In Saccharomyces cerevisiae an unbalanced level of tyrosine phosphorylation down-regulates the Ras/PKA pathway

International Journal of Biochemistry and Cell Biology

Volumn 38, Issue 3, 2006, Pages 444-460

  Magherini, Francesca ^a   Busti, Stefano ^b   Gamberi, Tania ^a   Sacco, Elena ^b   Raugei, Giovanni ^a   Manao, Gianpaolo ^a   Ramponi, Giampietro ^a   Modesti, Alessandra ^a   Vanoni, Marco ^b  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

Budding yeast; cAMP; Gpr1 Gpa2 pathway; Protein tyrosine phosphatase; Ras pathway; Signal transduction; Stress resistance

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; GUANOSINE TRIPHOSPHATE; PROTEIN; RAS PROTEIN; STP1 PROTEIN; UNCLASSIFIED DRUG;

ACIDIFICATION; ARTICLE; CARBON SOURCE; CATALYSIS; CELL CYCLE; CORRELATION ANALYSIS; DOWN REGULATION; ENZYME ACTIVITY; FUNGAL METABOLISM; FUNGUS GROWTH; GENETIC DATABASE; IMMUNOPRECIPITATION; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES POMBE; STRESS; YEAST;

CELL CYCLE; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOWN-REGULATION; ETHANOL; GLYCOGEN; GTP-BINDING PROTEIN ALPHA SUBUNITS; GTPASE-ACTIVATING PROTEINS; PHENOTYPE; PHOSPHORYLATION; PROTEIN-TYROSINE-PHOSPHATASE; RAS PROTEINS; RECEPTORS, G-PROTEIN-COUPLED; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SCHIZOSACCHAROMYCES POMBE PROTEINS; SIGNAL TRANSDUCTION; TYROSINE;

FUNGI; SACCHAROMYCES CEREVISIAE; SACCHAROMYCETALES; SCHIZOSACCHAROMYCES POMBE;

EID: 29244441673     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2005.10.004     Document Type: Article

References (74)

