Comparison of efficacy of oral valacyclovir and topical acyclovir in the treatment of herpes simplex keratitis: A randomized clinical trial

Chemotherapy

Volumn 52, Issue 1, 2005, Pages 29-31

  Sozen, Engin ^a   Avunduk, Avni Murat ^a   Akyol, Nurettin ^a  

^a KARADENIZ TECHNICAL UNIVERSITY   (Turkey)

Author keywords

Cornea; Herpes simplex keratitis; Oral valacyclovir; Topical acyclovir; Treatment

Indexed keywords

ACICLOVIR; VALACICLOVIR;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL EXAMINATION; CLINICAL FEATURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HERPES SIMPLEX KERATITIS; HERPES VIRUS; HUMAN; MALE; PHOTOPHOBIA; PRESCRIPTION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SLIT LAMP;

ACYCLOVIR; ADMINISTRATION, ORAL; ADMINISTRATION, TOPICAL; FEMALE; HUMANS; KERATITIS, HERPETIC; MALE; VALINE;

EID: 29344438405     PISSN: 00093157     EISSN: None     Source Type: Journal    
DOI: 10.1159/000090239     Document Type: Article

References (5)

1. Collum LMT, McGettrick, Akhtar J, Lavin J, Rees PJ: Oral acyclovir in herpes simplex dendritic corneal ulceration. Br J Ophthalmol 1986;70:435-438.
2. Perry CM, Faulds D: Valaciclovir. A review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in herpesvirus infections. Drugs 1996;52:754-772.
3. Collum LMT, Akhtar J, McGettrick P: Oral acyclovir in herpetic keratitis. Trans Ophthalmol Soc UK 1985;104:629-632.
4. Porter SM, Patterson A, Kho P: A comparison of local and systemic acyclovir in the management of herpetic disciform keratitis. Br J Ophthalmol 1990;74:283-285.
5. Edert DY, Finance CM, Faou AE: Susceptibility of clinical strains of herpes simplex virus to three nucleoside analogues. Chemotherapy 2000;46:195-197.