Determination of fexofenadine in human plasma using 96-well solid phase extraction and HPLC with tandem mass spectrometric detection

Journal of Pharmaceutical and Biomedical Analysis

Volumn 35, Issue 4, 2004, Pages 837-846

  Fu, I ^a   Woolf, E J ^a   Matuszewski, B K ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Antihistamine; Fexofenadine; HPLC; Mass spectrometry; P glycoprotein; Plasma

Indexed keywords

ACETONITRILE; AMMONIUM ACETATE; FEXOFENADINE; FORMIC ACID; SORBENT;

ACCURACY; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG DETERMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REACTION TIME; SINGLE DRUG DOSE; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; MASS SPECTROMETRY; TERFENADINE;

EID: 2942546136     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2004.02.016     Document Type: Article

References (11)

1. Fromm M.F. Int. J. Clin. Pharmacol. Ther. 38:1999;69-74
2. Kim R.B., Leake B.F., Choo E.F., Dresser G.K., Kubba S.V., Schwarz U.I., et al. Clin. Pharmacol. Ther. 70:2001;188-199
3. Fromm M.F., Kim R.B., Stein C.M., Wilkinson G.R., Roden D.M. Circulation. 99:1999;552-557
4. Leveque D., Wisniewski S., Jehl F. J. de Pharmacie Clinique. 20:2001;219-223
5. Cvetkovic M., Leake B., Fromm M.F., Wilkinson G.R., Kim R.B. Drug Metab. Dispos. 27:1999;866-871
6. Drescher S., Schaeffeler E., Hitzl M., Hofmann U., Schwab M., Brinkmann U., Eichelbaum M., Fromm M.F. Br. J. Clin. Pharmacol. 53:2002;526-534
7. Simons F.E., Simons K.J. Clin. Pharmacokinet. 36:1999;329-352
8. Simpson K., Jarvis B. Drugs. 59:2000;301-321
9. Coutant J.E., Westmark P.A., Nardella P.A., Walter S.M., Okerholm R.A. J. Chromatogr. 570:1991;139-148
10. Surapaneni S., Khalil S.K.W. J. Liq. Chromatogr. 17:1994;2419-2428
11. Hofmann U., Selier M., Dreacher S., Fromm M.F. J. Chromatogr. B. 766:2002;227-233