메뉴 건너뛰기




Volumn 10, Issue 6, 2005, Pages 391-397

Early cancers of the skin: Clinical, histopathological, and molecular characteristics

Author keywords

CDKN2A; Gene amplification; Gene mutation; Melanoma in situ; p53; Solar keratosis

Indexed keywords

CYCLIN D1; KI 67 ANTIGEN; PROTEIN P14; PROTEIN P16INK4A; PROTEIN P53; TELOMERASE REVERSE TRANSCRIPTASE;

EID: 29244448273     PISSN: 13419625     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10147-005-0532-7     Document Type: Review
Times cited : (23)

References (44)
  • 1
    • 0014884119 scopus 로고
    • Thickness, cross-sectional areas and depth of invasion in the prognosis of cutaneous melanoma
    • A Breslow 1970 Thickness, cross-sectional areas and depth of invasion in the prognosis of cutaneous melanoma Ann Surg 172 902 908
    • (1970) Ann Surg , vol.172 , pp. 902-908
    • Breslow, A.1
  • 2
    • 0018108412 scopus 로고
    • A multifactorial analysis of melanoma: Prognostic histopathological features comparing Clark's and Breslow's staging methods
    • CM Balch TM Murad SJ Soong 1978 A multifactorial analysis of melanoma: prognostic histopathological features comparing Clark's and Breslow's staging methods Ann Surg 188 732 742
    • (1978) Ann Surg , vol.188 , pp. 732-742
    • Balch, C.M.1    Murad, T.M.2    Soong, S.J.3
  • 3
    • 0027483342 scopus 로고
    • Lessons from tumor progression: The invasive radial growth phase of melanoma is common, incapable of metastasis, and indolent
    • DT Guerry M Synnestvedt DE Elder 1993 Lessons from tumor progression: the invasive radial growth phase of melanoma is common, incapable of metastasis, and indolent J Invest Dermatol 100 342S 345S
    • (1993) J Invest Dermatol , vol.100
    • Guerry, D.T.1    Synnestvedt, M.2    Elder, D.E.3
  • 4
    • 0021876278 scopus 로고
    • Early detection of malignant melanoma: The role of physician examination and self-examination of the skin
    • RJ Friedman DS Rigel AW Kopf 1985 Early detection of malignant melanoma: the role of physician examination and self-examination of the skin CA Cancer J Clin 35 130 151
    • (1985) CA Cancer J Clin , vol.35 , pp. 130-151
    • Friedman, R.J.1    Rigel, D.S.2    Kopf, A.W.3
  • 6
    • 0024407112 scopus 로고
    • N-ras mutations in human cutaneous melanoma from sun-exposed body sites
    • LJ van 't Veer BM Burgering R Versteeg 1989 N-ras mutations in human cutaneous melanoma from sun-exposed body sites Mol Cell Biol 9 3114 3116
    • (1989) Mol Cell Biol , vol.9 , pp. 3114-3116
    • Van Veer 'T, L.J.1    Burgering, B.M.2    Versteeg, R.3
  • 7
    • 18444374405 scopus 로고    scopus 로고
    • Mutations of the BRAF gene in human cancer
    • H Davies GR Bignell C Cox 2002 Mutations of the BRAF gene in human cancer Nature 417 949 954
    • (2002) Nature , vol.417 , pp. 949-954
    • Davies, H.1    Bignell, G.R.2    Cox, C.3
  • 8
    • 0348223934 scopus 로고    scopus 로고
    • NRAS and BRAF mutations arise early during melanoma pathogenesis and are preserved throughout tumor progression
    • K Omholt A Platz L Kanter 2003 NRAS and BRAF mutations arise early during melanoma pathogenesis and are preserved throughout tumor progression Clin Cancer Res 9 6483 6488
    • (2003) Clin Cancer Res , vol.9 , pp. 6483-6488
    • Omholt, K.1    Platz, A.2    Kanter, L.3
  • 9
    • 0036896253 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase activation is an early event in melanoma progression
