The high-resolution X-ray crystallographic structure of the ferritin (EcFtnA) of Escherichia coli; comparison with human H ferritin (HuHF) and the structures of the Fe3+ and Zn2+ derivatives

Journal of Molecular Biology

Volumn 307, Issue 2, 2001, Pages 587-603

  Stillman, T J ^a   Hempstead, P D ^b   Artymiuk, P J ^a   Andrews, S C ^c   Hudson, A J ^a   Treffry, A ^a   Guest, J R ^a   Harrison, P M ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b MASSEY UNIVERSITY   (New Zealand)

^c UNIVERSITY OF READING   (United Kingdom)

Author keywords

Dinuclear sites; EcFtnA; Fe3+ binding; Ferritin; Zn2+ binding

Indexed keywords

AMINO ACID; FERRIC ION; FERRITIN; LIGAND; ZINC DERIVATIVE;

ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; ESCHERICHIA COLI; HYDROPHOBICITY; LIGAND BINDING; METAL BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0035937252     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.4475     Document Type: Article

References (48)

1. Ferritin mutants of Echerichia coli are iron deficient and growth impaired, and fnr mutants are iron deficient
2. Iron storage in bacteria
3. ALSCRIPT a tool to format multiple alignments
4. Iron incorporation into ferritins - Evidence for the transfer of monomeric Fe(III) between ferritin molecules and for the formation of an unusual mineral in the ferritin of Escherichia coli
5. Stages in iron storage in the ferritin of Escherichia coli (EcFtnA): Analysis of Mössbauer spectra reveals a new intermediate
6. Metal binding at the active centre of the ferritin of Escherichia coli. A Mössbauer spectroscopic study
7. Peroxodiferric intermediate of stearoyl-acyl carrier protein Delta(9) desaturase: Oxidase reactivity during single turnover and implications for the mechanism of desaturation
8. Mineralization in ferritin: An efficient means of iron storage
9. The CCP4 suite: Programs for protein crystallography
10. Calculated electrostatic gradients in recombinant human H-chain ferritin
11. An extensively modified version of MOLSCRIPT that includes greatly enhanced colouring capabilities
12. The MIDAS display system
13. Structure of a unique twofold symmetrical heme-binding site
14. X-ray structure of recombinant horse L-chain apoferritin at 2.0 Å resolution: Implications for stability and function
15. Crystal structure of bullfrog M ferritin at 2.8 Å resolution: Analysis of subunit interactions and the binuclear metal center
16. Structure-function relationships in the ferritins
17. Direct observation of the iron-binding sites in a ferritin
18. Comparison of the three-dimensional structures of recombinant human H and horse L ferritins at high resolution
19. Overproduction, purification and characterisation of the Escherichia coli ferritin
20. A short Fe-Fe distance in peroxodiferric ferritin: Control of Fe substrate versus cofactor decay?
21. Cloning and sequencing of an Escherichia coli K12 gene which encodes a polypeptide having similarity to the human ferritin H-subunit
22. Loop mutations can cause a substantial conformational change in the carboxy terminus of the ferritin protein
23. Interactive computer graphics: FRODO
24. Dictionary of protein secondary structure-pattern-recognition of hydrogen-bonded and geometrical features
25. MOLSCRIPT: A progam to produce both detailed and schematic plots of protein structures
26. PROCHECK: A program to check the stereochemical quality of protein structures
27. Solving the structure of human H-ferritin by genetically engineering intermolecular crystal contacts
28. Recent changes to the MOSFLM package for processing film and image plate data
29. Evidence that residues exposed on the three-fold channels have active roles in the mechanism of ferritin iron incorporation
30. Crystal structures of reduced protein R2 of ribonucleotide reductase: The structural basis for oxygen activation at a dinuclear iron site
31. 2-activation by non-heme diiron proteins: Identification of a symmetric μ-1,2-peroxide in a mutant of ribonucleotide reductase
32. 2-activating non-heme diiron proteins
33. Di-iron-carboxylate proteins
34. Processing of X-ray diffraction data collected in oscillation mode
35. 3+ multimers, including a trimer, during H-type subunit ferritin mineralization
36. Direct spectroscopic and kinetic evidence for the involvement of a peroxodiiron intermediate during the ferroxidase reaction in fast ferritin mineralization
37. Geometry of the soluble methane monooxygenase catalytic diiron center in two oxidation states
38. Evidence that the specificity of iron incorporation into homopolymers of human ferritin L- and H- chains is conferred by the nucleation and ferroxidase centers
39. RASMOL-Biomolecular graphics for all
40. Mechanism of catalysis of Fe(II) oxidation by ferritin H-chains
41. Iron(II) oxidation by the H-chain ferritin and evidence from site-directed mutagenesis that a transient blue species is formed at the dinuclear iron center
42. Dinuclear center of ferritin: Studies of iron binding and oxidation show differences in the two iron sites
43. How the presence of three iron binding sites affects the iron storage function of the ferritin (EcFtnA) of Escherichia coli
44. The use of zinc(II) to probe iron binding and oxidation by the ferritin (EcFtnA) of Escherichia coli
45. High-resolution crystal-structures of amphibian red-cell L-ferritin - Potential roles for structural plasticity and solvation in function
46. An efficient general purpose least squares refinement program for macromolecular structures
47. Reaction paths of iron oxidation and hydrolysis in horse spleen and recombinant human ferritins
48. Catalytic iron (II) oxidation in the non-haem ferritin of Escherichia coli: The early intermediate is not an iron tyrosinate