Pharmacodynamics and the prediction of efficacy in short-course antibiotic therapy: Pediatric studies to validate the model

Pharmacotherapy

Volumn 25, Issue 12 II, 2005, Pages

  Bradley, John S ^a  

^a RADY CHILDREN'S HOSPITAL   (United States)

Author keywords

Monte Carlo simulation; Pharmacodynamics; Pharmacokinetics; Short course antibiotic therapy

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; AMOXICILLIN; ANTIBIOTIC AGENT; AZITHROMYCIN; CEFTRIAXONE; CLINDAMYCIN; LINEZOLID; PENICILLIN G; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

ABSCESS; ANTIBIOTIC RESISTANCE; ANTIBIOTIC THERAPY; AREA UNDER THE CURVE; BACTERIAL INFECTION; BACTERIAL MENINGITIS; BACTERIAL PNEUMONIA; BACTERICIDAL ACTIVITY; BACTERIOSTASIS; CELLULITIS; CENTRAL NERVOUS SYSTEM INFECTION; CHILD; CONFERENCE PAPER; DRUG EFFICACY; DRUG HALF LIFE; DRUG PENETRATION; DRUG TISSUE LEVEL; ENVIRONMENTAL FACTOR; ERADICATION THERAPY; HOST RESISTANCE; HUMAN; IMMUNE STATUS; IMMUNOCOMPETENCE; LOW BIRTH WEIGHT; LUNG INFECTION; MATHEMATICAL MODEL; MINIMUM INHIBITORY CONCENTRATION; MONTE CARLO METHOD; MYCOBACTERIUM; MYCOPLASMA; OTITIS MEDIA; PATIENT COMPLIANCE; PHAGOCYTOSIS; PHARMACODYNAMICS; PSEUDOMONAS AERUGINOSA; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; SALMONELLA; SHORT COURSE THERAPY; SINGLE DRUG DOSE; STREPTOCOCCUS AGALACTIAE; STREPTOCOCCUS PNEUMONIAE; STREPTOCOCCUS PYOGENES; URINARY TRACT INFECTION;

ANTI-BACTERIAL AGENTS; BACTERIAL INFECTIONS; CHILD; DRUG ADMINISTRATION SCHEDULE; DRUG RESISTANCE; HUMANS; MODELS, BIOLOGICAL; MONTE CARLO METHOD; OTITIS MEDIA;

EID: 29044449424     PISSN: 02770008     EISSN: None     Source Type: Journal    
DOI: 10.1592/phco.2005.25.12part2.159S     Document Type: Conference Paper

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