Identification and quantitative determination of benproperine metabolites in human plasma and urine by liquid chromatography-tandem mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 830, Issue 1, 2006, Pages 71-80

  Li, Yan ^a   Sun, Yuming ^a   Dong, Yu ^a   Zhang, Yifan ^a   Zhong, Dafang ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

3 Hydroxybenproperine; 4 Hydroxybenproperine; Benproperine

Indexed keywords

ACETONITRILE; IONIZATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITES; PHARMACOKINETICS; SAMPLING;

3-HYDROXYBENPROPERINE; 4-HYDROXYBENPROPERINE; BENPROPERINE; LOWER LIMIT OF QUANTIFICATION (LLOQ);

PLASMAS;

1 [1 METHYL 2 [2 (PHENYLMETHYL)PHENOXY]ETHYL] 3 PIPERIDINOL; 1 [1 METHYL 2 [2 (PHENYLMETHYL)PHENOXY]ETHYL] 4 PIPERIDINOL; ACETONITRILE; BENPROPERINE; DEXTROMETHORPHAN; DRUG METABOLITE; FORMIC ACID; UNCLASSIFIED DRUG; WATER;

ACCURACY; ADULT; ARTICLE; BLOOD ANALYSIS; FLOW RATE; HUMAN; HUMAN EXPERIMENT; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MALE; NORMAL HUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; STANDARD; TANDEM MASS SPECTROMETRY; URINALYSIS;

ANTITUSSIVE AGENTS; BENZHYDRYL COMPOUNDS; CALIBRATION; CHROMATOGRAPHY, LIQUID; HUMANS; PIPERIDINES; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 29244465059     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2005.10.011     Document Type: Article

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