Impaired antioxidant defense at the onset of psychosis

Schizophrenia Research

Volumn 19, Issue 1, 1996, Pages 19-26

  Mukherjee, Sukdeb ^a,b   Mahadik, Sahebarao P ^a,b   Scheffer, Russell ^c   Correnti, Elizabeth E ^c   Kelkar, Hemant ^a,b  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c EISENHOWER ARMY MEDICAL CENTER   (United States)

Author keywords

Catalase; Glutathione peroxidase; Oxyradical; Schizophrenia; Superoxide dismutase

Indexed keywords

ANTIOXIDANT; CATALASE; GLUTATHIONE PEROXIDASE; OXYGEN RADICAL; SUPEROXIDE DISMUTASE;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DEFENSE MECHANISM; ENZYME ACTIVITY; ERYTHROCYTE; FEMALE; HUMAN; MALE; PRIORITY JOURNAL; PSYCHOSIS; SCHIZOPHRENIA;

EID: 0029925336     PISSN: 09209964     EISSN: None     Source Type: Journal    
DOI: 10.1016/0920-9964(95)00048-8     Document Type: Article

References (65)

1. Abdalla, D.S.P., Manteiro, H.P., Olivera, J.A.C. and Bechara, C.H. (1986) Activities of superoxide dismutase and glutathione peroxidase in schizophrenic and manic depressive patients. Clin. Chem. 32, 805-807.
2. Adler, L.A., Peselow, E., Rotrosen, J., Duncan, E., Lee, M., Rosenthal, M. and Angrist, B. (1993) Vitamin E treatment of tardive dyskinesia. Am. J. Psychiatry 150, 1405-1407.
3. Aebi, H. (1984) Catalase in vitro. In Packer, L. (Ed.) Methods in Enzymology. Vol. 105. Academic Press, New York, pp. 121-126.
4. Allen, R.G. (1991) Oxygen-reactive species and antioxidant responses during development: the metabolic paradox of cellular differentiation. Proc. Soc. Exptl. Biol. Med. 196, 117-129.
5. Anneren, G., Gardner, A. and Lundin, T. (1986) Increased glutathione peroxidase activity in erythrocytes in patients with Alzheimer's disease/senile dementia of Alzheimer's type. Acta Neurol. Scand. 73, 586-589.
6. Balter, A.M. (1961) Glucose tolerance curves in neuropsychiatric patients. Diabetes 10, 100-104.
7. Bourre, J.-M., Francois, M., Youyou, A., Dumont, O., Piciotti, M., Pascal, G. and Durand, G. (1989) The effects of dietary α-linolenic acid on the composition of nerve membranes, enzymatic activity, amplitude of electrophysiological parameters, resistance to poisons and performance of learning tasks in rats. J. Nutr. 119, 1880-1892.
8. Buckman, T.D., Kling, A.S., Eiduson, S., Sutphin, M.S. and Steinberg, A. (1987) Glutathione peroxidase and CT scan abnormalities in schizophrenia. Biol. Psychiatry 22, 349-356.
9. Cadet, J.L. and Lohr, J.B. (1987) Free radicals and the developmental pathology of schizophrenic burnout. Integr. Psychiatry 5, 40-48.
10. Cadet, J.L., Lohr, J.B. and Jeste, D.V. (1986) Free radicals and tardive dyskinesia. TINS. 9, 107-108.
11. Cadet, J.L. and Perumal, A.S. (1990) Chronic treatment with prolixine causes oxidative stress in rat brain. Biol. Psychiatry 28, 738-740.
12. Cannon-Spoor, H.E., Potkin, S.G. and Wyatt, R.J. (1982) Measurement of premorbid adjustment in chronic schizophrenia. Schizophr. Bull. 8, 470-484.
13. Cohen, M.R., Sailer, V., McAmis, B. and Jenkins, P. (1986) Superoxide dismutase activity in fibroblasts from patients with schizophrenia. Biol. Psychiatry. 21, 322-324.
14. Collier, A., Wilson, R., Bradley, H., Thomson, J.A. and Small, M. (1990) Free radical activity in type 2 diabetes. Diab. Med. 7, 27-30.
