PTPRV is a key mediator of p53-induced cell cycle exit

Cell Cycle

Volumn 4, Issue 12, 2005, Pages 1703-1705

  Doumont, Gilles ^a   Martoriati, Alain ^a   Marine, Jean Christophe ^a  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

Author keywords

Cell cycle; Contact inhibition; DAN damage; p53; Ptprv

Indexed keywords

PROTEIN P53;

APOPTOSIS; CELL CYCLE; CELL DEATH; CELL GROWTH; CELL PROLIFERATION; DNA BINDING; DNA SEQUENCE; DNA TRANSCRIPTION; GENE; GENE PTPRV; GENETIC CODE; GENETIC STRAIN; HUMAN; MEDIATOR; NONHUMAN; NULL CELL; PROTEIN ANALYSIS; SENESCENCE; SHORT SURVEY;

EID: 29244449855     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.4.12.2207     Document Type: Short Survey

References (16)

1. 1 checkpoint failure and increased tumor susceptibility in mice lacking the novel p53 target Ptprv. EMBO J 2005; 24:3093-103.
2. Martoriati A, Doumont G, Alcalay M, Bellefroid E, Pelicci PG, Marine JC. dapk1, encoding an activator of a p19ARF-p53 mediated apoptotic checkpoint, is a transcription target of p53. Oncogene 2005; 24:1461-6.
3. Migliorini D, Denchi EL, Danovi D, Jochemsen A, Capillo M, Gobbi A, Helin K, Pelicci PG, Marine JC. Mdm4 (Mdmx) regulates p53-induced growth arrest and neuronal cell death during early embryonic mouse development. Mol Cell Biol 2002; 22:5527-38.
4. Hoh J, Jin S, Parrado T, Edington J, Levine AJ, Ott J. The p53MH algorithm and its application in detecting p53-responsive genes. Proc Natl Acad Sci USA 2002; 99:8467-72.
5. Dacquin R, Mee PJ, Kawaguchi J, Olmsted-Davis EA, Gallagher JA, Nichols J, Lee K, Karsenty G, Smith A. Knock-in of nuclear localised beta-galactosidase reveals that the tyrosine phosphatase Ptprv is specifically expressed in cells of the bone collar. Dev Dyn 2004; 229:826-34.
6. Jacks T, Remington L, Williams BO, Schmitt EM, Halachmi S, Bronson RT, Weinberg RA. Tumor spectrum analysis in p53-mutant mice. Curr Biol 1994; 4:1-7.
7. El-Deiry WS, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, Lin D, Mercer WE, Kinzler KW, Vogelstein B. WAF1, a potential mediator of p53 tumor suppression. Cell 1993; 75:817-25.
8. Brugarolas J, Chandrasekaran C, Gordon JI, Beach D, Jacks T, Hannon GJ. Radiation-induced cell cycle arrest compromised by p21 deficiency. Nature 1995; 377:552-57.
9. 1 checkpoint control. Cell 1995; 82:675-684.
10. Pallen CJ, Tong PH. Elevation of membrane tyrosine phosphatase activity in density-dependent growth-arrested fibroblasts. Proc Natl Acad Sci USA 1991; 88:6996-7000.
11. Gaits F, Li RY, Ragab A, Ragab-Thomas JM, Chap H. Increase in receptor-like protein tyrosine phosphatase activity and expression level on density-dependent growth arrest of endothelial cells. Biochem J 1995; 311:97-103.
12. Ostman A, Yang Q, Tonks NK. Expression of DEP-1, a receptor-like protein-tyrosine-phosphatase, is enhanced with increasing cell density. Proc Natl Acad Sci USA 1994; 91:9680-84.
13. Flint AJ, Tiganis T, Barford D, Tonks NK. Development of "substrate-trapping" mutants to identify physiological substrates of protein tyrosine phosphatases. Proc Natl Acad Sci USA 1997; 94:1680-85.
14. Wang Z, Shen D, Parsons DW, Bardelli A, Sager J, Szabo S, Ptak J, Silliman N, Peters BA, van der Heijden MS, Parmigiani G, Yan H, Wang TL, Riggins G, Powell SM, Willson JK, Markowitz S, Kinzler KW, Vogelstein B, Velculescu VE. Mutational analysis of the tyrosine phosphatome in colorectal cancers. Science 2004; 304:1164-66.
15. Ruivenkamp CA, van Wezel T, Zanon C, Stassen AP, Vlcek C, Csikos T, Klous AM, Tripodis N, Perrakis A, Boerrigter L, Groot PC, Lindeman J, Mooi WJ, Meijjer GA, Scholten G, Dauwerse H, Paces V, van Zandwijk N, van Ommen GJ, Demant P. Ptprj is a candidate for the mouse colon-cancer susceptibility locus Scc1 and is frequently deleted in human cancers. Nat Genet 2002; 31:295-300.
16. Cousin W, Courseaux A, Ladoux A, Dani C, Peraldi P. Cloning of hOST-PTP: The only example of a protein-tyrosine phosphatase the function of which has been lost between rodent and human. Biochem. Biophys Res Comm 2004; 321:259-65.