메뉴 건너뛰기




Volumn 9, Issue 4, 2005, Pages 313-318

Structural and biochemical properties of fibroblast growth factor 23

Author keywords

Biochemistry; ELISA; Fibroblast growth factor 19; Fibroblast growth factor 23; Structure

Indexed keywords

FIBROBLAST GROWTH FACTOR 23;

EID: 29144500469     PISSN: 17449979     EISSN: 17449987     Source Type: Journal    
DOI: 10.1111/j.1744-9987.2005.00288.x     Document Type: Article
Times cited : (42)

References (38)
  • 1
    • 0033763097 scopus 로고    scopus 로고
    • Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23
    • The ADHR Consortium. Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23. Nat Genet 2000;26:345-8.
    • (2000) Nat Genet , vol.26 , pp. 345-348
  • 2
    • 0034703619 scopus 로고    scopus 로고
    • Identification of a novel fibroblast growth factor, FGF23, preferentially expressed in the ventrolateral thalamic nucleus of the brain
    • Yamashita T, Yoshioka M, Itoh N. Identification of a novel fibroblast growth factor, FGF23, preferentially expressed in the ventrolateral thalamic nucleus of the brain. Biochem Biophys Res Commun 2000;277:494-8.
    • (2000) Biochem Biophys Res Commun , vol.277 , pp. 494-498
    • Yamashita, T.1    Yoshioka, M.2    Itoh, N.3
  • 3
    • 4744372082 scopus 로고    scopus 로고
    • Evolution of the Fgf and Fgfr gene families
    • Itoh N, Ornitz DM. Evolution of the Fgf and Fgfr gene families. Trends Genet 2004;20:563-9.
    • (2004) Trends Genet , vol.20 , pp. 563-569
    • Itoh, N.1    Ornitz, D.M.2
  • 4
    • 1642494893 scopus 로고    scopus 로고
    • The crystal structure of fibroblast growth factor (FGF) 19 reveals novel feaures of the FGF family and offers a structural basis for its unusual receptor affinity
    • Harmer NJ, Pellegrini L, Chirgadze D et al. The crystal structure of fibroblast growth factor (FGF) 19 reveals novel feaures of the FGF family and offers a structural basis for its unusual receptor affinity. Biochemistry 2004;43:629-40.
    • (2004) Biochemistry , vol.43 , pp. 629-640
    • Harmer, N.J.1    Pellegrini, L.2    Chirgadze, D.3
  • 5
    • 14344279878 scopus 로고    scopus 로고
    • Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia
    • Shimada T, Mizutani S, Muto T et al. Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia. Proc Natl Acad Sci USA 2001;98:6500-5.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6500-6505
    • Shimada, T.1    Mizutani, S.2    Muto, T.3
  • 7
    • 18444375871 scopus 로고    scopus 로고
    • Mutant FGF23 responsible for autosomal dominant hypophosphatemic rickets is resistant to proteolytic cleavage and causes hypophosphatemia in vivo
    • Shimada T, Muto T, Urakawa I et al. Mutant FGF23 responsible for autosomal dominant hypophosphatemic rickets is resistant to proteolytic cleavage and causes hypophosphatemia in vivo. Endocrinology 2001;143:3179-82.
    • (2001) Endocrinology , vol.143 , pp. 3179-3182
    • Shimada, T.1    Muto, T.2    Urakawa, I.3
  • 8
    • 18744371012 scopus 로고    scopus 로고
    • Increased circulatory level of biologically active full-length FGF23 in patients with hypophosphatemic rickets/osteomalacia
    • Yamazaki Y, Okazaki R, Shibata M et al. Increased circulatory level of biologically active full-length FGF23 in patients with hypophosphatemic rickets/osteomalacia. J Clin Endocrinol Metab 2002;87:4957-60.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 4957-4960
    • Yamazaki, Y.1    Okazaki, R.2    Shibata, M.3
  • 9
    • 20244368616 scopus 로고    scopus 로고
    • Fibroblast growth factor 23 in oncogenic osteomalacia and X-linked hypophosphatemia
    • Jonsson KB, Zahradnik R, Larsson T et al. Fibroblast growth factor 23 in oncogenic osteomalacia and X-linked hypophosphatemia. N Engl J Med 2003;348:1656-63.
