Characterization of kinetics and products of the Baeyer-Villiger oxygenase MtmOIV, the key enzyme of the biosynthetic pathway toward the natural product anticancer drug mithramycin from Streptomyces argillaceus

Journal of the American Chemical Society

Volumn 127, Issue 50, 2005, Pages 17594-17595

  Gibson, Miranda ^a   Nur E Alam, Mohammad ^a   Lipata, Fredilyn ^a   Oliveira, Marcos A ^a   Rohr, Jürgen ^a  

^a University of Kentucky   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; MITHRAMYCIN; MITHRAMYCIN DK; MITHRAMYCIN SA; MITHRAMYCIN SDK; MITHRAMYCIN SK; NATURAL PRODUCT; OXYGENASE; UNCLASSIFIED DRUG;

ALDOL REACTION; ARTICLE; BAEYER VILLIGER REACTION; CATALYSIS; CHEMICAL REACTION KINETICS; DRUG SYNTHESIS; ENZYME ANALYSIS; GLYCOSYLATION; MOLECULAR INTERACTION; OXIDATION; PH; STREPTOMYCES ARGILLACEUS; STREPTOMYCETACEAE;

ESCHERICHIA COLI; FLAVIN-ADENINE DINUCLEOTIDE; KINETICS; NADP; OXIDATION-REDUCTION; OXYGENASES; PLICAMYCIN; STREPTOMYCES;

EID: 29344449110     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja055750t     Document Type: Article

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