메뉴 건너뛰기




Volumn 68, Issue 1, 2004, Pages 11-21

An in vitro model system that can differentiate the stages of DNA replication affected by anticancer agents

Author keywords

1 D arabinofuranosylcytosine triphosphate; 1 D arabinofuranosylcytosine; ara C; ara CTP; camptothecin; CPT; DNA replication; DNA synthesome; DOX; Doxorubicin; ori; origin of DNA replication; simian virus 40; SV40; SV40 large T antigen; T Ag

Indexed keywords

1BETA DEXTRO ARABINOFURANOSYLCYTOSINE; ANTINEOPLASTIC AGENT; CAMPTOTHECIN; DOXORUBICIN; UNCLASSIFIED DRUG;

EID: 2942536317     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2004.03.021     Document Type: Article
Times cited : (8)

References (54)
  • 1
    • 0029850608 scopus 로고    scopus 로고
    • The human cell multiprotein DNA replication complex (MRC): The effect of camptothecin on its ability to support in vitro DNA synthesis
    • Coll J.M., Hickey R.J., Wei Y., Malkas L.H. The human cell multiprotein DNA replication complex (MRC): the effect of camptothecin on its ability to support in vitro DNA synthesis. Cancer Chemother. Pharmacol. 39:1996;97-102
    • (1996) Cancer Chemother. Pharmacol. , vol.39 , pp. 97-102
    • Coll, J.M.1    Hickey, R.J.2    Wei, Y.3    Malkas, L.H.4
  • 3
    • 1442272641 scopus 로고    scopus 로고
    • Ara-C affects formation of cancer cell DNA synthesome replication intermediates
    • Abdel-Aziz W., Jiang H., Hickey R.J., Malkas L.H. Ara-C affects formation of cancer cell DNA synthesome replication intermediates. Cancer Chemother. Parmacol. 45:2000;312-319
    • (2000) Cancer Chemother. Parmacol. , vol.45 , pp. 312-319
    • Abdel-Aziz, W.1    Jiang, H.2    Hickey, R.J.3    Malkas, L.H.4
  • 4
    • 0034061749 scopus 로고    scopus 로고
    • Effects of gemcitabine and araC on in vitro DNA synthesis mediated by the human breast cell DNA synthesome
    • Jiang H.Y., Hickey R.J., Abdel-Aziz W., Malkas L.H. Effects of gemcitabine and araC on in vitro DNA synthesis mediated by the human breast cell DNA synthesome. Cancer Chemother. Pharmacol. 45:2000;320-328
    • (2000) Cancer Chemother. Pharmacol. , vol.45 , pp. 320-328
    • Jiang, H.Y.1    Hickey, R.J.2    Abdel-Aziz, W.3    Malkas, L.H.4
  • 5
    • 0034257228 scopus 로고    scopus 로고
    • Differential inhibition of the human cell DNA replication complex-associated DNA polymerases by the antimetabolite 1-β-D- arabinofuranosylcytosine triphosphate (ara-CTP)
    • Han S., Hickey R.J., Tom T.D., Wills P.W., Syväoja J.E., Malkas L.H. Differential inhibition of the human cell DNA replication complex-associated DNA polymerases by the antimetabolite 1-β-D-arabinofuranosylcytosine triphosphate (ara-CTP). Biochem. Pharmacol. 60:2000;403-411
    • (2000) Biochem. Pharmacol. , vol.60 , pp. 403-411
    • Han, S.1    Hickey, R.J.2    Tom, T.D.3    Wills, P.W.4    Syväoja, J.E.5    Malkas, L.H.6
  • 6
    • 0033803021 scopus 로고    scopus 로고
    • Ara-C differentially affects multiprotein forms of human cell DNA polymerase
    • Wills P.W., Hickey R., Malkas L. Ara-C differentially affects multiprotein forms of human cell DNA polymerase. Cancer Chemother. Pharmacol. 46:2000;193-203
    • (2000) Cancer Chemother. Pharmacol. , vol.46 , pp. 193-203
    • Wills, P.W.1    Hickey, R.2    Malkas, L.3
  • 7
    • 0025346309 scopus 로고
    • A 21S enzyme complex from HeLa cells that functions in simian virus 40 DNA replication in vitro
