Addressing the growing problem of multiple gestations created by assisted reproductive therapies

Seminars in Perinatology

Volumn 29, Issue 5, 2005, Pages 355-362

  Nakhuda, Gary S ^a,b   Sauer, Mark V ^a  

^a Columbia University ^*  (United States)

^b PH16 ^*  (United States)

Author keywords

IVF; Multiple gestation; Twins

Indexed keywords

AROMATASE INHIBITOR; CHORIONIC GONADOTROPIN; CLOMIFENE CITRATE; GONADORELIN ANTAGONIST; GONADOTROPIN; METFORMIN; RECOMBINANT FOLLITROPIN;

ANOVULATION; ARTICLE; BIRTH ORDER; BIRTH RATE; CLINICAL TRIAL; DISEASE ASSOCIATION; DRUG SAFETY; EMBRYO TRANSFER; FERTILIZATION IN VITRO; HUMAN; INCIDENCE; INFERTILITY; INFERTILITY THERAPY; MORBIDITY; MULTIPLE PREGNANCY; NIDATION; OVARY HYPERSTIMULATION; OVULATION; OVULATION INDUCTION; PREGNANCY COMPLICATION; PREGNANCY RATE; PRIORITY JOURNAL; RISK; TWINS;

EID: 29044447865     PISSN: 01460005     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.semperi.2005.08.003     Document Type: Review

References (81)