    • (2003) N Engl J Med , vol.348 , pp. 1656-1663
    • Jonsson, K.B.1    Zahradnik, R.2    Larsson, T.3
  • 10
    • 0141525564 scopus 로고    scopus 로고
    • Serum FGF23 levels in normal and disordered phosphorus homeostasis
    • Weber TJ, Liu S, Indridason OS et al. Serum FGF23 levels in normal and disordered phosphorus homeostasis. J Bone Miner Res 2003;18:1227-34.
    • (2003) J Bone Miner Res , vol.18 , pp. 1227-1234
    • Weber, T.J.1    Liu, S.2    Indridason, O.S.3
  • 12
    • 0013118819 scopus 로고    scopus 로고
    • The autosomal dominant hypophosphatemic rickets R176Q mutation in fibroblast growth factor 23 resists proteolytic cleavage and enhances in vivo biological potency
    • Bai XY, Miao D, Goltzman D et al. The autosomal dominant hypophosphatemic rickets R176Q mutation in fibroblast growth factor 23 resists proteolytic cleavage and enhances in vivo biological potency. J Biol Chem 2003;278:9843-9.
    • (2003) J Biol Chem , vol.278 , pp. 9843-9849
    • Bai, X.Y.1    Miao, D.2    Goltzman, D.3
  • 13
    • 9144248333 scopus 로고    scopus 로고
    • FGF23 transgenic mice demonstrate hypophosphatemic rickets with reduced expression of sodium phosphate cotransporter type IIa
    • Shimada T, Urakawa I, Yamazaki Y et al. FGF23 transgenic mice demonstrate hypophosphatemic rickets with reduced expression of sodium phosphate cotransporter type IIa. Biochem Biophys Res Commun 2004;314:409-14.
    • (2004) Biochem Biophys Res Commun , vol.314 , pp. 409-414
    • Shimada, T.1    Urakawa, I.2    Yamazaki, Y.3
  • 14
    • 3042634460 scopus 로고    scopus 로고
    • Transgenic mice expressing fibroblast growth factor 23 under the control of the alpha 1(I) collagen promotor exhibit growth retardation, osteomalacia, and disturbed phosphate homeostasis
    • Larsson T, Marsell R, Shipani E et al. Transgenic mice expressing fibroblast growth factor 23 under the control of the alpha 1(I) collagen promotor exhibit growth retardation, osteomalacia, and disturbed phosphate homeostasis. Endocrinology 2004;145:3087-94.
    • (2004) Endocrinology , vol.145 , pp. 3087-3094
    • Larsson, T.1    Marsell, R.2    Shipani, E.3
  • 15
    • 9244240970 scopus 로고    scopus 로고
    • Transgenic mice overexpressing human fibroblast growth factor 23 (R176Q) delineate a putative role for parathyroid hormone in renal phosphate wasting disorders
    • Bai XY, Miao D, Li J et al. Transgenic mice overexpressing human fibroblast growth factor 23 (R176Q) delineate a putative role for parathyroid hormone in renal phosphate wasting disorders. Endocrinology 2004;145:5269-79.
    • (2004) Endocrinology , vol.145 , pp. 5269-5279
    • Bai, X.Y.1    Miao, D.2    Li, J.3
  • 16
    • 1642416884 scopus 로고    scopus 로고
    • Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism
    • Shimada T, Kakitani M, Yamazaki Y et al. Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism. J Clin Invest 2004;13:561-8.