    • Malkas L.H., Hickey R.J., Li C., Pederson N., Baril E.F. A 21S enzyme complex from HeLa cells that functions in simian virus 40 DNA replication in vitro. Biochemistry. 29:1990;6362-6374
    • (1990) Biochemistry , vol.29 , pp. 6362-6374
    • Malkas, L.H.1    Hickey, R.J.2    Li, C.3    Pederson, N.4    Baril, E.F.5
  • 9
    • 0030426391 scopus 로고    scopus 로고
    • The human breast cell DNA synthesome: Its purification from tumor tissue and cell culture
    • Coll J.M., Sekowski J.W., Hickey R.J., Schnaper L., Yue W., Brodie A.M.H., et al. The human breast cell DNA synthesome: its purification from tumor tissue and cell culture. Oncol. Res. 8:1996;435-447
    • (1996) Oncol. Res. , vol.8 , pp. 435-447
    • Coll, J.M.1    Sekowski, J.W.2    Hickey, R.J.3    Schnaper, L.4    Yue, W.5    Brodie, A.M.H.6
  • 10
    • 0029808055 scopus 로고    scopus 로고
    • The expression of poly(ADP-ribose) polymerase during differentiation- linked DNA replication reveals that it is a component of the multiprotein DNA replication complex
    • Simbulan-Rosenthal C.M., Rosenthal D.C., Hilz H., Hickey R., Malkas L., Applegren N., et al. The expression of poly(ADP-ribose) polymerase during differentiation-linked DNA replication reveals that it is a component of the multiprotein DNA replication complex. Biochemistry. 35:1996;11622-11633
    • (1996) Biochemistry , vol.35 , pp. 11622-11633
    • Simbulan-Rosenthal, C.M.1    Rosenthal, D.C.2    Hilz, H.3    Hickey, R.4    Malkas, L.5    Applegren, N.6
  • 11
    • 0032581005 scopus 로고    scopus 로고
    • Regulation of the expression or recruitment of components of the DNA synthesome by poly(ADP-ribose) polymerase
    • Simbulan-Rosenthal C.M., Rosenthal D.S., Boulares A.H., Hickey R.J., Malkas L.H., Coll J.M., et al. Regulation of the expression or recruitment of components of the DNA synthesome by poly(ADP-ribose) polymerase. Biochemistry. 37:1998;9363-9370
    • (1998) Biochemistry , vol.37 , pp. 9363-9370
    • Simbulan-Rosenthal, C.M.1    Rosenthal, D.S.2    Boulares, A.H.3    Hickey, R.J.4    Malkas, L.H.5    Coll, J.M.6
  • 12
    • 0030929389 scopus 로고    scopus 로고
    • The isolation of a DNA synthesome from human leukemia cells
    • Lin S., Hickey R.J., Malkas L.H. The isolation of a DNA synthesome from human leukemia cells. Leuk. Res. 21:1997;501-512
    • (1997) Leuk. Res. , vol.21 , pp. 501-512
    • Lin, S.1    Hickey, R.J.2    Malkas, L.H.3
  • 15
    • 0029805303 scopus 로고    scopus 로고
    • Identification of multiprotein complexes containing DNA replication factors by native immunoblotting of HeLa cell protein preparations with T-antigen dependent SV40 DNA replication activity
    • Tom T.D., Hickey R.J., Malkas L.H. Identification of multiprotein complexes containing DNA replication factors by native immunoblotting of HeLa cell protein preparations with T-antigen dependent SV40 DNA replication activity. J. Cell. Biochem. 63:1996;259-267
    • (1996) J. Cell. Biochem. , vol.63 , pp. 259-267
    • Tom, T.D.1    Hickey, R.J.2    Malkas, L.H.3
  • 16
    • 0003002288 scopus 로고
    • Replication of SV40 and polyoma virus chromosomes
    • Salzman PN, editor. New York: Plenum Press
    • DePamphilis ML, Bradley MK. Replication of SV40 and polyoma virus chromosomes. In: Salzman PN, editor. The papovaviridae: the polyomavirus. New York: Plenum Press; 1986. p. 99-246.