1. From the Centers of Disease Control and Prevention Use of assisted reproductive technology-United States, 1996 and 1998 MMWR Morb Mortal Wkly Rep 51 2002 97 101
2. T.L. Callahan, J.E. Hall, S.L. Ettner The economic impact of multiple-gestation pregnancies and the contribution of assisted-reproduction techniques to their incidence N Engl J Med 331 1994 244 249
3. A.D. Elster, J.L. Bleyl, T.E. Craven Birth weight standards for triplets under modern obstetric care in the United States, 1984-1989 Obstet Gynecol 77 1991 387 393
4. R.B. Russell, J.R. Petrini, K. Damus The changing epidemiology of multiple births in the United States Obstet Gynecol 101 2003 129 135
5. Contribution of assisted reproductive technology and ovulation-inducing drugs to triplet and higher-order multiple births-United States, 1980-1997 MMWR Morb Mortal Wkly Rep 49 2000 535 538
6. A.K. Schroder, A. Katalinic, K. Diedrich Cumulative pregnancy rates and drop-out rates in a German IVF programme 4102 cycles in 2130 patients Reprod Biomed Online 8 2004 600 606
7. C. Olivius, B. Friden, G. Borg A cohort study Why do couples discontinue in vitro fertilization treatment? Fertil Steril 81 2004 258 261
8. G.L. Ryan, S.H. Zhang, A. Dokras The desire of infertile patients for multiple births Fertil Steril 81 2004 500 504
9. D.L. Hock, D.B. Seifer, E. Kontopoulos Practice patterns among board-certified reproductive endocrinologists regarding high-order multiple gestations a united states national survey Obstet Gynecol 99 2002 763 770
10. J. Dodd, C. Crowther Multifetal pregnancy reduction of triplet and higher-order multiple pregnancies to twins Fertil Steril 81 2004 1420 1422
11. J. Stone, K. Eddleman, L. Lynch A single center experience with 1000 consecutive cases of multifetal pregnancy reduction Am J Obstet Gynecol 187 2002 1163 1167
12. M.I. Evans, L. Littmann, L. St Louis Evolving patterns of iatrogenic multifetal pregnancy generation implications for aggressiveness of infertility treatments Am J Obstet Gynecol 172 1995 1750 1753 discussion 1753-1755
13. N. Gleicher, D.M. Oleske, I. Tur-Kaspa Reducing the risk of high-order multiple pregnancy after ovarian stimulation with gonadotropins N Engl J Med 343 2000 2 7
14. R. Tur, P.N. Barri, B. Coroleu Risk factors for high-order multiple implantation after ovarian stimulation with gonadotrophins evidence from a large series of 1878 consecutive pregnancies in a single centre Hum Reprod 16 2001 2124 2129
15. C. Derom, R. Derom, R. Vlietinck Iatrogenic multiple pregnancies in East Flanders, Belgium Fertil Steril 60 1993 493 496
16. M.I. Levene, J. Wild, P. Steer Higher multiple births and the modern management of infertility in Britain. The British Association of Perinatal Medicine Br J Obstet Gynaecol 99 1992 607 613
17. E. Hughes, J. Collins, P. Vandekerckhove Clomiphene citrate for unexplained subfertility in women Cochrane Database Syst Rev 2 2000 CD000057
18. N. Athaullah, M. Proctor, N.P. Johnson Oral versus injectable ovulation induction agents for unexplained subfertility Cochrane Database Syst Rev 3 2002 CD003052
19. D.S. Guzick, M.W. Sullivan, G.D. Adamson Efficacy of treatment for unexplained infertility Fertil Steril 70 1998 207 213
20. J.M. Lord, I.H. Flight, R.J. Norman Metformin in polycystic ovary syndrome systematic review and meta-analysis Br Med J 327 2003 951 953
21. I.F. Stein Sr Duration of fertility following ovarian wedge resection-Stein-Leventhal syndrome West J Surg Obstet Gynecol 72 1964 237 242
22. C.M. Farquhar, K. Williamson, P.M. Brown An economic evaluation of laparoscopic ovarian diathermy versus gonadotrophin therapy for women with clomiphene citrate resistant polycystic ovary syndrome Hum Reprod 19 2004 1110 1115
23. I. Pirwany, T. Tulandi Laparoscopic treatment of polycystic ovaries is it time to relinquish the procedure? Fertil Steril 80 2003 241 251
24. M.F. Mitwally, R.F. Casper Aromatase inhibitors for the treatment of infertility Expert Opin Investig Drugs Mar 12 2003 353 371
25. M.F. Mitwally, M.M. Biljan, R.F. Casper Pregnancy outcome after the use of an aromatase inhibitor for ovarian stimulation Am J Obstet Gynecol 192 2005 381 386
26. M.F. Mitwally, R.F. Casper Use of an aromatase inhibitor for induction of ovulation in patients with an inadequate response to clomiphene citrate Fertil Steril 75 2001 305 309
27. D.S. Guzick, S.A. Carson, C. Coutifaris Efficacy of superovulation and intrauterine insemination in the treatment of infertility. National Cooperative Reproductive Medicine Network N Engl J Med 340 1999 177 183
28. P.F. Kaplan, M. Patel, D.J. Austin Assessing the risk of multiple gestation in gonadotropin intrauterine insemination cycles Am J Obstet Gynecol 186 2002 1244 1247 discussion 1247-1249
29. R.P. Dickey, S.N. Taylor, P.Y. Lu Relationship of follicle numbers and estradiol levels to multiple implantation in 3,608 intrauterine insemination cycles Fertil Steril 75 2001 69 78
30. H.W. Jones, J.A. Schnorr Multiple pregnancies a call for action Fertil Steril 75 2001 11 13
31. B.J. Cohlen Should we continue performing intrauterine inseminations in the year 2004? Gynecol Obstet Invest 59 2005 3 13
32. G. Ragni, F. Alagna, C. Brigante GnRH antagonists and mild ovarian stimulation for intrauterine insemination a randomized study comparing different gonadotrophin dosages Hum Reprod 19 2004 54 58
33. A.M. Antman, J.A. Politch, E.S. Ginsburg Conversion of high-response gonadotropin intrauterine insemination cycles to in vitro fertilization results in excellent ongoing pregnancy rates Fertil Steril 77 2002 715 720
34. J. Nisker, I. Tummon, S. Daniel Conversion of cycles involving ovarian hyperstimulation with intra-uterine insemination to in-vitro fertilization Hum Reprod 9 1994 406 408
35. C. Albano, P. Platteau, D. Nogueira Avoidance of multiple pregnancies after ovulation induction by supernumerary preovulatory follicular reduction Fertil Steril 76 2001 820 822
36. C. De Geyter, M. De Geyter, E. Nieschlag Low multiple pregnancy rates and reduced frequency of cancellation after ovulation induction with gonadotropins, if eventual supernumerary follicles are aspirated to prevent polyovulation J Assist Reprod Genet 15 1998 111 116