    • C Cohen A Zavala-Pompa JH Sequeira 2002 Mitogen-activated protein kinase activation is an early event in melanoma progression Clin Cancer Res 8 3728 3733
    • (2002) Clin Cancer Res , vol.8 , pp. 3728-3733
    • Cohen, C.1    Zavala-Pompa, A.2    Sequeira, J.H.3
  • 11
    • 24344487227 scopus 로고    scopus 로고
    • Constitutive activation of the MAPK signaling pathway in acral melanomas
    • M Takata Y Goto N Ichii 2005 Constitutive activation of the MAPK signaling pathway in acral melanomas J Invest Dermatol 125 318 322
    • (2005) J Invest Dermatol , vol.125 , pp. 318-322
    • Takata, M.1    Goto, Y.2    Ichii, N.3
  • 12
    • 0034072726 scopus 로고    scopus 로고
    • Gene amplifications characterize acral melanoma and permit the detection of occult tumor cells in the surrounding skin
    • BC Bastian M Kashani-Sabet H Hamm 2000 Gene amplifications characterize acral melanoma and permit the detection of occult tumor cells in the surrounding skin Cancer Res 60 1968 1973
    • (2000) Cancer Res , vol.60 , pp. 1968-1973
    • Bastian, B.C.1    Kashani-Sabet, M.2    Hamm, H.3
  • 13
    • 0142151099 scopus 로고    scopus 로고
    • Classifying melanocytic tumors based on DNA copy number changes
    • BC Bastian AB Olshen PE LeBoit 2003 Classifying melanocytic tumors based on DNA copy number changes Am J Pathol 163 1765 1770
    • (2003) Am J Pathol , vol.163 , pp. 1765-1770
    • Bastian, B.C.1    Olshen, A.B.2    Leboit, P.E.3
  • 14
    • 29244453341 scopus 로고    scopus 로고
    • Early acral melanoma in situ diagnosed with a dermoscopic features of the parallel ridge pattern
    • (in press)
    • Ishihara Y, Saida T, Miyazaki A, et al. (2005) Early acral melanoma in situ diagnosed with a dermoscopic features of the parallel ridge pattern. Am J Dermatopathol (in press)
    • (2005) Am J Dermatopathol
    • Ishihara, Y.1    Saida, T.2    Miyazaki, A.3
  • 15
    • 27944490882 scopus 로고    scopus 로고
    • Specific dermoscopy patterns and amplifications of the cyclin D1 gene to define histopathologically unrecognizable early lesions of acral melanoma in situ
    • (in press)
    • Yamaura M, Takata M, Miyazaki Y, et al. (2005) Specific dermoscopy patterns and amplifications of the cyclin D1 gene to define histopathologically unrecognizable early lesions of acral melanoma in situ. Arch Dermatol (in press)
    • (2005) Arch Dermatol
    • Yamaura, M.1    Takata, M.2    Miyazaki, Y.3
  • 16
    • 0038456527 scopus 로고    scopus 로고
    • Understanding the progression of melanocytic neoplasia using genomic analysis: From fields to cancer
    • BC Bastian 2003 Understanding the progression of melanocytic neoplasia using genomic analysis: from fields to cancer Oncogene 22 3081 3086
    • (2003) Oncogene , vol.22 , pp. 3081-3086
    • Bastian, B.C.1
  • 17
    • 16844385347 scopus 로고    scopus 로고
    • Melanoma genetics and the development of rational therapeutics
    • Y Chudnovsky PA Khavari AE Adams 2005 Melanoma genetics and the development of rational therapeutics J Clin Invest 115 813 824
    • (2005) J Clin Invest , vol.115 , pp. 813-824
    • Chudnovsky, Y.1    Khavari, P.A.2    Adams, A.E.3
  • 18
    • 0031980540 scopus 로고    scopus 로고
    • Virtually 100% of melanoma cell lines harbor alterations at the DNA level within CDKN2A, CDKN2B, or one of their downstream targets
