Evidence of the monoclonal composition of human endometrial epithelial glands and mosaic pattern of clonal distribution in luminal epithelium

American Journal of Pathology

Volumn 163, Issue 1, 2003, Pages 295-301

  Tanaka, Masaaki ^c   Kyo, Satoru ^b   Kanaya, Taro ^c   Yatabe, Noriyuki ^c   Nakamura, Mitsuhiro ^c   Maida, Yoshiko ^c   Okabe, Masaru ^a   Inoue, Masaki ^c  

^a OSAKA UNIVERSITY   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; GREEN FLUORESCENT PROTEIN;

ARTICLE; CARCINOGENESIS; CELL TYPE; CLONAL VARIATION; ENDOMETRIUM; ENDOMETRIUM CANCER; EPITHELIUM CELL; FEMALE; FLUORESCENCE MICROSCOPY; GENE LOSS; GENETIC HETEROGENEITY; HUMAN; HUMAN TISSUE; MOSAICISM; NIDATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RECEPTOR GENE; STEM CELL; TISSUE REGENERATION; X CHROMOSOME INACTIVATION;

EID: 0038306893     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)63653-X     Document Type: Article

References (24)

1. Thomas GA, Williams D, Williams ED: The demonstration of tissue clonality by X-linked enzyme histochemistry. J Pathol 1988, 155:101-108
2. Griffiths DF, Davies SJ, Williams D, Williams GT, Williams ED: Demonstration of somatic mutation and colonic crypt clonality by X-linked enzyme histochemistry. Nature 1988, 333:461-463
3. Lyon MF: Sex chromatin and gene action in the mammalian X-chromosome. Am J Hum Genet 1962, 14:135-148
4. Fialkow PJ, Gartler SM, Yoshida A: Clonal origin of chronic myelocytic leukemia in Mab. Proc Natl Acad Sci USA 1967, 58:1467-1471
5. Wolf SF, Migeon BR: Studies of X chromosome DNA methylation in normal human cells. Nature 1982, 295:667-671
6. Gartler SM, Riggs AD: Mammalian X-chromosome inactivation. Ann Rev Genet 1983, 17:155-190
7. Marshal RD, Lester SC, Sklar J: Clonal analysis by study of X chromosome inactivation in formalin-fixed paraffin-embedded tissue. Cancer Res 1993, 53:4676-4679
8. Enomoto T, Fujita M, Inoue M, Tanizawa O, Nomura T, Shroyer KR: Analysis of clonality by amplification of short tandem repeats. Carcinomas of the female reproductive tract. Diagn Mol Pathol 1994, 3:292-297
9. Mutter GL, Chaponot ML, Fletcher JA: A polymerase chain reaction assay for non-random X chromosome inactivation identifies monoclonal endometrial cancers and precancers. Am J Pathol 1995, 146:501-508
10. Jovanovic AS, Boynton KA, Mutter GL: Uteri of women with endometrial carcinoma contain a histopathological spectrum of monoclonal putative precancers, some with microsatellite instability. Cancer Res 1996, 56:1917-1921
11. Esteller M, Garcia A, Martinez-Palones JM, Xercavins J, Reventos J: Detection of clonality and genetic alterations in endometrial pipelle biopsy and its surgical specimen counterpart. Lab Invest 1997, 76: 109-116
12. Tanaka M, Kyo S, Takakura M, Kanaya T, Sagawa T, Yamashita K, Okada Y, Hiyama E, Inoue M: Expression of telomerase activity in human endometrium is localized to epithelial glandular cells and regulated in a menstrual phase-dependent manner correlated with cell proliferation Am J Pathol 1998, 153:1985-1991
13. Allen RC, Zoghbi HY, Moseley AB, Rosenblatt HM, Belmont JW: Methylation of Hpall and Hhal sites near the polymorphic CAG repeat in the human androgen-receptor gene correlates with X chromosome inactivation. Am J Hum Genet 1992, 51:1229-1239
14. Okabe M, Ikawa M, Kominami K, Nakanishi T, Nishimune Y: 'Green mice' as a source of ubiquitous green cells. FEBS Lett 1997, 407: 313-319
15. Hadjantonakis AK, Gertsenstein M, Ikawa M, Okabe M, Nagy A: Non-invasive sexing of preimplantation stage mammalian embryos. Nat Genet 1998, 19:220-222
16. Hadjantonakis AK, Cox LL, Tam PP, Nagy A: An X-linked GFP transgene reveals unexpected paternal X-chromosome activity in trophoblastic giant cells of the mouse placenta. Genesis 2001, 29:133-140
17. Prianishnikov VA: On the concept of stem cell and a model of functional-morphological structure of the endometrium. Contraception 1978, 18:213-223
18. Williams ED, Lowes AP, Williams D, Williams GT: A stem cell niche theory of intestinal crypt maintenance based on a study of somatic mutation in colonic mucosa Am J Pathol 1992, 141:773-776
19. Kim KM, Shibata D: Methylation reveals a niche: stem cell succession in human colon crypts. Oncogene 2002, 21:5441-5449
20. Lengauer C, Kinzler KW, Vogelstein B: Genetic instabilities in human cancers. Nature 1998, 396:643-649
21. Yatabe Y, Tavare S, Shibata D: Investigating stem cells in human colon by using methylation patterns. Proc Natl Acad Sci USA 2001, 98:10839-10844
22. Pack SD, Tanigami A, Ledbetter DH, Sato T, Fukuda MN: Assignment of trophoblast/endometrial epithelium cell adhesion molecule trophinin gene TRO to human chromosome bands Xp11.22 - >p11.21 by in situ hybridization. Cytogenet Cell Genet 1997, 79:123-124
23. Fukuda MN, Sato T, Nakayama J, Klier G, Mikami M, Aoki D, Nozawa S: Trophinin and tastin, a novel cell adhesion molecule complex with potential involvement in embryo implantation. Genes Dev 1995, 9:1199-1210
24. Mutter GL, Ince TA, Baak JP, Kust GA, Zhou XP, Eng C: Molecular identification of latent precancers in histologically normal endometrium. Cancer Res 2001, 61:4311-4314