    • (2004) J Clin Invest , vol.13 , pp. 561-568
    • Shimada, T.1    Kakitani, M.2    Yamazaki, Y.3
  • 17
    • 9644303231 scopus 로고    scopus 로고
    • Homozygous ablation of fibroblast growth factor-23 results in hyperphosphatemia and impaired skeletogenesis, and reverseshypophosphatemia in Phex-deficient mice
    • Sitara D, Razzaque MS, Hesse M et al. Homozygous ablation of fibroblast growth factor-23 results in hyperphosphatemia and impaired skeletogenesis, and reverseshypophosphatemia in Phex-deficient mice. Matrix Biol 2004;23:421-32.
    • (2004) Matrix Biol , vol.23 , pp. 421-432
    • Sitara, D.1    Razzaque, M.S.2    Hesse, M.3
  • 18
    • 2142746439 scopus 로고    scopus 로고
    • FGF23 is a potent regulator of the vitamin D metabolism and phosphate homeostasis
    • Shimada T, Hasegawa H, Yamazaki Y et al. FGF23 is a potent regulator of the vitamin D metabolism and phosphate homeostasis. J Bone Miner Res 2004;19:429-35.
    • (2004) J Bone Miner Res , vol.19 , pp. 429-435
    • Shimada, T.1    Hasegawa, H.2    Yamazaki, Y.3
  • 19
    • 0042830485 scopus 로고    scopus 로고
    • Effect of hydrolysis-resistant FGF23-R179Q on dietary phosphate regulation of the renal type-II Na/Pi transporter
    • Segawa H, Kawakami E, Kaneko I et al. Effect of hydrolysis-resistant FGF23-R179Q on dietary phosphate regulation of the renal type-II Na/Pi transporter. Pflugers Arch 2003;446:585-92.
    • (2003) Pflugers Arch , vol.446 , pp. 585-592
    • Segawa, H.1    Kawakami, E.2    Kaneko, I.3
  • 20
    • 0347362503 scopus 로고    scopus 로고
    • The phosphatonin pathway: New insights in phosphate homeostasis
    • Schiavi SC, Kumar R. The phosphatonin pathway: new insights in phosphate homeostasis. Kidney Int 2004;65:1-14.
    • (2004) Kidney Int , vol.65 , pp. 1-14
    • Schiavi, S.C.1    Kumar, R.2
  • 21
    • 2542505481 scopus 로고    scopus 로고
    • Fibroblast growth factor 19 increases metabolic rate and reverses dietary and leptin-deficient diabetes
    • Fu L, John LM, Adams SH et al. Fibroblast growth factor 19 increases metabolic rate and reverses dietary and leptin-deficient diabetes. Endocrinology 2004;145:2594-603.
    • (2004) Endocrinology , vol.145 , pp. 2594-2603
    • Fu, L.1    John, L.M.2    Adams, S.H.3
  • 22
    • 85047691059 scopus 로고    scopus 로고
    • FGF23 in fibrous dysplasia of bone and its relationship to renal phosphate wasting
    • Riminucci M, Collins MT, Fedarko NS et al. FGF23 in fibrous dysplasia of bone and its relationship to renal phosphate wasting. J Clin Invest 2003;112:683-92.
    • (2003) J Clin Invest , vol.112 , pp. 683-692
    • Riminucci, M.1    Collins, M.T.2    Fedarko, N.S.3
  • 23
    • 0344945402 scopus 로고    scopus 로고
    • Circulating concentration of FGF23 increases as renal function declines in patients with chronic kidney disease, but does not change in response to variation in phosphate intake in healthy volunteers
    • Larsson T, Nisbeth U, Ljunggren O et al. Circulating concentration of FGF23 increases as renal function declines in patients with chronic kidney disease, but does not change in response to variation in phosphate intake in healthy volunteers. Kidney Int 2003;64:2272-9.