1. L. Alberghina, R.L. Rossi, L. Querin, V. Wanke, and M. Vanoni A cell sizer network involving Cln3 and Far1 controls entrance into S phase in the mitotic cycle of budding yeast J. Cell Biol. 167 2004 433 443
2. L.H. Augenlicht, and R. Baserga Changes in the G0 state of WI-38 fibroblasts at different times after confluence Exp. Cell Res. 89 1974 255 262
3. G. Berben, J. Dumont, V. Gilliquet, P.A. Bolle, and F. Hilger The YDp plasmids: A uniform set of vectors bearing versatile gene disruption cassettes for Saccharomyces cerevisiae Yeast 7 1991 475 477
4. J. Blom, S. Gammeltoft, and S. Brunak Sequence and structure-based prediction of eukaryotic protein phosphorylation sites J. Mol. Biol. 294 1999 1351 1362
5. A. Breitkreutz, and M. Tyers MAPK signaling specificity: It takes two to tango Trends Cell Biol. 12 2002 254 257
6. J.H. Camonis, M. Kalekine, B. Gondre, H. Garreau, E. Boy-Marcotte, and M. Jacquet Characterization, cloning and sequence analysis of the CDC25 gene which controls the cyclic AMP level of Saccharomyces cerevisiae EMBO J. 5 1986 375 380
7. A. Caselli, M.L. Taddei, G. Manao, G. Camici, and G. Ramponi Tyrosine-phosphorylated caveolin is a physiological substrate of the low M(r) protein-tyrosine phosphatase J. Biol. Chem. 276 2001 18849 18854
8. H. Chautard, M. Jacquet, F. Schoentgen, N. Bureaud, and H. Benedetti Tfs1p, a member of the PEBP family, inhibits the Ira2p but not the Ira1p Ras GTPase-activating protein in Saccharomyces cerevisiae Eukaryot. Cell. 3 2004 459 470
9. P. Chiarugi, P. Cirri, L. Taddei, E. Giannoni, G. Camici, and G. Manao The low M(r) protein-tyrosine phosphatase is involved in Rho-mediated cytoskeleton rearrangement after integrin and platelet-derived growth factor stimulation J. Biol. Chem. 275 2000 4640 4646
10. P. Cirri, P. Chiarugi, G. Camici, G. Manao, G. Raugei, and G. Cappugi The role of Cys12, Cys17 and Arg18 in the catalytic mechanism of low-M(r) cytosolic phosphotyrosine protein phosphatase Eur. J. Biochem. 214 1993 647 657
11. S. Colombo, P. Ma, L. Cauwenberg, J. Winderickx, M. Crauwels, and A. Teunissen Involvement of distinct G-proteins, Gpa2 and Ras, in glucose- and intracellular acidification-induced cAMP signalling in the yeast Saccharomyces cerevisiae EMBO J. 17 1998 3326 3341
12. S. Colombo, D. Ronchetti, J.M. Thevelein, J. Windedckx, and E. Martegani Activation state of the Ras2 protein and glucose-induced signaling in Saccharomyces cerevisiae J. Biol. Chem. 279 2004 46715 46722
13. P.J. Cullen, and GF. Sprague Jr. Glucose depletion causes haploid invasive growth in yeast Proc. Natl. Acad. Sci. U.S.A. 97 2000 13461 13463
14. F. Damak, E. Boy-Marcotte, D. Le-Roscouet, R. Guilbaud, and M. Jacquet SDC25, a CDC25-like gene which contains a RAS-activating domain and is a dispensable gene of Saccharomyces cerevisiae Mol. Cell. Biol. 11 1991 202 212
15. C. Ellis, M. Moran, F. McCormick, and T. Pawson Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases Nature 343 1990 377 381
16. J. Francois, M.E. Villanueva, and H.G. Hers The control of glycogen metabolism in yeast. 1. Interconversion in vivo of glycogen synthase and glycogen phosphorylase induced by glucose, a nitrogen source or uncouplers Eur. J. Biochem. 174 1998 551 559
17. J.M. Gancedo Control of pseudohyphae formation in Saccharomyces cerevisiae FEMS Microbiol. Rev. 25 2001 107 123
18. A.C. Gavin, M. Bosche, R. Krause, P. Grandi, M. Marzioch, and A. Bauer Functional organization of the yeast proteome by systematic analysis of protein complexes Nature 415 2002 141 147
19. S. Ghaemmaghami, W.K. Huh, K. Bower, R.W. Howson, A. Belle, and N. Dephoure Global analysis of protein expression in yeast Nature 425 2003 737 741
20. Mm Eur. J. Biochem. 268 2001 3275 3283
21. C.J. Gimeno, P.O. Ljungdahl, C.A. Styles, and G.R. Fink Unipolar cell divisions in the yeast S. cerevisiae lead to filamentous growth: Regulation by starvation and RAS Cell 68 1992 1077 1090
22. R. Grandori, M. Vai, M.F. Di Renzo, L. Alberghina, and L. Popolo Identification of a protein cross-reacting with anti-phosphotyrosine antibodies in yeast insoluble cytoplasmic matrices Biochem. Biophys. Res. Commun. 160 1989 887 896
23. M.C. Gustin, J. Albertyn, M. Alexander, and K. Davenport MAP kinase pathways in the yeast Saccharomyces cerevisiae Microbiol. Mol. Biol. Rev. 62 1998 1264 1300 Review
24. T. Hunter, and G.D. Plowman The protein kinases of budding yeast: Six score and more Trends Biochem. Sci. 22 1997 18 22 Review
25. H. Iida, and I. Yahara Specific early G1 blocks accompanied with stringent response in Saccharomyces cerevisiae lead to growth arrest in resting state similar to the G0 of higher eukaryotes J. Cell Biol. 98 1984 1185 1192