    • (1986) The Papovaviridae: The Polyomavirus , pp. 99-246
    • DePamphilis, M.L.1    Bradley, M.K.2
  • 17
    • 0021970530 scopus 로고
    • An immunoaffinity purification procedure for SV40 large T-antigen
    • Simanis V., Lane D.P. An immunoaffinity purification procedure for SV40 large T-antigen. Virology. 144:1985;88-100
    • (1985) Virology , vol.144 , pp. 88-100
    • Simanis, V.1    Lane, D.P.2
  • 19
    • 0025824979 scopus 로고
    • Mechanism of inhibition of cell proliferation by vinca alkaloids
    • Jordan M.A., Thrower D., Wilson L. Mechanism of inhibition of cell proliferation by vinca alkaloids. Cancer Res. 51:1991;2212-2222
    • (1991) Cancer Res. , vol.51 , pp. 2212-2222
    • Jordan, M.A.1    Thrower, D.2    Wilson, L.3
  • 20
    • 0342564930 scopus 로고
    • Initiation of simian virus 40 DNA replication in vitro: Large-tumor-antigen- and origin-dependent unwinding of the template
    • Wold M.S., Li J.J., Kelly T.J. Initiation of simian virus 40 DNA replication in vitro: large-tumor-antigen- and origin-dependent unwinding of the template. Proc. Natl. Acad. Sci. U.S.A. 84:1987;3643-3647
    • (1987) Proc. Natl. Acad. Sci. U.S.A. , vol.84 , pp. 3643-3647
    • Wold, M.S.1    Li, J.J.2    Kelly, T.J.3
  • 21
    • 0021830055 scopus 로고
    • Replication and supercoiling of simian virus 40 DNA in cell extracts from human cells
    • Stillman B.W., Gluzman Y. Replication and supercoiling of simian virus 40 DNA in cell extracts from human cells. Mol. Cell. Biol. 5:1985;2051-2060
    • (1985) Mol. Cell. Biol. , vol.5 , pp. 2051-2060
    • Stillman, B.W.1    Gluzman, Y.2
  • 22
    • 0017343592 scopus 로고
    • Effect of cytosine arabinoside on replicon initiation in human lymphoblasts
    • Fridland A. Effect of cytosine arabinoside on replicon initiation in human lymphoblasts. Biochem. Biophys. Res. Commun. 74:1977;72-78
    • (1977) Biochem. Biophys. Res. Commun. , vol.74 , pp. 72-78
    • Fridland, A.1
  • 23
    • 0017625121 scopus 로고
    • Inhibition of deoxyribonucleic acid chain initiation: A new mode of action for 1-β-D-arabinofuranosylcytosine in human lymphoblasts
    • Fridland A. Inhibition of deoxyribonucleic acid chain initiation: a new mode of action for 1-β-D-arabinofuranosylcytosine in human lymphoblasts. Biochemistry. 16:1977;5308-5312
    • (1977) Biochemistry , vol.16 , pp. 5308-5312
    • Fridland, A.1
  • 24
    • 0023677076 scopus 로고    scopus 로고
    • Functional consequences of the arabinosylcytosine structural lesions in DNA
    • Mikita T., Beardsley P. Functional consequences of the arabinosylcytosine structural lesions in DNA. Biochemistry. 27:1998;4698-4705
    • (1998) Biochemistry , vol.27 , pp. 4698-4705
    • Mikita, T.1    Beardsley, P.2
  • 25
    • 0026468410 scopus 로고
    • Incorporation of cytosine arabinoside monophosphate into DNA at internucleotide linkages by human DNA polymerase α
    • Perrino F.W., Mekosh H.L. Incorporation of cytosine arabinoside monophosphate into DNA at internucleotide linkages by human DNA polymerase α J. Biol. Chem. 267:1992;23043-23051
    • (1992) J. Biol. Chem. , vol.267 , pp. 23043-23051
    • Perrino, F.W.1    Mekosh, H.L.2
  • 26
    • 0031972535 scopus 로고    scopus 로고
