J.O. Role of leptin in bone growth: central player or peripheral supporter? FEBS Lett. 528:2002;40-42
20. Steppan C.M., Crawford D.T., Chidsey-Frank K.L., Ke H., Swick A.G. Leptin is a potent stimulator of bone growth in ob/ob mice. Regul. Pept. 92:2000;73-78
21. Liu C., Grossman A., Bain S., Strachan M., Puemer D., Bailey C., et al. Leptin stimulates cortical bone formation in obese (ob/ob) mice. J. Bone Miner. Res. 12(S1):1997;S115
22. Lorentzon R., Alehagen U., Boquist L. Osteopenia in mice with genetic diabetes. Diabetes Res. Clin. Pract. 2:1986;157-163
23. Tamasi J.A., Arey B.J., Bertolini D.R., Feyen J.H.M. Characterization of bone structure in leptin receptor-deficient Zucker (fa/fa) rats. J. Bone Miner. Res. 18:2003;1605-1611