15. Crawford, M.A. (1993) The role of essential fatty acids in neural development: implications for perinatal nutrition. Am. J. Clin. Nutr. 57 (suppl), 703S-710S.
16. Delacourte, A., Defossez, A., Ceballos, I., Nicole, I. and Sinet, P.M. (1988) Preferential localization of copper zinc superoxide dismutase in the vulnerable cortical neurons in Alzheimer's disease. Neurosci. Lett. 92, 247-253.
17. Elkashef, A.M., Ruskin, P.E., Bacher, N. and Barrett, D. (1990) Vitamin E in the treatment of tardive dyskinesia. Am. J. Psychiatry 147, 505-506.
18. Flohe, L. and Gunzler, W.A. (1984) Assays of glutathione peroxidase. In: Packer, L. (Ed.) Methods in Enzymology. Vol. 105. Academic Press, New York, pp. 114-121
19. Fried, R. (1975) Enzymatic and nonenzymatic assay of superoxide dismutase. Biochemie 57, 657-660.
20. Glazov, V.A. and Mamzev, V.P. (1976) Catalase in the blood and leucocytes in patients with nuclear schizophrenia. Zh. Neuropatol. Psikhiatr. 4, 549-552.
21. Glen, A.I.M., Glen, E.M.T., Horrobin, D.F., Vaddadi, K.S., Spellman, M., Morse-Fisher, N., Ellis, K., and Skinner, F.K. (1994) A red cell membrane abnormality in a subgroup of schizophrenic patients: Evidence for two diseases. Schizophr. Res. 12, 53-61.
22. Golse, B., Debray, Q., Puget, K. and Michelson, A.M. (1978) Dosages érythrocytaires de la superoxyde dismutases 1 et de la glutathion peroxydase dans les schizophrénies de l'adulte. Nouvelle Presse Med. 7, 2070-2071.
23. Goodman, A.B. (1994) Medical conditions in Ashkenazi schizophrenic pedigrees. Schizophr. Bull. 20, 507-518.
24. Halliwell, B. and Gutteridge, J.M.C. (1989) Free Radicals in Biology and Medicine. 2nd Ed. Clarendon Press, Oxford.
25. Hogg, N., Parthasarathy, S. and Kalyanaraman, B. (1993) Inhibition of low-density lipoprotein oxidation by nitric oxide. Free Rad Biol Med 15, 495.
26. Kramer, K., Voss, H.-P., Grimbergen, J.A., Timmerman, H. and Bast, A. (1987) The effect of ischemia and recirculation, hypoxia and recovery on anti-oxidant factors and b-adrenoreceptor density. Biochem. Biophys. Res. Commun. 149, 568-579.
27. Lohr, J.B., Cadet, J.L., Lohr, M.A., Jeste, D.V. and Wyatt, R.J. (1987) Alpha-tocopherol in tardive dyskinesia. Lancet i, 913-914.
28. Lohr, J.B., Kuczenski, R., Bracha, H.S., Moir, M. and Jeste, D.V. (1990) Increased indices of free radical activity in the cerebrospinal fluid of patients with tardive dyskinesia. Biol. Psychiatry 28, 535-539.
29. Mahadik, S.P, Mukherjee, S., Reddy, R., Korenovsky, A. and Makar, T. (1992) Brain insulin resistance and deregulation of antioxidant enzymes in a rodent model of NIDDM. Biol. Psychiatry 31, 219A.
30. Mahadik SP, Mukherjee S, Correnti EE, Scheffer R: (1995) Elevated levels of lipid peroxidation products in plasma of drug-naive patients at the onset of psychosis. Schizophr. Res. 15, 66.
31. Mattson, M.P., Murrain, M., Guthrie, P.B., and Kater, S.B. (1989) Fibroblast growth factor and glutamate: opposing roles in the generation and degeneration of hippocampal neuroarchitecture. J. Nerosci. 9, 3728-3740.
32. Mellor JE, Laugharne J, Peet M: Eicosapentanoic acid and schizophrenia. Paper presented at the XIXth Collegium Internationale Neuropsycho-Pharmacologicum, Washington, DC, June 1994.
