Superior virulence of Mycobacterium bovis over Mycobacterium tuberculosis (Mtb) for Mtb-resistant and Mtb-susceptible mice is manifest as an ability to cause extrapulmonary disease

Tuberculosis

Volumn 86, Issue 1, 2006, Pages 20-27

  Medina, Eva ^a,b   Ryan, Lynn ^a   LaCourse, Ronald ^a   North, Robert J ^a  

^a TRUDEAU INSTITUTE   (United States)

^b HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

Genetic resistance; Histopathology; Host survival; Mycobacterium bovis; Mycobacterium tuberculosis; Virulence

Indexed keywords

ADRENAL GLAND; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; DISEASE COURSE; EXTRAPULMONARY TUBERCULOSIS; INFECTION RESISTANCE; INFECTION SENSITIVITY; KIDNEY; LIVER; LUNG; MALE; MOUSE; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SPLEEN; SURVIVAL TIME;

ADRENAL GLAND DISEASES; ANIMALS; MICE; MICE, INBRED BALB C; MICE, INBRED DBA; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; TUBERCULOSIS, HEPATIC; TUBERCULOSIS, PULMONARY; TUBERCULOSIS, RENAL; TUBERCULOSIS, SPLENIC; VIRULENCE;

EID: 29144485858     PISSN: 14729792     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tube.2005.04.003     Document Type: Article

References (22)

1. T. Garnier, K. Eiglmeier, J.C. Camus, N. Medina, H. Mansoor, M. Pryor, S. Duthoy, S. Grondin, C. Lacroix, C. Monsempe, S. Simon, B. Harris, R. Atkin, J. Doggett, R. Mayes, L. Keating, P.R. Wheeler, J. Parkhill, B.G. Barrell, S.T. Cole, S.V. Gordon, and R.G. Hewinson The complete genome sequence of Mycobacterium bovis Proc Natl Acad Sci USA 100 2003 7877 7882
2. L.M. O'Reilly, and C.J. Daborn The epidemiology of Mycobacterium bovis infections in animals and man: a review Tuberc. Lung Dis. 76 Suppl. 1 1995 1 46
3. D. Gavier-Widen, M.A. Chambers, N. Palmer, D.G. Newell, and R.G. Hewinson Pathology of natural Mycobacterium bovis infection in European badgers (Meles meles) and its relationship with bacterial excretion Vet Rec 148 2001 299 304
4. A. Pfeffer, B.M. Buddle, and F.E. Aldwell Tuberculosis in the brushtail possum (Trichosurus vulpecula) after intratracheal inoculation with a low dose of Mycobacterium bovis J Comp Pathol 111 1994 353 363
5. J.M. Grange Mycobacterium bovis infection in human beings Tuberculosis (Edinb) 81 2001 71 77
6. J. Francis Tuberculosis in animals and man. A study in comparative pathology 1958 Cassell and Company limited London
7. P.L. Dunn, and R.J. North Virulence ranking of some Mycobacterium tuberculosis and Mycobacterium bovis strains according to their ability to multiply in the lungs, induce lung pathology, and cause mortality in mice Infect Immun 63 1995 3428 3437
8. R.J. North, and E. Medina How important is Nramp1 in tuberculosis? Trends Microbiol 6 1998 441 442
9. R.J. North, L. Ryan, R. LaCourse, T. Mogues, and M.E. Goodrich Growth rate of mycobcteria in mice as an unreliable indicator of virulence Infect Immun 67 1999 5483 5485
10. E. Medina, and R.J. North Resistance ranking of some common inbred mouse strains to Mycobacterium tuberculosis and relationship to major histocompatibility haplotype and Nramp1 genotype Immunology 93 1998 270 274
11. R.C. Ellis, and L.A. Zabrowarny A safer staining method for acid fast bacilli J Clin Pathol 46 1993 559 560
12. E. Medina, and R.J. North Evidence inconsistent with a role for the bcg (Nramp1) gene in resistance of mice to infection with Mycobacterium tuberculosis J Exp Med 183 1996 1045 1051
13. L.M. Mitos, L.R. Cardon, A. Fortin, L. Ryan, R. LaCourse, R.J. North, and P. Gros Genetic control of susceptibility to infection with Mycobacterium tuberculosis in mice Genes Immun 1 2000 467 477
14. A.A. Chackerian, and S.M. Behar Susceptibility to Mycobacterium tuberculosis: lessons from inbred strains of mice Tuberculosis (Edinb) 83 2003 279 285
15. R.J. North, and Y.J. Jung Immunity to tuberculosis Annu Rev Immunol 22 2004 599 623
16. E. Medina, B.J. Rogerson, and R.J. North The Nramp1 antimicrobial resistance gene segregates independently of resistance to virulent Mycobacterium tuberculosis Immunology 88 1996 479 481
17. A. Casadevall, and L. Pirofski Host-pathogen interactions: the attributes of virulence J Infect Dis 184 2001 337 344
18. P.L. Dunn, and R.J. North Persistent infection with virulent but not avirulent Mycobacterium tuberculosis in the lungs of mice causes progressive pathology J Med Microbiol 45 1996 103 109
19. K.N. Lewis, R. Liao, K.M. Guinn, M.J. Hickey, S. Smith, M.A. Behr, and D.R. Sherman Deletion of RD1 from Mycobacterium tuberculosis mimics bacille Calmette-Guerin attenuation J Infect Dis 187 2003 117 123
20. S. Vidal, M.L. Tremblay, G. Govoni, S. Gauthier, G. Sebastiani, D. Malo, E. Skamene, M. Olivier, S. Jothy, and P. Gros The Ity/Lsh/Bcg locus: natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp1 gene J Exp Med 182 1995 655 666
21. S.M. Vidal, D. Malo, K. Vogan, E. Skamene, and P. Gros Natural resistance to infection with intracellular parasites: isolation of a candidate for Bcg Cell 73 1993 469 485
22. A.V. Goodchild, and R.S. Clifton-Hadley Cattle-to-cattle transmission of Mycobacterium bovis Tuberculosis (Edinb) 81 2001 23 41