Hyperglycemia among persons with hepatitis C: Not the classical diabetic phenotype

Diabetes Research and Clinical Practice

Volumn 71, Issue 1, 2006, Pages 68-74

  Behrendt, Carolyn E ^a   Ruiz, Rolando B ^a  

^a PFIZER INC   (United States)

Author keywords

Diabetes mellitus, type 2; Hepatitis C virus; Hyperglycemia; Impaired fasting glucose; United States epidemiology

Indexed keywords

ALANINE AMINOTRANSFERASE; CHOLESTEROL; FERRITIN; GLOBULIN; GLUCOSE;

ABNORMALLY HIGH SUBSTRATE CONCENTRATION IN BLOOD; ADULT; AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; B LYMPHOCYTE; CLONE; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; DIABETES MELLITUS; DISEASE ASSOCIATION; DISEASE COURSE; FAMILY HISTORY; FEMALE; GROUPS BY AGE; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; HYPERFERRITINEMIA; HYPERGLYCEMIA; HYPERTENSION; HYPOCHOLESTEROLEMIA; IMPAIRED GLUCOSE TOLERANCE; ISCHEMIC HEART DISEASE; LIVER DISEASE; LIVER FIBROSIS; MAJOR CLINICAL STUDY; MALE; OBESITY; PHENOTYPE; SEROPREVALENCE; THROMBOCYTE COUNT;

ADULT; AGED; AGED, 80 AND OVER; ALANINE TRANSAMINASE; CHOLESTEROL; CORONARY DISEASE; DIABETES MELLITUS, TYPE 2; FEMALE; FERRITINS; GLOBULINS; HEPACIVIRUS; HEPATITIS C; HUMANS; HYPERGLYCEMIA; LIVER; MALE; MIDDLE AGED; OVERWEIGHT; PLATELET COUNT; SEROEPIDEMIOLOGIC STUDIES;

EID: 29244461999     PISSN: 01688227     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.diabres.2005.04.005     Document Type: Article

References (26)