    • (2003) Kidney Int , vol.64 , pp. 2272-2279
    • Larsson, T.1    Nisbeth, U.2    Ljunggren, O.3
  • 24
    • 3242661165 scopus 로고    scopus 로고
    • Possible involvement of circulating fibroblast growth factor 23 in the development of secondary hyperparathyroidism associated with renal insufficiency
    • Shigematsu T, Kazama JJ, Yamashita T et al. Possible involvement of circulating fibroblast growth factor 23 in the development of secondary hyperparathyroidism associated with renal insufficiency. Am J Kidney Dis 2004;44:250-6.
    • (2004) Am J Kidney Dis , vol.44 , pp. 250-256
    • Shigematsu, T.1    Kazama, J.J.2    Yamashita, T.3
  • 25
    • 2342481131 scopus 로고    scopus 로고
    • FGF23 in patients with end-stage renal disease on hemodialysis
    • Imanishi Y, Inaba M, Nakatsuka K et al. FGF23 in patients with end-stage renal disease on hemodialysis. Kidney Int 2004;65:1943-6.
    • (2004) Kidney Int , vol.65 , pp. 1943-1946
    • Imanishi, Y.1    Inaba, M.2    Nakatsuka, K.3
  • 26
    • 4444308167 scopus 로고    scopus 로고
    • Total parathyroidectomy reduces elevated circulating fibroblast growth factor 23 in advanced secondary hyperparathyroidism
    • Sato T, Tominaga Y, Ueki T et al. Total parathyroidectomy reduces elevated circulating fibroblast growth factor 23 in advanced secondary hyperparathyroidism. Am J Kidney Dis 2004;44:481-7.
    • (2004) Am J Kidney Dis , vol.44 , pp. 481-487
    • Sato, T.1    Tominaga, Y.2    Ueki, T.3
  • 27
    • 0242691757 scopus 로고    scopus 로고
    • Elevated circulatory and expression level of fibroblast growth factor (FGF)-23 in hypophosphatemic mice
    • Yamazaki Y. Elevated circulatory and expression level of fibroblast growth factor (FGF)-23 in hypophosphatemic mice. (Abstract) Bone 2003;32:S88.
    • (2003) Bone , vol.32
    • Yamazaki, Y.1
  • 28
    • 4243405268 scopus 로고    scopus 로고
    • Involvement of FGF-23 in abnormal vitamin D and mineral metabolism associated with renal insufficiency
    • Yamashita T. Involvement of FGF-23 in abnormal vitamin D and mineral metabolism associated with renal insufficiency (Abstract) J Am Soc Nephrol 2002;13:577A.
    • (2002) J Am Soc Nephrol , vol.13
    • Yamashita, T.1
  • 29
    • 15044348879 scopus 로고    scopus 로고
    • Pretreatment serum FGF-23 levels predict the efficacy of calcitriol therapy in dialysis patients with secondary hyperparathyroidism
    • Kazama JJ Pretreatment serum FGF-23 levels predict the efficacy of calcitriol therapy in dialysis patients with secondary hyperparathyroidism (Abstract) J Am Soc Nephrol 2004;15:282A.
    • (2004) J Am Soc Nephrol , vol.15
    • Kazama, J.J.1
  • 30
    • 4043052503 scopus 로고    scopus 로고
    • Venous sampling for fibroblast growth factor-23 confirms preoperative diagnosis of tumor-induced osteomalacia
    • Takeuchi Y, Suzuki H, Ogura S et al. Venous sampling for fibroblast growth factor-23 confirms preoperative diagnosis of tumor-induced osteomalacia. J Clin Endocrinol Metab 2004;89:3979-82.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 3979-3982
    • Takeuchi, Y.1    Suzuki, H.2    Ogura, S.3
  • 31
    • 13544270218 scopus 로고    scopus 로고
    • An FGF23 missense mutation causes familial tumoral calcinosis with hyperphosphatemia
    • Benet-Pages A, Orlik P, Strom TM, Lorenz-Depiereux B. An FGF23 missense mutation causes familial tumoral calcinosis with hyperphosphatemia. Hum Mol Genet 2005;14:385-90.