26. Y. Jiang, C. Davis, and J.R. Broach Efficient transition to growth on fermentable carbon sources in Saccharomyces cerevisiae requires signaling through the Ras pathway EMBO J. 17 1998 6942 6951
27. C. Kanik-Ennulat, E. Montalvo, and N. Neff Sodium orthovanadate-resistant mutants of Saccharomyces cerevisiae show defects in Golgi-mediated protein glycosylation, sporulation and detergent resistance Genetics 140 1995 933 943
28. S.M. Keyse Protein phosphatases and the regulation of mitogen activated protein kinase signalling Curr. Opin. Cell Biol. 12 2000 186 192
29. L. Kraakman, K. Lemaire, P. Ma, A.W.R.H. Teunissen, M.C.V. Donaton, and P. Van Dijck A Saccharomyces cerevisiae G-protein coupled receptor, Gpr1, is specifically required for glucose activation of the cAMP pathway during the transition to growth on glucose Mol. Microbiol. 32 1999 1002 1012
30. H. Liu, C.A. Styles, and G.R. Fink Elements of the yeast pheromone response pathway required for filamentous growth of diploids Science 262 1993 1741 1744
31. M.C. Lorenz, and J. Heitman Yeast pseudohyphal growth is regulated by Gpa2, a G protein alpha homolog EMBO J. 16 1997 7008 7018
32. P. Ma, S. Wera, P. Van Dijck, and J.M. Thevelein The PDE1-encoded low-affinity phosphodiesterase in yeast Saccharomyces cerevisiae has a specific function in controlling agonist-induced cAMP signalling Mol. Biol. Cell 10 1999 91 104
33. F. Magherini, T. Gamberi, P. Paoli, M. Marchetta, M. Biagini, and G. Raugei Biochem. Biophys. Res. Commun. 20 2004 424 431
34. M. Marchetta, T. Gamberi, S. Sarno, F. Magherini, G. Raugei, and G. Camici Expression of the Stp1 LMW-PTP and inhibition of protein CK2 display a cooperative effect on immunophilin Fpr3 tyrosine phosphorylation and Saccharomyces cerevisiae growth Cell. Mol. Life Sci. 61 2004 1176 1184
35. C.P. Mattison, and I.M. Ota Two protein tyrosine phosphatases, Ptp2 and Ptp3, modulate the subcellular localization of the Hog1 MAP kinase in yeast Genes Dev. 15 2000 1229 1235
36. C.P. Mattison, S.S. Spencer, K.A. Kresge, J. Lee, and I.M. Ota Differential regulation of the cell wall integrity mitogen-activated protein kinase pathway in budding yeast by the protein tyrosine phosphatases Ptp2 and Ptp3 Mol. Cell. Biol. 19 1999 7651 7660
37. A. Modesti, L. Bini, L. Carraresi, F. Magherini, S. Liberatori, and V. Pallini Expression of the small tyrosine phosphatase (Stp1) in Saccharomyces cerevisiae: A study on protein tyrosine phosphorylation Electrophoresis 22 2001 576 585
38. A. Modesti, P. Cirri, G. Raugei, L. Carraresi, F. Magherini, and G. Manao Expression, purification and kinetic behaviour of fission yeast low M(r) protein-tyrosine phosphatase FEBS Lett. 375 1995 235 238
39. C.J. Molloy, D.P. Bottaro, T.P. Fleming, M.S. Marshall, J.B. Gibbs, and S.A. Aaronson PDGF induction of tyrosine phosphorylation of GTPase activating protein Nature 342 1989 711 714
40. O. Mondesert, S. Moreno, and P. Russel Low molecular weight protein-tyrosine phosphatases are highly conserved between fission yeast and man J. Biol. Chem. 269 1994 27996 27999
41. E. Moskivna, C. Schuller, C.T.C. Mauer, W.H. Mager, and H. Ruis A search in the genome of Saccharomyces cerevisiae for genes regulated via stress response elements Yeast 14 1998 1041 1050
42. G. Müller, N. Rouveyre, A. Crecelius, and W. Bandlow Insulin signaling in the yeast Saccharomyces cerevisiae. 1. Stimulation of glucose metabolism and Snf1 kinase by human insulin Biochemistry 37 1998 8683 8695
43. J. Nikawa, P. Sass, and M. Wigler Cloning and characterization of the low-affinity cyclic AMP phosphodiesterase gene of Saccharomyces cerevisiae Mol. Cell. Biol. 7 1987 3629 3636
44. K. Ostanin, C. Pokalsky, S. Wang, and R.L. Van Etten Characterization of a Saccharomyces cerevisiae gene encoding the low molecular weight protein tyrosine phosphahatase J. Biol. Chem. 270 1995 18491 18499
45. S.P. Palecek, A.S. Parikh, and S.J. Kron Sensing, signalling and integrating physical processes during Saccharomyces cerevisiae invasive and filamentous growth Microbiology 148 2002 893 907
46. X. Pan, T. Harashima, and J. Heitman Transduction cascades regulating pseudohyphal differentiation of Saccharomyces cerevisiae Curr. Opin. Microbiol. 3 2000 567 572
47. S. Park, and R. Jove Tyrosine phosphorylation of Ras GTPase-activating protein stabilizes its association with p62 at membranes of v-Src transformed cells J. Biol. Chem. 268 1993 25728 25734
