Comparison of surface recognition and C3b binding properties of mouse and human complement factor H

Molecular Immunology

Volumn 43, Issue 7, 2006, Pages 972-979

  Cheng, Zhu Zhu ^a,b   Hellwage, Jens ^b   Seeberger, Harald ^b   Zipfel, Peter F ^b   Meri, Seppo ^a   Jokiranta, T Sakari ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b HANS KNÖLL INSTITUTE   (Germany)

Author keywords

Atypical hemolytic uremic syndrome (aHUS); Factor H; Human; Mouse; Regulator of complement activation

Indexed keywords

COMPLEMENT COMPONENT C3B; COMPLEMENT FACTOR H; GLYCOSAMINOGLYCAN; HEPARIN; RECOMBINANT PROTEIN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENDOTHELIUM CELL; FLOW CYTOMETRY; GENE MUTATION; HEMOLYTIC UREMIC SYNDROME; HUMAN; HUMAN CELL; PLASMA; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; SURFACE PLASMON RESONANCE;

ANIMALS; COMPLEMENT C3B; COMPLEMENT FACTOR H; ENDOTHELIAL CELLS; HEPARIN; HUMANS; MICE; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SURFACE PLASMON RESONANCE;

MURINAE;

EID: 29144485392     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2005.05.011     Document Type: Article

References (32)