    • GJ Walker JF Flores JM Glendening 1998 Virtually 100% of melanoma cell lines harbor alterations at the DNA level within CDKN2A, CDKN2B, or one of their downstream targets Genes Chromosomes Cancer 22 157 163
    • (1998) Genes Chromosomes Cancer , vol.22 , pp. 157-163
    • Walker, G.J.1    Flores, J.F.2    Glendening, J.M.3
  • 19
    • 0033560166 scopus 로고    scopus 로고
    • P16INK4a inactivation is not frequent in uncultured sporadic primary cutaneous melanoma
    • A Fujimoto R Morita N Hatta 1999 p16INK4a inactivation is not frequent in uncultured sporadic primary cutaneous melanoma Oncogene 18 2527 2532
    • (1999) Oncogene , vol.18 , pp. 2527-2532
    • Fujimoto, A.1    Morita, R.2    Hatta, N.3
  • 20
    • 0028981085 scopus 로고
    • Loss of expression of the p16/cyclin-dependent kinase inhibitor 2 tumor suppressor gene in melanocytic lesions correlates with invasive stage of tumor progression
    • JA Reed F Loganzo Jr CR Shea 1995 Loss of expression of the p16/cyclin-dependent kinase inhibitor 2 tumor suppressor gene in melanocytic lesions correlates with invasive stage of tumor progression Cancer Res 55 2713 2718
    • (1995) Cancer Res , vol.55 , pp. 2713-2718
    • Reed, J.A.1    Loganzo Jr., F.2    Shea, C.R.3
  • 21
    • 0035881619 scopus 로고    scopus 로고
    • The transcriptional repressor of p16/Ink4a, Id1, is up-regulated in early melanomas
    • D Polsky AZ Young KJ Busam 2001 The transcriptional repressor of p16/Ink4a, Id1, is up-regulated in early melanomas Cancer Res 61 6008 6011
    • (2001) Cancer Res , vol.61 , pp. 6008-6011
    • Polsky, D.1    Young, A.Z.2    Busam, K.J.3
  • 23
    • 0033107970 scopus 로고    scopus 로고
    • Progressive increase in telomerase activity from benign melanocytic conditions to malignant melanoma
    • RD Ramirez S D'Atri E Pagani 1999 Progressive increase in telomerase activity from benign melanocytic conditions to malignant melanoma Neoplasia 1 42 49
    • (1999) Neoplasia , vol.1 , pp. 42-49
    • Ramirez, R.D.1    D'Atri, S.2    Pagani, E.3
  • 24
    • 0036993573 scopus 로고    scopus 로고
    • Melanoma development and progression: A conspiracy between tumor and host
    • MY Hsu F Meier M Herlyn 2002 Melanoma development and progression: a conspiracy between tumor and host Differentiation 70 522 536
    • (2002) Differentiation , vol.70 , pp. 522-536
    • Hsu, M.Y.1    Meier, F.2    Herlyn, M.3
  • 25
    • 0037941546 scopus 로고    scopus 로고
    • P16/cyclin-dependent kinase inhibitor 2A deficiency in human melanocyte senescence, apoptosis, and immortalization: Possible implications for melanoma progression
    • EV Sviderskaya VC Gray-Schopfer SP Hill 2003 p16/cyclin-dependent kinase inhibitor 2A deficiency in human melanocyte senescence, apoptosis, and immortalization: possible implications for melanoma progression J Natl Cancer Inst 95 723 732
    • (2003) J Natl Cancer Inst , vol.95 , pp. 723-732
    • Sviderskaya, E.V.1    Gray-Schopfer, V.C.2    Hill, S.P.3
  • 26
    • 0842347502 scopus 로고    scopus 로고
    • Induction of melanoma phenotypes in human skin by growth factors and ultraviolet B
    • C Berking R Takemoto K Satyamoorthy 2004 Induction of melanoma phenotypes in human skin by growth factors and ultraviolet B Cancer Res 64 807 811
    • (2004) Cancer Res , vol.64 , pp. 807-811
    • Berking, C.1    Takemoto, R.2    Satyamoorthy, K.3
  • 27
    • 20144386401 scopus 로고    scopus 로고
    • Regulation of gene expression in melanoma: New approaches for treatment