    • Ara-C: Cellular and molecular pharmacology
    • Grant S. Ara-C: cellular and molecular pharmacology. Adv. Cancer Res. 72:1998;197-233
    • (1998) Adv. Cancer Res. , vol.72 , pp. 197-233
    • Grant, S.1
  • 27
    • 0027417363 scopus 로고
    • Cellular pharmacodynamics of anticancer drugs
    • Plunkett W., Gandhi V. Cellular pharmacodynamics of anticancer drugs. Semin. Oncol. 20:1993;50-63
    • (1993) Semin. Oncol. , vol.20 , pp. 50-63
    • Plunkett, W.1    Gandhi, V.2
  • 28
    • 0023924786 scopus 로고
    • Identification of mammalian DNA-topoisomerase I as an intracellular target of the anticancer drug camptothecin
    • Hsiang Y.H., Liu L.F. Identification of mammalian DNA-topoisomerase I as an intracellular target of the anticancer drug camptothecin. Cancer Res. 48:1988;1722-1726
    • (1988) Cancer Res. , vol.48 , pp. 1722-1726
    • Hsiang, Y.H.1    Liu, L.F.2
  • 29
    • 0024324205 scopus 로고
    • On the mechanism of topoisomerase I inhibition by camptothecin: Evidence for binding to an enzyme-DNA complex
    • Hertzberg R.P., Caranfa M.J., Hecht S.M. On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex. Biochemistry. 28:1989;4629-4638
    • (1989) Biochemistry , vol.28 , pp. 4629-4638
    • Hertzberg, R.P.1    Caranfa, M.J.2    Hecht, S.M.3
  • 30
    • 0029960812 scopus 로고    scopus 로고
    • Eukaryotic DNA-topoisomerase I: Genome gatekeeper and its intruders, camptothecins
    • Pommier Y. Eukaryotic DNA-topoisomerase I: genome gatekeeper and its intruders, camptothecins. Semin. Oncol. 23(Suppl 3):1996;3-10
    • (1996) Semin. Oncol. , vol.23 , Issue.SUPPL. 3 , pp. 3-10
    • Pommier, Y.1
  • 31
    • 0029944106 scopus 로고    scopus 로고
    • Antitopoisomerase drug action and resistance
    • Nitiss J.L., Beck W.T. Antitopoisomerase drug action and resistance. Eur. J. Cancer. 32A:1996;958-966
    • (1996) Eur. J. Cancer , vol.32 , pp. 958-966
    • Nitiss, J.L.1    Beck, W.T.2
  • 32
    • 0028174984 scopus 로고
    • DNA-topoisomerases: Essential enzymes and lethal targets
    • Chen A.Y., Liu L.F. DNA-topoisomerases: essential enzymes and lethal targets. Annu. Rev. Pharmacol. Toxicol. 34:1994;191-218
    • (1994) Annu. Rev. Pharmacol. Toxicol. , vol.34 , pp. 191-218
    • Chen, A.Y.1    Liu, L.F.2
  • 34
    • 0029144134 scopus 로고
    • Topoisomerase poisons: Harnessing the dark side of enzyme mechanism
    • Froelich-Ammon S.J., Osheroff N. Topoisomerase poisons: harnessing the dark side of enzyme mechanism. J. Biol. Chem. 270:1995;21429-21432
    • (1995) J. Biol. Chem. , vol.270 , pp. 21429-21432
    • Froelich-Ammon, S.J.1    Osheroff, N.2
  • 36
    • 0014945052 scopus 로고
    • DNA replication in SV40 infected cells. I. Analysis of replicating SV40 DNA
    • Levine A.J., Kang H.Y., Billheimer E.F. DNA replication in SV40 infected cells. I. Analysis of replicating SV40 DNA. J. Mol. Biol. 50:1970;549-564
    • (1970) J. Mol. Biol. , vol.50 , pp. 549-564
    • Levine, A.J.1    Kang, H.Y.2    Billheimer, E.F.3
  • 37
    • 0027551247 scopus 로고
    • SV40 DNA replication intermediates: Analysis of drugs which target mammalian DNA replication
    • Snapka R.M., Permana P.A. SV40 DNA replication intermediates: analysis of drugs which target mammalian DNA replication. BioEssays. 15:1993;121-127
