Synthesis, spectroscopy (IR, multinuclear NMR, ESI-MS), diffraction, density functional study and in vitro antiproliferative activity of pyrazole-beta-diketone dihalotin(IV) compounds on 5 melanoma cell lines

Journal of Inorganic Biochemistry

Volumn 100, Issue 1, 2006, Pages 58-69

  Pettinari, Claudio ^a   Caruso, Francesco ^b   Zaffaroni, Nadia ^c   Villa, Raffaella ^c   Marchetti, Fabio ^a   Pettinari, Riccardo ^a   Phillips, Christine ^d   Tanski, Joseph ^d   Rossi, Miriam ^d  

^a UNIVERSITY OF CAMERINO   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c NATIONAL CANCER INSTITUTE   (Italy)

^d VASSAR COLLEGE   (United States)

Author keywords

Diketone; Crystal; Melanoma; NMR; Tin

Indexed keywords

BIS(4 ACETYL 1,2 DIHYDRO 1,3 DIMETHYLPYRAZOL 5 ONE)DICHLOROTIN; BIS[1,2 DIHYDRO 3 METHYL 1 PHENYL 4 (2 PHENYLACETYL)PYRAZOL 5 ONATO]DIBROMOTIN; BIS[1,2 DIHYDRO 3 METHYL 1 PHENYL 4 (2 PHENYLACETYL)PYRAZOL 5 ONATO]DICHLOROTIN; BIS[1,2 DIHYDRO 3 METHYL 1 PHENYL 4 (2 PHENYLACETYL)PYRAZOL 5 ONATO]DIIODOTIN; BIS[1,2 DIHYDRO 3 METHYL 1 PHENYL 4 (2,2 DIPHENYLACETYL)PYRAZOL 5 ONATO]DIBROMOTIN; BIS[1,2 DIHYDRO 3 METHYL 1 PHENYL 4 (2,2 DIPHENYLACETYL)PYRAZOL 5 ONATO]DICHLOROTIN; BIS[1,2 DIHYDRO 3 METHYL 1 PHENYL 4 (2,2 DIPHENYLACETYL)PYRAZOL 5 ONATO]DIFLUOROTIN; BIS[1,2 DIHYDRO 3 METHYL 1 PHENYL 4 (2,2 DIPHENYLACETYL)PYRAZOL 5 ONATO]DIIODOTIN; BIS[4 (2,2,2 TRIFLUOROACETYL) 1,2 DIHYDRO 3 METHYL 1 (PYRIDIN 2 YL)PYRAZOL 5 ONATO]DIBROMOTIN; BIS[4 (2,2,2 TRIFLUOROACETYL) 1,2 DIHYDRO 3 METHYL 1 (PYRIDIN 2 YL)PYRAZOL 5 ONATO]DICHLOROTIN; HALIDE; PYRAZOLE DERIVATIVE; PYRIDINE DERIVATIVE; TIN; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL CLONE; CELL PROLIFERATION; CHEMICAL BOND; CONTROLLED STUDY; CORRELATION ANALYSIS; DENSITY FUNCTIONAL THEORY; DIFFRACTION; DRUG SYNTHESIS; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; HUMAN CELL; IN VITRO SELECTION; IN VITRO STUDY; INFRARED SPECTROSCOPY; ISOMER; MELANOMA CELL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTON NUCLEAR MAGNETIC RESONANCE; SOLID; SPECTROSCOPY; STRUCTURE ANALYSIS; X RAY;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MELANOMA; ORGANOMETALLIC COMPOUNDS; PYRAZOLES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, INFRARED; TIN COMPOUNDS; X-RAY DIFFRACTION;

EID: 29344463046     PISSN: 01620134     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jinorgbio.2005.10.002     Document Type: Article

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