    • MC Leslie M Bar-Eli 2005 Regulation of gene expression in melanoma: new approaches for treatment J Cell Biochem 94 25 38
    • (2005) J Cell Biochem , vol.94 , pp. 25-38
    • Leslie, M.C.1    Bar-Eli, M.2
  • 28
    • 20944437231 scopus 로고    scopus 로고
    • The gene expression signatures of melanoma progression
    • C Haqq M Nosrati D Sudilovsky 2005 The gene expression signatures of melanoma progression Proc Natl Acad Sci U S A 102 6092 6097
    • (2005) Proc Natl Acad Sci U S a , vol.102 , pp. 6092-6097
    • Haqq, C.1    Nosrati, M.2    Sudilovsky, D.3
  • 29
    • 0032457472 scopus 로고    scopus 로고
    • Comparison of genetic profiles between primary melanomas and their metastases reveals genetic alterations and clonal evolution during progression
    • R Morita A Fujimoto N Hatta 1998 Comparison of genetic profiles between primary melanomas and their metastases reveals genetic alterations and clonal evolution during progression J Invest Dermatol 111 919 924
    • (1998) J Invest Dermatol , vol.111 , pp. 919-924
    • Morita, R.1    Fujimoto, A.2    Hatta, N.3
  • 30
    • 0033936811 scopus 로고    scopus 로고
    • The nature of solar keratosis: A critical review in historical perspective
    • MR Heaphy Jr AB Ackerman 2000 The nature of solar keratosis: a critical review in historical perspective J Am Acad Dermatol 43 138 150
    • (2000) J Am Acad Dermatol , vol.43 , pp. 138-150
    • Heaphy Jr., M.R.1    Ackerman, A.B.2
  • 31
    • 0028596185 scopus 로고
    • Sunburn and p53 in the onset of skin cancer
    • A Ziegler AS Jonason DJ Leffell 1994 Sunburn and p53 in the onset of skin cancer Nature 372 773 776
    • (1994) Nature , vol.372 , pp. 773-776
    • Ziegler, A.1    Jonason, A.S.2    Leffell, D.J.3
  • 32
    • 0030459428 scopus 로고    scopus 로고
    • Frequent clones of p53-mutated keratinocytes in normal human skin
    • AS Jonason S Kunala GJ Price 1996 Frequent clones of p53-mutated keratinocytes in normal human skin Proc Natl Acad Sci U S A 93 14025 14029
    • (1996) Proc Natl Acad Sci U S a , vol.93 , pp. 14025-14029
    • Jonason, A.S.1    Kunala, S.2    Price, G.J.3
  • 33
    • 0030016929 scopus 로고    scopus 로고
    • Two distinct p53 immunohistochemical patterns in human squamous-cell skin cancer, precursors and normal epidermis
    • ZP Ren F Ponten M Nister 1996 Two distinct p53 immunohistochemical patterns in human squamous-cell skin cancer, precursors and normal epidermis Int J Cancer 69 174 179
    • (1996) Int J Cancer , vol.69 , pp. 174-179
    • Ren, Z.P.1    Ponten, F.2    Nister, M.3
  • 34
    • 0033402753 scopus 로고    scopus 로고
    • Low frequency of genetic change in p53 immunopositive clones in human epidermis
    • H Tabata T Nagano AJ Ray 1999 Low frequency of genetic change in p53 immunopositive clones in human epidermis J Invest Dermatol 113 972 976
    • (1999) J Invest Dermatol , vol.113 , pp. 972-976
    • Tabata, H.1    Nagano, T.2    Ray, A.J.3
  • 35
    • 0035923598 scopus 로고    scopus 로고
    • Escaping the stem cell compartment: Sustained UVB exposure allows p53-mutant keratinocytes to colonize adjacent epidermal proliferating units without incurring additional mutations
    • W Zhang E Remenyik D Zelterman 2001 Escaping the stem cell compartment: sustained UVB exposure allows p53-mutant keratinocytes to colonize adjacent epidermal proliferating units without incurring additional mutations Proc Natl Acad Sci U S A 98 13948 13953
