Apolipoprotein e4 allele is predictor of coronary artery disease death in elderly patients with type 2 diabetes mellitus

Atherosclerosis

Volumn 175, Issue 1, 2004, Pages 77-81

  Guang Da, Xiang ^a   You Ying, Liu ^a   Zhi Song, Chen ^a   Yu Sheng, He ^a   Xiang Jiu, Yang ^b  

^a WUHAN GENERAL HOSPITAL OF GUANGZHOU COMMAND   (China)

^b WUHAN UNIVERSITY   (China)

Author keywords

Apolipoprotein E genotypes; Coronary artery disease; Mortality; Type 2 diabetes mellitus

Indexed keywords

APOLIPOPROTEIN E4; CHOLESTEROL; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ADULT; AGED; ALLELE; ARTICLE; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DEATH; DISCRIMINANT ANALYSIS; DISEASE MARKER; FEMALE; FOLLOW UP; GENOTYPE; HEART FUNCTION; HUMAN; INFORMATION PROCESSING; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MORTALITY; NON INSULIN DEPENDENT DIABETES MELLITUS; POPULATION MODEL; PRIORITY JOURNAL; RISK ASSESSMENT; SPECIES COMPARISON; STATISTICAL ANALYSIS; TIME SERIES ANALYSIS;

AGED; AGED, 80 AND OVER; ALLELES; APOLIPOPROTEIN E4; APOLIPOPROTEINS E; CORONARY DISEASE; DIABETES MELLITUS, TYPE 2; ENDOTHELIUM, VASCULAR; FEMALE; GENOTYPE; HUMANS; LIPIDS; LIPOPROTEINS; MALE; MIDDLE AGED; RISK FACTORS; VASODILATION;

EID: 2942551120     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2004.02.015     Document Type: Article

References (31)