    • (1993) BioEssays , vol.15 , pp. 121-127
    • Snapka, R.M.1    Permana, P.A.2
  • 39
  • 40
    • 0010227867 scopus 로고
    • In vitro replication of duplex circular DNA containing the simian virus 40 DNA origin site
    • Wobbe C.R., Dean F., Weissbach L., Hurwitz J. In vitro replication of duplex circular DNA containing the simian virus 40 DNA origin site. Proc. Natl. Acad. Sci. U.S.A. 82:1985;5710-5714
    • (1985) Proc. Natl. Acad. Sci. U.S.A. , vol.82 , pp. 5710-5714
    • Wobbe, C.R.1    Dean, F.2    Weissbach, L.3    Hurwitz, J.4
  • 41
    • 0024420685 scopus 로고
    • Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin
    • Hsiang Y.-H., Lihou M.G., Liu L.F. Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin. Cancer Res. 49:1989;5077-5082
    • (1989) Cancer Res. , vol.49 , pp. 5077-5082
    • Hsiang, Y.-H.1    Lihou, M.G.2    Liu, L.F.3
  • 42
    • 0027139317 scopus 로고
    • Interaction between replication forks and topoisomerase I-DNA cleavage complexes: Studies in a cell-free SV40 DNA replication system
    • Tsao Y.-P., Russo A., Nyamuswa G., Silber R., Liu L.F. Interaction between replication forks and topoisomerase I-DNA cleavage complexes: studies in a cell-free SV40 DNA replication system. Cancer Res. 53:1993;5908-5914
    • (1993) Cancer Res. , vol.53 , pp. 5908-5914
    • Tsao, Y.-P.1    Russo, A.2    Nyamuswa, G.3    Silber, R.4    Liu, L.F.5
  • 43
    • 0026776087 scopus 로고
    • Effect of ICRF-193, a novel DNA-topoisomerase II inhibitor, on simian virus 40 DNA and chromosome replication in vitro
    • Ishimi Y., Ishida R., Andoh T. Effect of ICRF-193, a novel DNA-topoisomerase II inhibitor, on simian virus 40 DNA and chromosome replication in vitro. Mol. Cell. Biol. 12:1992;4007-4014
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 4007-4014
    • Ishimi, Y.1    Ishida, R.2    Andoh, T.3
  • 44
    • 0026544211 scopus 로고
    • Topoisomerase II plays an essential role as a swivelase in the late stage of SV40 chromosome replication in vitro
    • Ishimi Y., Sugasawa K., Hanaoka F., Eki T., Hurwitz J. Topoisomerase II plays an essential role as a swivelase in the late stage of SV40 chromosome replication in vitro. J. Biol. Chem. 267:1992;462-466
    • (1992) J. Biol. Chem. , vol.267 , pp. 462-466
    • Ishimi, Y.1    Sugasawa, K.2    Hanaoka, F.3    Eki, T.4    Hurwitz, J.5
  • 45
    • 0023002286 scopus 로고
    • Topoisomerase inhibitors can selectively interfere with different stages of simian virus 40 DNA replication
    • Snapka R.M. Topoisomerase inhibitors can selectively interfere with different stages of simian virus 40 DNA replication. Mol. Cell. Biol. 6:1986;4221-4227
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 4221-4227
    • Snapka, R.M.1
  • 46
    • 0019417775 scopus 로고
    • Arrest of segregation leads to accumulation of highly interwined catenated dimers: Dissection of the final stages of SV40 DNA replication
    • Sundin O., Varshavsky A. Arrest of segregation leads to accumulation of highly interwined catenated dimers: dissection of the final stages of SV40 DNA replication. Cell. 25:1981;659-669
    • (1981) Cell , vol.25 , pp. 659-669
    • Sundin, O.1    Varshavsky, A.2
  • 47
