Development of stealth liposome formulation of 2′-deoxyinosine as 5-fluorouracil modulator: In vitro and in vivo study

Pharmaceutical Research

Volumn 22, Issue 12, 2005, Pages 2051-2057

  Fanciullino, Raphaelle ^a   Giacometti, Sarah ^a   Aubert, Claude ^a   Fina, Frederic ^b   Martin, Pierre Marie ^b   Piccerelle, Philippe ^a   Ciccolini, Joseph ^a  

^a AIX MARSEILLE UNIVERSITY   (France)

^b Laboratoire des Interactions Fonctionnelles en Neuroendocrinologie   (France)

Author keywords

2 deoxyinosine; 5 FU; Liposome; Pharmacokinetics; Thymidylate synthase; Xenografts

Indexed keywords

ANTINEOPLASTIC AGENT; DEOXYINOSINE; FLUOROURACIL; LIPOSOME; THYMIDYLATE SYNTHASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG EFFICACY; DRUG ELIMINATION; DRUG FORMULATION; DRUG MECHANISM; ENCAPSULATION; ENZYME INHIBITION; EX VIVO STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SURVIVAL TIME; TUMOR; TUMOR CELL LINE; TUMOR GROWTH; XENOGRAFT;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG DELIVERY SYSTEMS; DRUG SYNERGISM; ENZYME INHIBITORS; FLUOROURACIL; INOSINE; LASERS; LIPOSOMES; MALE; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; RATS; RATS, WISTAR; SCATTERING, RADIATION; THYMIDYLATE SYNTHASE;

EID: 29244451374     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-005-8355-9     Document Type: Article

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