48. G. Rigaut, A. Shevchenko, B. Rutz, M. Wilm, M. Mann, and B. Seraphin A generic protein purification method for protein complex characterization and proteome exploration Nat. Biotechnol. 17 1999 1030 1032
49. R.L. Roberts, and G.R. Fink Elements of a single MAP kinase cascade in Saccharomyces cerevisiae mediate two developmental programs in the same cell type: Mating and invasive growth Genes Dev. 8 1994 2974 2985
50. L.C. Robinson, J.B. Gibbs, M.S. Marshall, I.S. Sigal, and K. Tatchell CDC25: A component of the RAS-adenylate cyclase pathway in Saccharomyces cerevisiae Science 235 1987 1218 1221
51. F. Rolland, J. Winderickx, and J.M. Thevelein Glucose-sensing and -signalling mechanisms in yeast FEMS Yeast Res. 2 2002 183 201
52. S. Rudoni, S. Colombo, P. Coccetti, and E. Martegani Role of guanine nucleotides in the regulation of the Ras/cAMP pathway in Saccharomyces cerevisiae Biochem. Biophys. Acta 1538 2001 181 189
53. H. Ruis, and C. Schuller Stress signalling in yeast Bioessays 17 1995 959 965
54. S. Rupp, E. Summers, H.J. Lo, H. Madhani, and G. Fink MAP kinase and cAMP filamentation signaling pathways converge on the unusually large promoter of the yeast FLO11 gene EMBO J. 18 1999 1257 1269
55. P. Russell, S. Moreno, and S.I. Reed Conservation of mitotic controls in fission and budding yeasts Cell 57 1989 295 303
56. N. Sakumoto, I. Matsuoka, Y. Mukai, N. Ogawa, Y. Kaneko, and S. Harashima A series of double disruptants for protein phosphatase genes in Saccharomyces cerevisiae and their phenotypic analysis Yeast 19 2002 587 599
57. P. Sass, J. Field, J. Nikawa, T. Toda, and M. Wigler Cloning and characterization of the high-affinity cAMP phosphodiesterase of Saccharomyces cerevisiae Proc. Natl. Acad. Sci. 83 1986 9303 9307
58. G. Schieven, J. Thorner, and G.S. Martin Protein-tyrosine kinase activity in Saccharomyces cerevisiae Science 231 1986 390 393
59. A. Smith, M.P. Ward, and S. Garrett Yeast PKA represses Msn2p/Msn4p-dependent gene expression to regulate growth, stress response and glycogen accumulation EMBO J. 11 1998 3556 3564
60. M.L. Taddei, P. Chiarugi, P. Cirri, D. Talini, G. Camici, and G. Manao LMW-PTP exerts a differential regulation on PDGF- and insulin-mediated signalling Biochem. Biophys. Res. Commun. 13 2000 564 569
61. K. Tanaka, M. Nakafuku, T. Satoh, M.S. Marshall, J.B. Gibbs, and K. Matsumoto S. cerevisiae genes IRA1 and IRA2 encode proteins that may be functionally equivalent to mammalian ras GTPase activating protein Cell 60 1990 803 807
62. J.M. Thevelein, and J.H. deWinde Novel sensing mechanisms and targets for the cAMP-protein kinase A pathway in the yeast Saccharomyces cerevisiae Mol. Microbiol. 33 1999 904 918
63. B.J. Thomas, and R. Rothstein Elevated recombination rates in transcriptionally active DNA Cell 56 1989 619 630
64. T. Toda, I. Uno, T. Ishikawa, S. Powers, T. Kataoka, and D. Broek In yeast, Ras proteins are controlling elements of adenylate cyclase Cell 40 1985 27 36
65. P. Van der Geer, T. Hunter, and R. Lindberg Receptor protein-tyrosine kinases and their signal transduction pathways Annu. Rev. Cell. Biol. 10 1994 251 337
66. J.B. Van der Plaat Cyclic 3′,5′-adenosine monophosphate stimulates trehalose degradation in baker's yeast Biochem. Biophys. Res. Commun. 56 1974 580 587
67. M. Vanoni, and S.P. Johnson Phosphorylation of ribosomal protein S10 is dispensable for initiation of DNA replication and bud emergence in Saccharomyces cerevisiae Eur. J. Cell Biol. 55 1991 179 182
68. M. Vanoni, M. Vai, L. Popolo, and L. Alberghina Structural heterogeneity in populations of the budding yeast Saccharomyces cerevisiae J. Bacteriol. 156 1983 1282 1291
69. J.C. Varela, U.M. Praekelt, P.A. Meacock, R.J. Planta, and W.H. Mager The Saccharomyces cerevisiae HSP12 gene is activated by the high-osmolarity glycerol pathway and negatively regulated by protein kinase A Mol. Cell. Biol. 15 1995 6232 6245
70. K.M. Walton, and J.E. Dixon Protein tyrosine phosphatases Annu. Rev. Biochem. 62 1993 101 120
71. V. Wanke, A. Accorsi, D. Porro, F. Esposito, T. Russo, and M. Vanoni In budding yeast, reactive oxygen species induce both RAS-dependent and independent cell cycle-specific effects Mol. Microbiol. 32 1999 753 764
72. α subunit and functions in a Ras-independent pathway EMBO J. 17 1998 1996 2007
73. X.L. Zhan, R.J. Deschenes, and K.L. Guan Differential regulation of FUS3 MAP kinase by tyrosine-specific phosphatases PTP2/PTP3 and dual-specificity phosphatase MSG5 in Saccharomyces cerevisiae Genes Dev. 11 1997 1690 1702
74. H. Zhu, J.F. Klemic, S. Chang, P. Bertone, A. Casamayor, and K.G. Klemic Analysis of yeast protein kinase using protein chips Nat. Genet. 26 2000 283 289