    • 0023187273 scopus 로고
    • Effects of VM26 (teniposide), a specific inhibitor of type II DNA-topoisomerase, on SV40 DNA replication in vivo
    • Richter A., Strausfeld U., Knippers R. Effects of VM26 (teniposide), a specific inhibitor of type II DNA-topoisomerase, on SV40 DNA replication in vivo. Nucl. Acids Res. 15:1987;3455-3468
    • (1987) Nucl. Acids Res. , vol.15 , pp. 3455-3468
    • Richter, A.1    Strausfeld, U.2    Knippers, R.3
  • 48
    • 0023685075 scopus 로고
    • Effects of VM26, a specific inhibitor of type II DNA-topoisomerase, on SV40 chromatin replication in vitro
    • Richter A., Strausfeld U. Effects of VM26, a specific inhibitor of type II DNA-topoisomerase, on SV40 chromatin replication in vitro. Nucl. Acids Res. 16:1988;10119-10129
    • (1988) Nucl. Acids Res. , vol.16 , pp. 10119-10129
    • Richter, A.1    Strausfeld, U.2
  • 49
    • 0023958614 scopus 로고
    • Swiveling and decatenation of replicating simian virus 40 genomes in vivo
    • Snapka R.M., Powelson M.A., Strayer J.M. Swiveling and decatenation of replicating simian virus 40 genomes in vivo. Mol. Cell Biol. 8:1988;515-521
    • (1988) Mol. Cell Biol. , vol.8 , pp. 515-521
    • Snapka, R.M.1    Powelson, M.A.2    Strayer, J.M.3
  • 50
    • 0035400747 scopus 로고    scopus 로고
    • Imbalanced DNA synthesis induced by cytosine arabinoside and fludarabine in human leukemia cells
    • Carbone G.M.R., Catapano C.V., Fernandes D.J. Imbalanced DNA synthesis induced by cytosine arabinoside and fludarabine in human leukemia cells. Biochem. Pharmacol. 62:2001;101-110
    • (2001) Biochem. Pharmacol. , vol.62 , pp. 101-110
    • Carbone, G.M.R.1    Catapano, C.V.2    Fernandes, D.J.3
  • 51
    • 0018868388 scopus 로고
    • Mode of action of 9-β-D-arabinosyladenine and 1-β-D- arabinosylcytosine on DNA synthesis in human lymphoblasts
    • Bell D.E., Fridland A. Mode of action of 9-β-D-arabinosyladenine and 1-β-D-arabinosylcytosine on DNA synthesis in human lymphoblasts. Biochim. Biophys. Acta. 606:1980;57-66
    • (1980) Biochim. Biophys. Acta , vol.606 , pp. 57-66
    • Bell, D.E.1    Fridland, A.2
  • 52
    • 0032567349 scopus 로고    scopus 로고
    • Involvement of topoisomerases in the initiation of simian virus 40 minichromosome replication
    • Halmer L., Vestner B., Gruss C. Involvement of topoisomerases in the initiation of simian virus 40 minichromosome replication. J. Biol. Chem. 273:1998;34792-34798
    • (1998) J. Biol. Chem. , vol.273 , pp. 34792-34798
    • Halmer, L.1    Vestner, B.2    Gruss, C.3
  • 54
    • 0034124053 scopus 로고    scopus 로고
    • Conversion of topoisomerase I cleavage complexes on the leading strand of ribosomal DNA into 5′-phosphorylated DNA double-strand breaks by replication runoff
    • Strumberg D., Pilon A.A., Smith M., Hickey R., Malkas L., Pommier Y. Conversion of topoisomerase I cleavage complexes on the leading strand of ribosomal DNA into 5′-phosphorylated DNA double-strand breaks by replication runoff. Mol. Cell. Biol. 20:2000;3977-3987
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 3977-3987
    • Strumberg, D.1    Pilon, A.A.2    Smith, M.3    Hickey, R.4    Malkas, L.5    Pommier, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.