A novel imidazole nucleoside containing a diaminodihydro-S-triazine as a substituent: Inhibitory activity against the West Nile virus NTPase/helicase

Nucleosides, Nucleotides and Nucleic Acids

Volumn 24, Issue 10-12, 2005, Pages 1775-1788

  Ujjinamatada, Ravi K ^a   Agasimundin, Yankanagouda S ^a   Zhang, Peng ^a   Hosmane, Ramachandra S ^a   Schuessler, Roman ^b   Borowski, Peter ^b   Kalicharran, Kishna ^c   Fattom, Ali ^c  

^a UNIVERSITY OF MARYLAND BALTIMORE COUNTY   (United States)

^b BERNHARD NOCHT INSTITUTE FOR TROPICAL MEDICINE   (Germany)

^c Nabi Biopharmaceuticals   (United States)

Author keywords

Imidazole; Inhibition; Nucleoside; Rearrangement; Ring expanded nucleoside; s Triazine; West Nile Virus

Indexed keywords

1 (2' DEOXY BETA DEXTRO ERYTHROPENTOFURANOSYL) 5 (2,4 DIAMINO 3,6 DIHYDRO 1,3,5 TRIAZIN 6 YL)IMIDAZOLE 4 CARBOXAMIDE; ANTIVIRUS AGENT; HELICASE; IMIDAZOLE; TRIAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; DRUG SYNTHESIS; ENZYME ACTIVATION; ENZYME INHIBITION; POLYMERIZATION; STRUCTURE ANALYSIS; SUBSTITUTION REACTION; WEST NILE FLAVIVIRUS;

ANTIVIRAL AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; GUANOSINE; IMIDAZOLES; NUCLEOSIDE-TRIPHOSPHATASE; RNA HELICASES; VIRAL PROTEINS; WEST NILE VIRUS;

HUMAN ECHOVIRUS 1; WEST NILE VIRUS;

EID: 29244435042     PISSN: 15257770     EISSN: 15322335     Source Type: Journal    
DOI: 10.1080/15257770500267063     Document Type: Article

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