1. A. Alitalo, T. Meri, T. Chen, H. Lankinen, Z.Z. Cheng, T.S. Jokiranta, I.J. Seppala, P. Lahdenne, P.S. Hefty, D.R. Akins, and S. Meri Lysine-dependent multipoint binding of the Borrelia burgdorferi virulence factor outer surface protein E to the C terminus of factor H J. Immunol. 172 2004 6195 6201
2. J. Alsenz, J.D. Lambris, T.F. Schulz, and M.P. Dierich Localization of the complement-component-C3b-binding site and the cofactor activity for factor I in the 38 kDa tryptic fragment of factor H Biochem. J. 224 1984 389 398
3. B.H. Ault Factor H and the pathogenesis of renal diseases Pediatr. Nephrol. 14 2000 1045 1053
4. T.K. Blackmore, J. Hellwage, T.A. Sadlon, N. Higgs, P.F. Zipfel, H.M. Ward, and D.L. Gordon Identification of the second heparin-binding domain in human complement factor H J. Immunol. 160 1998 3342 3348
5. A. Dahmen, T. Kaidoh, P.F. Zipfel, and I. Gigli Cloning and characterization of a cDNA representing a putative complement-regulatory plasma protein from barred sand bass (Parablax neblifer) Biochem. J. 301 1994 391 397
6. T. Demberg, B. Pollok-Kopp, D. Gerke, O. Gotze, and G. Schlaf Rat complement factor H: molecular cloning, sequencing and quantification with a newly established ELISA Scand. J. Immunol. 56 2002 149 160
7. D.L. Gordon, R.M. Kaufman, T.K. Blackmore, J. Kwong, and D.M. Lublin Identification of complement regulatory domains in human factor H J. Immunol. 155 1995 348 356
8. G.A. Hegasy, U. Willhoeft, S.A. Majno, H. Seeberger, P.F. Zipfel, and J. Hellwage Pig complement regulator factor H: molecular cloning and functional characterization Immunogenetics 55 2003 462 471
9. K. Hogasen, J.H. Jansen, T.E. Mollnes, J. Hovdenes, and M. Harboe Hereditary porcine membranoproliferative glomerulonephritis type II is caused by factor H deficiency J. Clin. Invest. 95 1995 1054 1061
10. Jarva, H., Jokiranta, T.S., Hellwage, J., Zipfel, P.F., Meri, S., 1999. Regulation of complement activation by C-reactive protein: targeting the complement inhibitory activity of factor H by an interaction with short consensus repeat domains 7 and 8-11. J. Immunol. 163, 3957-3962.
11. Jokiranta, T.S., Cheng, Z.-Z., Seeberger, H., Jòzsi, M., Heinen, S., Noris, M., Remuzzi, G., Ormsby, R., Gordon, D.L., Meri, S., Hellwage, J., Zipfel, P.F., 2005. Binding of complement factor H to endothelial cells is mediated by the carboxy-terminal glycosaminoglycan binding site. Am. J. Pathol., in press.
12. T.S. Jokiranta, J. Hellwage, V. Koistinen, P.F. Zipfel, and S. Meri Each of the three binding sites on complement factor H interacts with a distinct site on C3b J. Biol. Chem. 275 2000 27657 27662
13. C. Kemper, P.F. Zipfel, and I. Gigli The complement cofactor protein (SBP1) from the barred sand bass (Paralabrax nebulifer) mediates overlapping regulatory activities of both human C4b binding protein and factor H J. Biol. Chem. 273 1998 19398 19404
14. G. Kohler, and C. Milstein Continuous cultures of fused cells secreting antibody of predefined specificity Nature 256 1975 495 497
15. V. Koistinen, S. Wessberg, and J. Leikola Common binding region of complement factors B, H and CR1 on C3b revealed by monoclonal anti-C3d Compl. Inflamm. 6 1989 270 280
16. T. Kristensen, and B.F. Tack Murine protein H is comprised of 20 repeating units, 61 amino acids in length Proc. Natl. Acad. Sci. USA 83 1986 3963 3967
17. S. Kuhn, C. Skerka, and P.F. Zipfel Mapping of the complement regulatory domains in the human factor H-like protein 1 and in factor H1 J. Immunol. 155 1995 5663 5670
18. T. Manuelian, J. Hellwage, S. Meri, J. Caprioli, M. Noris, S. Heinen, M. Jozsi, H.P. Neumann, G. Remuzzi, and P.F. Zipfel Mutations in factor H reduce binding affinity to C3b and heparin and surface attachment to endothelial cells in hemolytic uremic syndrome J. Clin. Invest. 111 2003 1181 1190
19. S. Meri, V. Koistinen, A. Miettinen, T. Törnroth, and I.J. Seppälä Activation of the alternative pathway of complement by monoclonal l light chains in membranoproliferative glomerulonephritis J. Exp. Med. 175 1992 939 950
20. M. Okada, A. Kojima, H. Takano, Y. Harada, M. Nonaka, M. Nonaka, T. Kinoshita, T. Seya, and S.S. Natsuume Functional properties of the allotypes of mouse complement regulatory protein, factor H: difference of compatibility of each allotype with human factor I Mol. Immunol. 30 1993 841 848
21. M.K. Pangburn, and H.J. Müller-Eberhard Complement C3 convertase: cell surface restriction of b1H control and generation of restriction on neuraminidase-treated cells Proc. Natl. Acad. Sci. USA 75 1978 2416 2420
22. M.K. Pangburn, R.D. Schreiber, and H.J. Müller-Eberhard Human complement C3b inactivator: isolation, characterization, and demonstration of an absolute requirement for the serum protein b1H for cleavage of C3b and C4b in solution J. Exp. Med. 146 1977 257 270
23. M.K. Pangburn, R.D. Schreiber, and H.J. Müller-Eberhard Formation of the initial C3 convertase of the alternative complement pathway. Acquisition of C3b-like activities by spontaneous hydrolysis of the putative thioester in native C3 J. Exp. Med. 154 1981 856 867
24. D. Perez-Caballero, C. Gonzalez-Rubio, M.E. Gallardo, M. Vera, M. Lopez-Trascasa, S. Rodriguez de Cordoba, and P. Sanchez-Corral Clustering of missense mutations in the C-terminal region of factor H in atypical hemolytic uremic syndrome Am. J. Hum. Genet. 68 2001 478 484
25. M. Pickering, H. Cook, J. Warren, A. Bygrave, J. Moss, M. Walport, and M. Botto Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H Nat. Genet. 31 2002 424 428
26. W.M. Prodinger, J. Hellwage, M. Spruth, M.P. Dierich, and P.F. Zipfel The C-terminus of factor H: monoclonal antibodies inhibit heparin binding and identify epitopes common to factor H and factor H-related proteins Biochem. J. 331 1998 41 47
27. P. Sanchez-Corral, D. Perez-Caballero, O. Huarte, A.M. Simckes, E. Goicoechea, M. Lopez-Trascasa, and S.R. de Cordoba Structural and functional characterization of factor H mutations associated with atypical hemolytic uremic syndrome Am. J. Hum. Genet. 71 2002 1285 1295
28. A.K. Sharma, and M.K. Pangburn Identification of three physically and functionally distinct binding sites for C3b in human complement factor H by deletion mutagenesis Proc. Natl. Acad. Sci. USA 93 1996 10996 11001
29. C.J. Soames, A.J. Day, and R.B. Sim Prediction from sequence comparisons of residues of factor H involved in the interaction with complement component C3b Biochem. J. 315 1996 523 531
30. D. Turnberg, and M. Botto The regulation of the complement system: insights from genetically-engineered mice Mol. Immunol. 40 2003 145 153
31. J.M. Weiler, M.R. Daha, K.F. Austen, and D.T. Fearon Control of the amplification convertase of complement by the plasma protein b1H Proc. Natl. Acad. Sci. USA 73 1976 3268 3272
32. P.F. Zipfel Hemolytic uremic syndrome: how do factor H mutants mediate endothelial damage? Trends Immunol. 22 2001 345 348