33. Michelson, A.M., Puget, K., Durosay, P. and Bouneau, J.C. (1977) Clinical aspects of the dosage of erythrocuprein. In: Michelson, A.M., McCord, J.M., and Fridovich, I. (Eds.) Superoxide and Superoxide Dismutase. Academic Press, London, pp. 467-499.
34. Miguel, A., Quintanilha, A.T. and Weber, H. (Eds) (1989) CRC Handbook of Free Radicals and Antioxidants in Biomedicine. Vols. I-III. CRC Press Inc, Boca Raton, FL, 1989.
35. Mukherjee, S., Schnur, D.B. and Reddy, R. (1989) Family history of type 2 diabetes in schizophrenic patients. Lancet i, 495.
36. Mukherjee, S., Reddy, R. and Schnur, D.B. (1991) Developmental model of negative syndromes in schizophrenia. In: Greden, J., Tandon, R. (Eds.) Negative Schizophrenic Syndromes: Pathophysiology and Clinical Implications. American Psychiatric Press, Washington, DC, pp. 175-185.
37. Mukherjee, S. (1995) High prevalence of type II diabetes in schizophrenic patients. Schizophr. Res. 15, 195.
38. Mukherjee, S., Mahadik, S.P., Scheffer, R. and Correnti, E.E. (1995) Early relapse after recovery from a first episode of psychosis: possible role of oxidative stress. Schizophr. Res. 15, 159 (abstract).
39. Mukherjee, S., Decina, P., Bocola, V., Saraceni, F. and Scapicchio, P.L. (1996) Diabetes mellitus in schizophrenic patients. Compr. Psychiatry. 37, 68-73.
40. Murthy, J.N., Laev, H., Karpiak, S. and Mahadik, S.P. (1989) Enzymes of oxyradical metabolism after haloperidol treatment of rat. Soc. Neurosci. Abstr. 15, 139.
41. Neuringer, M., Connor, W.E., Lin, D.S., Barstad, L. and Luck, S. (1986) Biochemical and functional effect of prenatal and postnatal ω3 fatty acid deficiency on retina and brain in rhesus monkeys. Proc. Natl. Acad. Sci. USA 83, 4021-4025.
42. Nishikimi, M., Appaji Rao, N. and Yagi, K. (1972) The occurrence of superoxide anion in the reaction of reduced phenagine methosulphate and molecular oxygen. Biochem. Biophys. Res. Comm. 46, 849-854.
43. Pall, H.S., Williams, A.C., Blake, D.R. and Lunec, J. (1987) Evidence of enhanced lipid peroxidation in the cerebrospinal fluid of patients taking phenothiazines. Lancet ii, 596-597.
44. Peet, M., Laugharne, J., Rangarajan, N. and Reynolds, G.P. (1993) Tardive dyskinesia, lipid peroxidation, and sustained amelioration with vitamin E treatment. Int. Clin. Psychopharmacol. 8, 151-153.
45. Prilipko, L.L. (1984) Activation of lipid peroxidation under stress and in schizophrenia. In: Kemali, D., Morozov, P.V. and Toffano, G. (Eds) New Research Strategies in Biological Psychiatry. Biological Psychiatry-New Perspectives: 3. John Libbey, London.
46. Reddy, R., Mahadik, S.P., Mukherjee, S. and Murthy, J.N. (1991) Enzymes of the antioxidant defense system in chronic schizophrenic patients. Biol. Psychiatry 30, 409-412.
47. Reddy, R., Mahadik, S.P., Mukherjee, S. and Makar, T. (1992) Neuroleptic effects on the enzymes of the antioxidant defense system in manic and schizophrenic patients. Biol. Psychiatry 31, 248A.
48. Reddy, R., Kelkar, H., Mahadik, S.P. and Mukherjee, S. (1993) Abnormal erythrocyte catalase activity in schizophrenic patients. Schizophr. Res. 9, 227.
49. Reddy, R., Kelkar, H., Mahadik, S. and Mukherjee, S. (1994) Free radicals and neurological signs in chronic schizophrenic patients. Biol. Psychiatry 35, 699-700.
