Effects of oxygen and carbon dioxide on human retinal circulation: An investigation using blue field simulation and scanning laser ophthalmoscopy

Acta Ophthalmologica Scandinavica

Volumn 83, Issue 6, 2005, Pages 705-710

  Tomic, Lidija ^a   Bjärnhall, Gunilla ^a   Mäepea, Olav ^a   Sperber, Göran O ^a   Alm, Albert ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

Arteriovenous passage time; Carbon dioxide; Macular blood flow; Mean transit time; Oxygen; Vessel diameter

Indexed keywords

CARBON DIOXIDE; OXYGEN;

ADULT; ARTICLE; BLOOD VESSEL DIAMETER; BLUE FIELD SIMULATION; CONTROLLED STUDY; FEMALE; FLUORESCENCE ANGIOGRAPHY; HUMAN; HUMAN EXPERIMENT; LEUKOCYTE FUNCTION; MALE; MEAN TRANSIT TIME; NORMAL HUMAN; PRIORITY JOURNAL; PROVOCATION TEST; RETINA ARTERY; RETINA BLOOD FLOW; RETINA MACULA LUTEA; RETINA VEIN; SCANNING LASER OPHTHALMOSCOPY; SIMULATION; TECHNIQUE; VELOCITY; VISUAL SYSTEM PARAMETERS;

ADULT; BLOOD FLOW VELOCITY; BLOOD GAS ANALYSIS; BLOOD PRESSURE; CARBON DIOXIDE; FEMALE; FLUORESCEIN ANGIOGRAPHY; HEART RATE; HUMANS; LASERS; LEUKOCYTES; MALE; OPHTHALMOSCOPY; OXYGEN; REGIONAL BLOOD FLOW; RETINAL VESSELS;

EID: 29244456125     PISSN: 13953907     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0420.2005.00522.x     Document Type: Article

References (27)

1. Alm A & Bill A (1972): The oxygen supply to the retina. II. Effects of high intraocular pressure and of increased arterial carbon dioxide tension on uveal and retinal blood flow in cats. A study with radioactively labelled microspheres including flow determinations in brain and some other tissues. Acta Physiol Scand 84: 306-319.
2. Arend O, Harris A, Sponsel WE, Remky A, Reim M & Wolf S (1995): Macular capillary particle velocities: a blue field and scanning laser comparison. Graefes Arch Clin Exp Ophthalmol 233: 244-249.
3. Bjärnhall G, Mäepea O, Sperber GO, Lindén C, Mönestam E & Alm A (2002): Analysis of mean retinal transit time from fluorescein angiography in human eyes: normal values and reproducibility. Acta Ophthalmol Scand 80: 652-655. [Erratum in: Acta Ophthalmol Scand 2003 81: 99.]
4. Deutsch TA, Read JS, Ernest JT & Goldstick TK (1983): Effects of oxygen and carbon dioxide on the retinal vasculature in humans. Arch Ophthalmol 101: 1278-1280.
5. 2-breathing in humans. Eur J Ophthalmol 12: 459-466.
6. Fallon TJ, Maxwell D & Kohner EM (1985): Retinal vascular autoregulation in conditions of hyperoxia and hypoxia using the blue field entoptic phenomenon. Ophthalmology 92: 701-705.
7. Frayser R & Hickam JB (1964): Retinal vascular response to breathing increased carbon dioxide and oxygen concentrations. Invest Ophthalmol 32: 427-431.
8. 2 breathing on retinal blood flow in normals and in patients with background diabetic retinopathy. Curr Eye Res 3: 239-241.
9. Harino S, Grunwald JE, Petrig BJ & Riva CE (1995): Rebreathing into a bag increases human retinal macular blood velocity. Br J Ophthalmol 79: 380-383.
10. Harris A, Arend O, Kopecky K, Caldemeyer K, Wolf S, Sponsel W & Martin B (1994): Physiological perturbation of ocular and cerebral blood flow as measured by scanning laser ophthalmoscopy and colour Doppler imaging. Surv Ophthalmol 38: S81-S86.
11. 2 dependence of retinal arterial and capillary blood velocity. Acta Ophthalmol Scand 73: 421-424.
12. Hickam JB & Frayser R (1965): A photographic method for measuring the mean retinal circulation time using fluorescein. Invest Ophthalmol 4: 876-884.
13. Hickam JB, Sicker HO & Frayser R (1959): Studies of retinal circulation and A-V oxygen difference in man. Trans Am Clin Climatol Assoc 71: 34-44.
14. Kiss B, Polska E, Dorner G et al. (2002): Retinal blood flow during hyperoxia in humans revisited: concerted results using different measurement techniques. Microvasc Res 64: 75-85.
15. Lassen NA & Perl W (1979): Volume/flow or mass/flux ratio (mean transit time). II. Bolus injection. In: Lassen NA & Perl W (eds). Tracer Kinetic Methods in Medical Physiology. New York: Raven Press 76-101.
16. Meier P & Zierler KL (1954): On the theory of the indicator-dilution method for measurement of blood flow and volume. J Appl Physiol 6: 731-744.
17. Pakola SJ & Grunwald JE (1993): Effects of oxygen and carbon dioxide on human retinal circulation. Invest Ophthalmol Vis Sci 34: 2866-2870.
18. Rassam SM, Patel V, Chen HC & Kohner EM (1996): Regional retinal blood flow and vascular autoregulation. Eye 10: 331-337.
19. Riva CE, Grunwald JE & Sinclair SH (1983): Laser Doppler velocimetry study of the effect of pure oxygen breathing on retinal blood flow. Invest Ophthalmol Vis Sci 24: 47-51.
20. Riva CE & Petrig B (1980): Blue field entoptic phenomenon and blood velocity in the retinal capillaries. J Opt Soc Am 70: 1234-1238.
21. Riva CE & Petrig BL (1990): Retinal blood flow: laser Doppler velocimetry and blue field simulation technique. In: Masters B (ed). Non-invasive Diagnostic Techniques in Ophthalmology. New York: Springer-Verlag.
22. 2 on ocular fundus pulsations. Exp Eye Res 63: 351-355.
23. Sperber GO & Alm A (1997): Retinal mean transit time determined with an impulse-response analysis from video fluorescein angiograms. Acta Ophthalmol Scand 75: 532-536.
24. Sponsel WE, DePaul KL & Zetlan SR (1992): Retinal haemodynamic effects of carbon dioxide, hyperoxia and mild hypoxia. Invest Ophthalmol Vis Sci 33: 1864-1869.
25. Stefansson E, Wagner HG & Seida M (1988): Retinal blood flow and its autoregulation measured by intraocular hydrogen clearance. Exp Eye Res 47: 669-678.
26. Tomic L, Maepea O, Sperber GO & Alm A (2001): Comparison of retinal transit times and retinal blood flow: a study in monkeys. Invest Ophthalmol Vis Sci 42: 752-755.
27. Wolf S, Jung F, Kiesewetter H, Korber N & Reim M (1989): Video fluorescein angiography: method and clinical application. Graefes Arch Clin Exp Ophthalmol 227: 145-151.