    • (2005) Hum Mol Genet , vol.14 , pp. 385-390
    • Benet-Pages, A.1    Orlik, P.2    Strom, T.M.3    Lorenz-Depiereux, B.4
  • 32
    • 13544275944 scopus 로고    scopus 로고
    • A mutation in FGF-23 gene enhances the processing of FGF-23 protein and causes tumoral calcinosis
    • Araya K. A mutation in FGF-23 gene enhances the processing of FGF-23 protein and causes tumoral calcinosis (Abstract) J Bone Miner Res 2004;19:S41.
    • (2004) J Bone Miner Res , vol.19
    • Araya, K.1
  • 33
    • 29144463725 scopus 로고    scopus 로고
    • Hyperostosis-hyperphosphatemia syndrome caused by mutations in GALNT3 and associated with augmented processing of FGF-23
    • Frishberg Y. Hyperostosis-hyperphosphatemia syndrome caused by mutations in GALNT3 and associated with augmented processing of FGF-23 (Abstract) J Am Soc Nephrol 2004;15:269A.
    • (2004) J Am Soc Nephrol , vol.15
    • Frishberg, Y.1
  • 34
    • 15944376583 scopus 로고    scopus 로고
    • Fibroblast growth factor-23 relationship to dietary phosphate and renal phosphate handling in healthy young men
    • Ferrari SL, Bonjour JP, Rizzoli R. Fibroblast growth factor-23 relationship to dietary phosphate and renal phosphate handling in healthy young men. J Clin Endocrinol Metab 2005;90:1519-24.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 1519-1524
    • Ferrari, S.L.1    Bonjour, J.P.2    Rizzoli, R.3
  • 35
    • 19944433609 scopus 로고    scopus 로고
    • Circulating FGF-23 is regulated by 1α,25-dihydroxyvitamin D3 and phosphorus in vivo
    • Saito H, Maeda A, Ohtomo SI et al. Circulating FGF-23 is regulated by 1α,25-dihydroxyvitamin D3 and phosphorus in vivo. J Biol Chem 2005;280:2543-9.
    • (2005) J Biol Chem , vol.280 , pp. 2543-2549
    • Saito, H.1    Maeda, A.2    Ohtomo, S.I.3
  • 36
    • 9644290893 scopus 로고    scopus 로고
    • Fibroblast growth factor 23, parathyroid hormone, and 1alpha,25-dihydroxyvitamin D in surgically treated primary hyperparathyroidism
    • Tebben PJ, Singh RJ, Clarke BL et al. Fibroblast growth factor 23, parathyroid hormone, and 1alpha,25-dihydroxyvitamin D in surgically treated primary hyperparathyroidism. Mayo Clin Proc. 2004;79:1508-13
    • (2004) Mayo Clin Proc. , vol.79 , pp. 1508-1513
    • Tebben, P.J.1    Singh, R.J.2    Clarke, B.L.3
  • 37
    • 0037972518 scopus 로고    scopus 로고
    • Fibroblast growth factor 23 concentrations in humoral hypercalcemia of malignancy and hyperparathyroidism
    • Singh RJ, Kumar R. Fibroblast growth factor 23 concentrations in humoral hypercalcemia of malignancy and hyperparathyroidism. Mayo Clin Proc 2003;78:826-9.
    • (2003) Mayo Clin Proc , vol.78 , pp. 826-829
    • Singh, R.J.1    Kumar, R.2
  • 38
    • 4344649922 scopus 로고    scopus 로고
    • Fibroblast growth factor (FGF) -23 in patients with primary hyperparathyroidism
    • Yamashita H, Yamashita T, Miyamoto M et al. Fibroblast growth factor (FGF) -23 in patients with primary hyperparathyroidism. Eur J Endocrinol 2004;151:55-60.
    • (2004) Eur J Endocrinol , vol.151 , pp. 55-60
    • Yamashita, H.1    Yamashita, T.2    Miyamoto, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.