A high-throughput model for screening anti-tumor agents capable of promoting polymerization of tubulin in vitro

Acta Pharmacologica Sinica

Volumn 25, Issue 6, 2004, Pages 775-782

  Hu, Wei ^a   Dong, Hui ^a   Li, Yue Zhong ^a   Hu, Xi Tao ^a   Han, Guan Jun ^a   Qu, Yin Bo ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Antitumor drug screening assays; Microtubules; Tubulin polymerization promotor

Indexed keywords

ANTINEOPLASTIC AGENT; CYTOTOXIC AGENT; EPOTHILONE A; EPOTHILONE DERIVATIVE; GUANOSINE TRIPHOSPHATE; NATURAL PRODUCT; TUBULIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; HELA CELL; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IC 50; KINETICS; MICROTUBULE; MODEL; NITROBLUE TETRAZOLIUM TEST; PHARMACOPHORE; PROTEIN POLYMERIZATION; PROTEIN PURIFICATION;

ANTINEOPLASTIC AGENTS; DRUG EVALUATION, PRECLINICAL; DRUG SCREENING ASSAYS, ANTITUMOR; EPOTHILONES; HELA CELLS; HUMANS; INHIBITORY CONCENTRATION 50; MICROTUBULES; PACLITAXEL; TUBULIN;

EID: 2942538660     PISSN: 16714083     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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