Transfection of p53-knockout mouse fibroblasts with wild-type p53 increases the thermosensitivity and stimulates apoptosis induced by heat stress

International Journal of Radiation Oncology Biology Physics

Volumn 38, Issue 5, 1997, Pages 1089-1095

  Matsumoto, Hideki ^a,b   Takahashi, Akihisa ^a   Wang, Xinjiang ^a   Ohnishi, Ken ^a   Ohnishi, Takeo ^a  

^a NARA MEDICAL UNIVERSITY   (Japan)

^b UNIVERSITY OF FUKUI   (Japan)

Author keywords

Apoptosis; Cell cycle; Hyperthermia; p53; Thermosensitivity

Indexed keywords

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE S PHASE; DNA BINDING; DNA CONTENT; DNA DAMAGE; GENE ACTIVATION; GENETIC TRANSFECTION; GENOTOXICITY; HEAT SENSITIVITY; HEAT STRESS; IONIZING RADIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; ULTRAVIOLET RADIATION;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL CYCLE; CELL SURVIVAL; FIBROBLASTS; G1 PHASE; GENES, P53; GENETIC VECTORS; GENOTYPE; HEAT; HYPERTHERMIA, INDUCED; MICE; MICE, KNOCKOUT; SIGNAL TRANSDUCTION; STRESS; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0030756986     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(97)00300-3     Document Type: Article

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