1. S.H. Mehta, F.L. Brancati, S.A. Strathdee, J.S. Pankow, D. Netski, and J. Coresh Hepatitis C virus infection and incident type 2 diabetes Hepatology 38 2003 50 56
2. S.H. Mehta, R.D. Moore, D.L. Thomas, R.E. Chaisson, and M.S. Sulkowski The effect of HAART and HCV infection on the development of hyperglycemia among HIV-infected persons JAIDS 33 2003 577 584
3. Y. Shintani, H. Fujie, H. Miyoshi, T. Tsutsumi, K. Tsukamoto, and S. Kimura Hepatitis C virus infection and diabetes: direct involvement of the virus in the development of insulin resistance Gastroenterology 126 2004 840 848
4. A. Antonelli, C. Ferri, P. Fallahi, M. Sebastiani, C. Nesti, and L. Barani Type 2 diabetes in hepatitis C-related mixed cryoglobulinaemia patients Rheumatology (Oxford) 43 2004 238 240
5. R. Simo, C. Hernandez, J. Genesca, R. Jardi, and J. Mesa High prevalence of hepatitis C virus infection in diabetic patients Diabetes Care 19 1996 998 1000
6. M.B. Streiff, S. Mehta, and D.L. Thomas Peripheral blood count abnormalities among patients with hepatitis C in the United States Hepatology 35 2002 947 952
7. C.O. Zein, C. Levy, A. Basu, and N.N. Zein Chronic hepatitis C and type II diabetes mellitus: a prospective cross-sectional study Am. J. Gastroenterol. 100 2005 48 55
8. C. Hernandez, J. Genesca, J. Ignasi Esteban, L. Garcia, and R. Simo Relationship between iron stores and diabetes mellitus in patients infected by hepatitis C virus: a case-control study Med. Clin. (Barc.) 115 2000 21 22 (in Spanish)
9. M.A. Metwally, C.O. Zein, and N.N. Zein Clinical significance of hepatic iron deposition and serum iron values in patients with chronic hepatitis C infection Am. J. Gastroenterol. 99 2004 286 291
10. National Center for Health Statistics, Plan and Operation of the Third National Health and Nutrition Examination Survey, 1988-1994, National Center for Health Statistics, Hyattsville, MD, 1994 (DHHS publ. no. PHS 94-1308, available from URL: http://www.cdc.gov/nchs/data/series/sr_01/sr01_032.pdf, accessed 15 June 2004).
11. E.W. Gunter, B.G. Lewis, S.M. Koncikowski, Laboratory Procedures Used for the Third National Health and Nutrition Examination Survey (NHANES III), 1988-1994, National Center for Environmental Health, Atlanta, GA, and National Center for Health Statistics, Hyattsville, MD, 1996 (available from URL: http://www.cdc.gov/nchs/data/nhanes/nhanes3/cdrom/nchs/manuals/labman.pdf, accessed 15 June 2004).
12. American Diabetes Association Diagnosis and classification of diabetes mellitus Diabetes Care 27 Suppl. 1 2004 S5 S10
13. Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults, Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel) JAMA 285 2001 2486 2497
14. G.A. Rose, H. Blackburn, R.F. Gillum, and R.J. Prineas Cardiovascular Survey Methods 2nd ed. 1982 World Health Organization Geneva
15. C.E. Ruhl, and J.E. Everhart Leptin concentrations in the United States: relations with demographic and anthropometric measures Am. J. Clin. Nutr. 74 2001 295 301
16. J.M. Clark, F.L. Brancati, and A.M. Diehl The prevalence and etiology of elevated aminotransferase levels in the United States Am. J. Gastroenterol. 98 2003 960 967
17. G.N. Ioannou, J.A. Dominitz, N.S. Weiss, P.J. Heagerty, and K.V. Kowdley Racial differences in the relationship between hepatitis C infection and iron stores Hepatology 37 2003 795 801
18. R.L. Stout Hepatitis C prevalence and the significance of liver enzyme elevations in the insurance population J. Insur. Med. 29 1997 187 191
19. C. Cicognani, M. Malavolti, A.M. Morselli-Labate, L. Zamboni, C. Sama, and L. Barbara Serum lipid and lipoprotein patterns in patients with liver cirrhosis and chronic active hepatitis Arch. Int. Med. 157 1997 792 796
20. D. Gasparotto, V. De Re, and M. Boiocchi Hepatitis C virus, B-cell proliferation and lymphomas Leuk. Lymphoma 43 2002 747 751
21. T. Nagamine, T. Ohtuka, K. Takehara, T. Arai, H. Takagi, and M. Mori Thrombocytopenia associated with hepatitis C viral infection J. Hepatol. 24 1996 135 140
22. P. Lamprecht, O. Gutzeit, E. Csernok, A. Gause, G. Longombardo, and A.L. Zignego Prevalence of ANCA in mixed cryoglobulinemia and chronic hepatitis C virus infection Clin. Exp. Rheumatol. 21 Suppl. 32 2003 S89 S94
23. T.V. Inglesby, R. Rai, J. Astemborski, L. Gruskin, K.E. Nelson, D. Vlahov, and D.L. Thomas A prospective, community-based evaluation of liver enzymes in individuals with hepatitis C after drug use Hepatology 29 1999 590 596
24. H. Knobler, T. Zhornicky, A. Sandler, N. Haran, Y. Ashur, and A. Schattner Tumor necrosis factor-alpha-induced insulin resistance may mediate the hepatitis C virus-diabetes association Am. J. Gastroenterol. 98 2003 2751 2756
25. A. Erhardt, A. Maschner-Olberg, C. Mellenthin, G. Kappert, O. Adams, and A. Donner HFE mutations and chronic hepatitis C: H63D and C282Y heterozygosity are independent risk factors for liver fibrosis and cirrhosis J. Hepatol. 38 2003 335 342
26. S.G. Gehrke, W. Stremmel, I. Mathes, H.D. Riedel, K. Bents, and B. Kallinowski Hemochromatosis and transferrin receptor gene polymorphisms in chronic hepatitis C: impact on iron status, liver injury and HCV genotype J. Mol. Med. 81 2003 780 787