Up-regulation of lymphocytic cholinergic activity by ONO-4819, a selective prostaglandin EP4 receptor agonist, in MOLT-3 human leukemic T cells

Vascular Pharmacology

Volumn 41, Issue 2, 2004, Pages 51-58

  Suenaga, Aya ^a   Fujii, Takeshi ^a   Ogawa, Hiroshi ^a   Maruyama, Takayuki ^b   Ohuchida, Shuichi ^b   Katsube, Nobuo ^b   Obata, Takaaki ^b   Kawashima, Koichiro ^a  

^a KEIO UNIVERSITY   (Japan)

^b ONO PHARMACEUTICAL CO   (Japan)

Author keywords

Acetylcholine; Choline acetyltransferase; ONO 4819, PGE 2; T lymphocyte

Indexed keywords

7 [3 HYDROXY 2 [3 HYDROXY 4 (3 METHOXYMETHYLPHENYL) 1 BUTENYL] 5 OXOCYCLOPENTYL] 5 THIAHEPTANOIC ACID METHYL ESTER; ACETYLCHOLINE; CHOLINE ACETYLTRANSFERASE; MESSENGER RNA; PHYTOHEMAGGLUTININ; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN EP 4 RECEPTOR AGONIST; PROSTAGLANDIN EP1 RECEPTOR; PROSTAGLANDIN EP2 RECEPTOR; PROSTAGLANDIN EP3 RECEPTOR; PROSTAGLANDIN EP4 RECEPTOR; PROSTAGLANDIN RECEPTOR STIMULATING AGENT; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ACETYLCHOLINE RELEASE; ARTICLE; CELL CULTURE; CELL LEVEL; CELL PROLIFERATION; CELL STIMULATION; CHOLINERGIC ACTIVITY; CHOLINERGIC TRANSMISSION; CONTROLLED STUDY; DRUG EXPOSURE; DRUG SELECTIVITY; ENZYME ACTIVITY; GENE EXPRESSION; HUMAN; HUMAN CELL; INHIBITION KINETICS; LEUKEMIA CELL LINE; LYMPHOCYTE; LYMPHOCYTE ACTIVATION; PRIORITY JOURNAL; REGULATORY MECHANISM; T LYMPHOCYTE; TIME; UPREGULATION;

ACETYLCHOLINE; CELL LINE, TUMOR; CHOLINE O-ACETYLTRANSFERASE; HEPTANOATES; HUMANS; LEUKEMIA, T-CELL; RECEPTORS, PROSTAGLANDIN E; RNA, MESSENGER; T-LYMPHOCYTES; UP-REGULATION;

EID: 2942513060     PISSN: 15371891     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vph.2004.03.006     Document Type: Article

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