    • (2001) Proc Natl Acad Sci U S a , vol.98 , pp. 13948-13953
    • Zhang, W.1    Remenyik, E.2    Zelterman, D.3
  • 36
    • 13444301578 scopus 로고    scopus 로고
    • UVB-induced apoptosis drives clonal expansion during skin tumor development
    • W Zhang AN Hanks K Boucher 2005 UVB-induced apoptosis drives clonal expansion during skin tumor development Carcinogenesis 26 249 257
    • (2005) Carcinogenesis , vol.26 , pp. 249-257
    • Zhang, W.1    Hanks, A.N.2    Boucher, K.3
  • 37
    • 0029889255 scopus 로고    scopus 로고
    • Genetic change in actinic keratoses
    • I Rehman M Takata YY Wu 1996 Genetic change in actinic keratoses Oncogene 12 2483 2490
    • (1996) Oncogene , vol.12 , pp. 2483-2490
    • Rehman, I.1    Takata, M.2    Wu, Y.Y.3
  • 38
    • 0030031515 scopus 로고    scopus 로고
    • Human epidermal cancer and accompanying precursors have identical p53 mutations different from p53 mutations in adjacent areas of clonally expanded non-neoplastic keratinocytes
    • ZP Ren A Hedrum F Ponten 1996 Human epidermal cancer and accompanying precursors have identical p53 mutations different from p53 mutations in adjacent areas of clonally expanded non-neoplastic keratinocytes Oncogene 12 765 773
    • (1996) Oncogene , vol.12 , pp. 765-773
    • Ren, Z.P.1    Hedrum, A.2    Ponten, F.3
  • 39
    • 0031000631 scopus 로고    scopus 로고
    • Benign clonal keratinocyte patches with p53 mutations show no genetic link to synchronous squamous cell precancer or cancer in human skin
    • ZP Ren A Ahmadian F Ponten 1997 Benign clonal keratinocyte patches with p53 mutations show no genetic link to synchronous squamous cell precancer or cancer in human skin Am J Pathol 150 1791 1803
    • (1997) Am J Pathol , vol.150 , pp. 1791-1803
    • Ren, Z.P.1    Ahmadian, A.2    Ponten, F.3
  • 41
    • 0030814353 scopus 로고    scopus 로고
    • Sunlight and the onset of skin cancer
    • DE Brash 1997 Sunlight and the onset of skin cancer Trends Genet 13 410 414
    • (1997) Trends Genet , vol.13 , pp. 410-414
    • Brash, D.E.1
  • 42
    • 0027969997 scopus 로고
    • Aberrations of the tumor suppressor p53 gene and p53 protein in solar keratosis in human skin
    • M Taguchi S Watanabe K Yashima 1994 Aberrations of the tumor suppressor p53 gene and p53 protein in solar keratosis in human skin J Invest Dermatol 103 500 503
    • (1994) J Invest Dermatol , vol.103 , pp. 500-503
    • Taguchi, M.1    Watanabe, S.2    Yashima, K.3
  • 43
    • 0023818793 scopus 로고
    • Malignant transformation of solar keratoses to squamous cell carcinoma
    • R Marks G Rennie TS Selwood 1988 Malignant transformation of solar keratoses to squamous cell carcinoma Lancet 1 795 797
    • (1988) Lancet , vol.1 , pp. 795-797
    • Marks, R.1    Rennie, G.2    Selwood, T.S.3
  • 44
    • 0037169935 scopus 로고    scopus 로고
    • Progression of actinic keratosis to squamous cell carcinoma of the skin correlates with deletion of the 9p21 region encoding the p16(INK4a) tumor suppressor
    • L Mortier P Marchetti E Delaporte 2002 Progression of actinic keratosis to squamous cell carcinoma of the skin correlates with deletion of the 9p21 region encoding the p16(INK4a) tumor suppressor Cancer Lett 176 205 214
    • (2002) Cancer Lett , vol.176 , pp. 205-214
    • Mortier, L.1    Marchetti, P.2    Delaporte, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.