1. Davignon J., Gregg R.E., Sing C.F. Apolipoprotein E polymorphism and atherosclerosis. Atherosclerosis. 8:1988;1-21
2. Luc G., Bard J.M., Arveiler D., et al. Impact of apolipoprotein E polymorphism on lipoproteins and risk of myocardial infarction: The ECTIM Study. Arterioscler. Thromb. 14:1994;1412-1419
3. Tirek L., Menzel H.J., Ehnholm C., Nicaud V., Havekes L.M. ApoE polymorphism and predisposition to coronary heart disease in youth of different European populations: The EARS Study. European Atherosclerosis Research Study. Arterioscler. Thromb. 14:1994;1617-1624
4. Wang X.L., McCredie R.M., Wilcken D.E.L. Polymorphisms of the apolipoprotein E gene and severity of coronary artery disease defined by angiography. Arterioscler Thromb. Vasc. Biol. 15:1995;1030-1034
5. 4 polymorphism increases the risk for exercise-induced silent myocardial ischemia in older men. Arterioscler Thromb. 13:1993;1495-1500
6. Stengård J.H., Pekkanen J., Ehnholm C., Nissinen A., Sing C.F. Genotypes with the apolipoprotein ε4 allele are predictors of coronary heart disease mortality in a longitudinal study of elderly Finnish men. Hum Genet. 97:1996;677-684
7. Laakso M., Kesäniemi Y.A., Kervinen K., Jauhiainen M., Pyörälä K. Relationship of coronary heart disease and apolipoprotein E phenotype in patients with non-insulin-dependent diabetes. Br. Med. J. 303:1991;1159-1162
8. Ukkola O., Kervinen K., Salmela P.I., et al. Apolipoprotein E phenotype is related to macro- and microangiopathy in patients with non-insulin dependent diabetes mellitus. Atherosclerosis. 101:1993;9-15
9. Guangda X., Bangshun X., Xiujian L., Yangzhong H. Apo e4 allele increases the risk for exercise-induced silent myocardial ischemia in non-insulin dependent diabetes mellitus. Atherosclerosis. 149:1999;293-296
10. Guangda X., Yuhua W. Apolipoprotein e4 allele and endothelium-dependent arterial dilation in type 2 diabetes mellitus without angiopathy. Diabetologia. 46:2003;514-519
11. Criteria Committee, New York Heart Association Inc. Diseases of the Heart and Blood Vessels. Nomenclature and criteria for Diagnosis. 6th ed. Boston: Little, Brown and Co.; 1964. p. 114.
12. Bolla M.K., Haddad L., Homphries S.I. High throughput method for determination of apolipoprotein E genotypes with use of restriction digestion analysis by microplate array diagonel gel electrophoresis. Clin. Chem. 41:1995;1600-1606
13. Houlston R.S., Snowden C., Green F., Alberti K.G.M.N., Humphries S.E. Apolipoprotein(apo) E genotypes by polymerase chain reaction and allele specific oligonucleotide probes: no detectable linkage disequilibrium between ApoE and ApoC II. Hum Genet. 83:1989;364-368
14. Avogaro P., Bittolo Bon G., Cazzolato G., Quinci G.B. Are apolipoproteins better discriminators than lipids for atherosclerosis? Lancet. 1:1979;901-903
15. Stamfer M.J., Sacks F.M., Salvini S., Willett W.C., Hennekens C.H. A prospective study of cholesterol lipoproteins and the risk of myocardial infarction. N Engl. J. Med. 325:1991;373-381
16. Wald N.J., Law M., Haddow J.E., Craig W.Y. Apolipoprotiens and prediction of fatal myocardial infarction. Lancet. 359(9320):2002;1864
17. Wald N.J., Law M., Watt H.C., et al. Apolipoproteins and ischaemic heart disease: implications for screening. Lancet. 343(8889):1994;75-79
18. Guangda X., Yangzhong H. Apolipoprotein E genotypes and caroid artery atherosclerosis in diabetes mellitus. Diabetes Res. Clin. Pract. 56(Suppl 1):2002;S149
19. Liu S., Ma J., Ridker P.M., Breslow J.L., Stampfer M.J. A prospective study of the association between APOE genotype and the risk of myocardial infarction among apparently healthy men. Atherosclerosis. 166:2003;323-329
20. Eichner J.E., Kuller L.H., McCallum L.M., Ferrell R.E., Neaton J.D. Relation of apolipoprotein E phenotype to myocardial infarction and mortality from coronary artery disease. Am. J. Cardiol. 71:1993;160-165
21. Guangda X., Bangshun X., Yangzhong H. Distribution of apolipoprotein E genotype in NIDDM patients with vascular complications. CMJ. 111:1998;506
22. Stengård J.H., Zerba K.E., Pekkanen J., et al. Apolipoprotein E polymorphism predicts death from coronary heart disease in a longitudinal study of elderly Finnish men. Circulation. 91:1995;265-269
23. Maher V.M.G., Brown B.G. Lipoprotein (a) and coronary heart disease. Curr Opin. Lipidol. 6:1995;229-235
24. Mijatovic V., vanderMooren M.J., Stehouwer C.D.A., Netelenbos J.C., Kenemans P. Postmenopausal hormone replacement, risk estimation for coronary artery disease and cardiovascular protection. Gynecol. Endocrinol. 13:1999;130-144
25. Skin J.H., Rosenson R.S. Lipoprotein Lp(a) excess and coronary heart disease. Arch. Intern. Med. 157:1997;1170-1176
26. Genest J. Jr., McNamara J.R., Ordovas J.M., et al. Lipoprotein cholesterol apolipoprotein A-I and B and lipoprotein a abnormalities in men with premature coronary artery disease. J. Am. Coll. Cardiol. 19:1992;792-802
27. Bonetti P.O., Lerman L.O., Lerman A. Endothelial dysfunction: a marker of atherosclerotic risk. Arterioscler. Thromb. Vasc. Biol. 33:2003;168-175
28. Gokce N., Keaney J.K. Jr., Hunter L.M., et al. Predictive value of noninvasively determined endothelial dysfunction for long-time cardiovascular events in patients with peripheral vascular disease. J. Am. Coll Cardiol. 41:2003;1769-1775
29. Pepe M.G., Curtiss L.K. Apolipoprotein E is a biologically active constituent of the normal immunoregulatory lipoprotein LDL-In. J. Immunol. 136:1986;3716-3723
30. Mahley K.W. Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science. 240:1988;622-630
31. Ukkola O., Savolainen M.J., Salmela P.I., von Dickhoff K., Kesaniemi Y.A. DNA polymorphisms at the lipoprotein lipase gene are associated with macroangiopathy in type 2 (non-insulin-dependent) diabetes mellitus. Atherosclerosis. 115:1995;99-105