50. Rosen, D.R., Siddiqui, T., Patterson, D., Figlewica, D.A. et al. (1993) Mutations in CuZn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 362, 59-62.
51. Roy, D., Pathak, D.N. and Singh, R. (1984) Effects of chlorpromazine on the activities of antioxidant enzymes and lipid peroxidation in various regions of aging rat brain. J. Neurochem. 42, 628-633.
52. Scapicchio, P.L., Decina, P., Mukherjee, S. and Caracci, G. (1991) Effects of α-tocopherol on persistent tardive dyskinesia in elderly schizophrenic patients. Ital. J. Psychiatr. Behav. Sci. 1, 111-114.
53. Sinet, P.M. (1982) Metabolism of oxygen derivatives in Down's syndrome. Ann. N.Y. Acad. Sci. 396, 83-94.
54. Sinet, P.M., Debray, Q., Carmagnol, F., Pelicier, Y., Nicole, A. and Jerome, H. (1983) Normal erythrocyte SOD values in two human diseases: Schizophrenia and cystic fibrosis. In: Greenwald, R.A. and Cohen, G. (Eds.) Oxy-Radicals and their Scavenger Systems. Vol. II. Cellular and Medical Aspects. Elsevier, Amsterdam, pp. 302-304.
55. Stevens, C., Goldblatt, M., and Freedman, J.C. (1975) Lack of erythrocyte superoxide dismutase change during human senescence. Mech. Ageing Dev. 4, 415-417.
56. Stoklasova, A., Zapletalek, M., Kudrnova, K. and Randova, Z. (1986) Glutathione peroxidase activity of blood in chronic schizophrenics. Sborniku Vedeckych Praci Lekarske Fakulty UK v Hradci Kralove 29 (suppl), 103-108.
57. Szabo, L., Lajko, K., Barabas, K. and Matkovics, B. (1983) Effects of neuroleptics on lipid peroxidation and peroxide metabolism enzyme activities in various discrete areas of the rat brain. Chem. Pharmacol. 14, 537-539.
58. Tabata, H., Kikuoka, M., Kikuoka, H., et al. (1987) Characteristics of diabetes mellitus in schizophrenic patients. J. Med. Assoc. Thailand 70 (suppl 2), 90-93.
59. Toth, K.M., Berger, E.M., Beehler, C.J. and Repine, J.E. (1986) Erythrocytes from smokers contain more glutathione and catalase and protect endothelial cells from hydrogen peroxide better than do erythrocytes from nonsmokers. Am. Rev. Respir. Dis. 134, 281-284.
60. Vaddadi, K.S. and Gilleard, C.J. (1990) Essential fatty acids, tardive dyskinesia, and schizophrenia. In Horrobin, D.R. (ed) Omega-6 Essential Fatty Acids: Pathophysiology and Roles in Clinical Medicine. Alan R. Liss, Inc., New York, pp. 333-343.
61. Wainwright, P.E. (1992) Do essential fatty acids play a role in brain and behavioral development? Neurosci Biobehav Rev 16, 193-205.
62. Yamamoto, I., Adachi, N., Kurogochi, Y. and Tsijimoto, A. (1960) Effects of chlorpromazine on enzymic reactions involving metal ions. Jpn. J. Pharmacol. 10, 38-46.
63. Yamamoto, N., Saitoh, M., Moriuchi, A., Nomura, M. and Okuyama, H. (1987) Effect of dietary α-linolenate/ linoleate balance on brain lipid compositions and learning ability of rats. J. Lipid Res. 28, 144-151.
64. Yao, J.K., van Kammen, D.P., and Welker, J.A. (1994) Red blood cell membrane dynamics in schizophrenia. II. Fatty acid composition. Schizophr. Res. 13, 217-226.
65. Zelman, F.P., Thienhaus, O.J. Bosmann, H.B. (1989) Superoxide dismutase activity in Alzheimer's disease: possible mechanism for paired helical filament formation. Brain Res. 476, 160-162.