The effect of selective sst1, sst2, sst5 somatostatin receptors agonists, a somatostatin/dopamine (SST/DA) chimera and bromocriptine on the "clinically non-functioning" pituitary adenomas in vitro

Life Sciences

Volumn 78, Issue 7, 2006, Pages 689-693

  Gruszka, A ^a   Kunert Radek, J ^a   Radek, A ^a   Pisarek, H ^a   Taylor, J ^b   Dong, J Z ^b   Culler, M D ^b   Pawlikowski, M ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

^b IPSEN   (France)

Author keywords

Bromocriptine; Non functioning pituitary adenomas; Somatostatin analogs; Somatostatin receptors; Somatostatin dopamine chimera

Indexed keywords

BIM 23023; BIM 23120; BIM 23206; BIM 23926; BIM 23A387; BIM 53097; BROMOCRIPTINE; COLLAGENASE; DOPAMINE 2 RECEPTOR; DOPAMINE RECEPTOR STIMULATING AGENT; HORMONE RECEPTOR STIMULATING AGENT; HYPOPHYSIS HORMONE; PARAFFIN; SOMATOSTATIN DERIVATIVE; SOMATOSTATIN RECEPTOR 1; SOMATOSTATIN RECEPTOR 2; SOMATOSTATIN RECEPTOR 2A; SOMATOSTATIN RECEPTOR 2B; SOMATOSTATIN RECEPTOR 3; SOMATOSTATIN RECEPTOR 4; SOMATOSTATIN RECEPTOR 5; SST 14; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CELL SUSPENSION; CHIMERA; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOPHYSIS ADENOMA; HYPOPHYSIS TUMOR; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; TUMOR CELL;

ADENOMA; ADULT; AGED; BROMOCRIPTINE; CELL SURVIVAL; DOPAMINE AGONISTS; DRUG SYNERGISM; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; PITUITARY NEOPLASMS; RECEPTORS, DOPAMINE; RECEPTORS, SOMATOSTATIN; RECOMBINANT FUSION PROTEINS; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL;

EID: 29244481659     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2005.05.061     Document Type: Article

References (14)

1. F. Alderton, T.P. Fan, M. Schindler, and P.P. Humphrey Rat somatostatin sst2(a) and sst2(b) receptor isoforms mediate opposite effects on cell proliferation British Journal of Pharmacology 125 8 1998 1630 1633
2. A. Colao, M. Filippella, C. Di Somma, S. Manzi, F. Rota, R. Pivonello, M. Gaccione, M. De Rosa, and G. Lombardi Somatostatin analogs in treatment of non-growth hormone-secreting pituitary adenomas Endocrine 20 3 2003 279 283
3. T.W.A. De Bruin, D.J. Kwekkeboom, J.W. van't Verlaat, J.-C. Reubi, E.P. Krenning, S.W.J. Lamberts, and R.J.M. Croughs Clinically nonfunctioning pituitary adenoma and octreotide response to long term high dose treatment and studies in vitro Journal of Clinical Endocrinology and Metabolism 75 5 1992 1310 1317
4. A. Gruszka, M. Pawlikowski, and J. Kunert-Radek Anti-tumoral action of octreotide and bromocriptine on the experimental rat prolactinoma: anti-proliferative and pro-apoptotic effects Neuro-Endocrinology Letters 22 5 2001 343 348
5. L. Katznelson, J.M. Alexander, and A. Klibanski Clinically nonfunctioning pituitary adenomas Journal of Clinical Endocrinology and Metabolism 76 5 1993 1089 1094
6. J. Kunert-Radek, A. Radek, A. Gruszka, and M. Pawlikowski Immunohistochemical investigation of clinically nonfunctioning pituitary tumors as a prognostic factor of tumor recurrence Proceedings of 12th International Congress of Endocrinology, Lisbon, Portugal, August 31-September 4, 2004. Medimond S.r.l., Bologna, Italy 2004 1229 1233
7. T. Mosmann Rapid colorimetric method assay for cell growth and survival: application to proliferation and cytotoxic assays Journal of Immunological Methods 65 1-2 1983 55 63
8. F.R. Nobels, W.W. de Herder, W.M. van den Brink, D.J. Kwekkeboom, L.J. Hoffland, F.H. Zuyderwijk, F.H. de Long, and S.W.J. Lamberts Long-term treatment with the dopamine agonist quinagolide of patients with clinically non-functioning pituitary adenoma European Journal of Endocrinology 143 5 2000 615 621
9. M. Pawlikowski, J. Kunert-Radek, and A. Radek Gonadotropinoma-a frequent subtype of the pituitary adenoma Endokrynologia Polska-Polish Journal of Endocrinology 51 1 2000 77 81
10. M. Pawlikowski, H. Pisarek, J. Kunert-Radek, and A. Radek Immunohistochemical detection of somatostatin receptor subtypes in "clinically nonfunctioning" pituitary adenomas Endocrine Pathology 14 3 2003 231 238
11. R. Pivonello, C. Matrone, M. Filippella, L.M. Cavallo, C. Di Somma, P. Cappabianca, A. Colao, L. Annunziato, and G. Lomabardi Dopamine receptor expression and function in clinically nonfunctioning pituitary tumors: comparison with the effectiveness of cabergoline treatment Journal of Clinical Endocrinology and Metabolism 89 4 2004 1647 1648
12. S.G. Ren, S. Kim, J. Taylor, J. Dong, J.P. Moreau, M.D. Culler, and S. Melmed Suppression of rat and human growth hormone and prolactin by a novel somatostatin/dopaminergic chimeric ligand Journal of Clinical Endocrinology and Metabolism 88 11 2003 5414 5421
13. A. Saveanu, E. Lavaque, G. Gunz, A. Barlier, S. Kim, J.E. Taylor, M.D. Culler, A. Enjalbert, and P. Jaquet Demonstration of enhanced potency of a chimeric somatostatin/dopamine molecule, BIM-23A387, in suppressing growth hormone and prolactin secretion from human pituitary somatotroph adenoma cells Journal of Clinical Endocrinology and Metabolism 87 12 2002 5545 5552
14. A. Warnet, A.G. Harris, E. Renard, D. Martin, A. James-Deidier, and P. Chaumet-Riffaud A prospective multicenter trial of octreotide in 24 patients with visual defects caused by nonfunctioning and gonadotropin-secreting pituitary adenomas Neurosurgery 41 4 1997 786 795