37. Practice Committee of the American Society for Reproductive Medicine; Multiple pregnancy associated with infertility therapy Fertil Steril 82 suppl 1 2004 S153S157
38. V.C. Wright, L.A. Schieve, M.A. Reynolds Assisted reproductive technology surveillance-United States, 2001 MMWR CDC Surveill Summ 53 2004 1 20
39. J.C. Smulian, C.V. Ananth, W.L. Kinzler Twin deliveries in the United States over three decades an age-period-cohort analysis Obstet Gynecol 104 2004 278 285
40. Center for Disease Control Society for Assisted Reproductive Technology American Society for Reproductive Medicine 2002 Assisted Reproductive Technology Success Rates. National Summary and Fertility Clinic Reports 2005
41. P. Braude, V. Bolton, S. Moore Human gene expression first occurs between the four- and eight-cell stages of preimplantation development Nature 332 1988 459 461
42. H.B. Croxatto, B. Fuentealba, S. Diaz A simple nonsurgical technique to obtain unimplanted eggs from human uteri Am J Obstet Gynecol 112 1972 662 668
43. V.N. Bolton, M.E. Wren, J.H. Parsons Pregnancies after in vitro fertilization and transfer of human blastocysts Fertil Steril 55 1991 830 832
44. Y.J. Menezo, J.F. Guerin, J.C. Czyba Improvement of human early embryo development in vitro by coculture on monolayers of Vero cells Biol Reprod 42 1990 301 306
45. G.M. Jones, A.O. Trounson, D.K. Gardner Evolution of a culture protocol for successful blastocyst development and pregnancy Hum Reprod 13 1998 169 177
46. D. Marek, M. Langley, D.K. Gardner Introduction of blastocyst culture and transfer for all patients in an in vitro fertilization program Fertil Steril 72 1999 1035 1040
47. M. Wilson, K. Hartke, M. Kiehl Integration of blastocyst transfer for all patients Fertil Steril 77 2002 693 696
48. S. Freitas, F. Le Gal, A. Dzik [Value of cryopreservation of human embryos during the blastocyst stage] Contracept Fertil Sex 22 1994 396 401
49. L.L. Veeck, R. Bodine, R.N. Clarke High pregnancy rates can be achieved after freezing and thawing human blastocysts Fertil Steril 82 2004 1418 1427
50. D. Blake, M. Proctor, N. Johnson Cleavage stage versus blastocyst stage embryo transfer in assisted conception Cochrane Database Syst Rev 1 2005 CD002118
51. C. Staessen, P. Platteau, E. Van Assche Comparison of blastocyst transfer with or without preimplantation genetic diagnosis for aneuploidy screening in couples with advanced maternal age a prospective randomized controlled trial Hum Reprod 19 2004 2849 2858
52. M. Wilding, R. Forman, G. Hogewind Preimplantation genetic diagnosis for the treatment of failed in vitro fertilization-embryo transfer and habitual abortion Fertil Steril May 81 2004 1302 1307
53. A.H. Balen, J. MacDougall, S.L. Tan The influence of the number of embryos transferred in 1060 in-vitro fertilization pregnancies on miscarriage rates and pregnancy outcome Hum Reprod 8 1993 1324 1328
54. J. Roest, A.M. van Heusden, A. Verhoeff A triplet pregnancy after in vitro fertilization is a procedure-related complication that should be prevented by replacement of two embryos only Fertil Steril 67 1997 290 295
55. C. Staessen, C. Janssenswillen, E. Van den Abbeel Avoidance of triplet pregnancies by elective transfer of two good quality embryos Hum Reprod 8 1993 1650 1653
56. Ethics Committee of the American Fertility Society Ethical considerations of assisted reproductive technologies Fertil Steril 62 suppl 1 1994 1S 125S
57. Guidelines on the number of embryos transferred. ASRM Practice Committee report 1999 American Society for Reproductive Medicine Birmingham, AL
58. T. Jain, S.A. Missmer, M.D. Hornstein Trends in embryo-transfer practice and in outcomes of the use of assisted reproductive technology in the United States N Engl J Med 350 2004 1639 1645
59. H.W. Jones Multiple births how are we doing? Fertil Steril 79 2003 17 21
60. Practice Committee, Society for Assisted Reproductive Technology and the American Society for Reproductive Medicine Guidelines on the number of embryos transferred Fertil Steril 82 2004 773 774
61. J.A. Martin, M.M. Park Trends in twin and triplet births 1980-97 Natl Vital Stat Rep 47 1999 1 16
62. M.A. Seoud, J.P. Toner, C. Kruithoff Outcome of twin, triplet, and quadruplet in vitro fertilization pregnancies the Norfolk experience Fertil Steril 57 1992 825 834
63. Y. Yokoyama, T. Shimizu, K. Hayakawa Incidence of handicaps in multiple births and associated factors Acta Genet Med Gemellol (Roma) 44 1995 81 91
64. A. Manoura, E. Korakaki, E. Hatzidaki Perinatal outcome of twin pregnancies after in vitro fertilization Acta Obstet Gynecol Scand 83 2004 1079 1084
65. Prevention of twin pregnancies after IVF/ICSI by single embryo transfer. ESHRE Campus Course Report Hum Reprod 16 2001 790 800
66. J. Gerris, E. Van Roeyn Avoiding multiple pregnancies in ART a plea for single embryo transfer Hum Reprod 15 2000 1884 1888
67. R. Frydman, R.G. Forman, J. Belaisch-Allart An assessment of alternative policies for embryo transfer in an in vitro fertilization-embryo transfer program Fertil Steril 50 1988 466 470
68. J. Gerris, D. De Neubourg, K. Mangelschots Prevention of twin pregnancy after in-vitro fertilization or intracytoplasmic sperm injection based on strict embryo criteria a prospective randomized clinical trial Hum Reprod 14 1999 2581 2587
69. S. Vilska, A. Tiitinen, C. Hyden-Granskog Elective transfer of one embryo results in an acceptable pregnancy rate and eliminates the risk of multiple birth Hum Reprod 14 1999 2392 2395
70. D.K. Gardner, E. Surrey, D. Minjarez Single blastocyst transfer a prospective randomized trial Fertil Steril 81 2004 551 555
71. A. Thurin, J. Hausken, T. Hillensjo Elective single-embryo transfer versus double-embryo transfer in in vitro fertilization N Engl J Med 351 2004 2392 2402
72. L.A. Schieve, S.F. Meikle, C. Ferre Low and very low birth weight in infants conceived with use of assisted reproductive technology N Engl J Med 346 2002 731 737
73. F.M. Helmerhorst, D.A. Perquin, D. Donker Perinatal outcome of singletons and twins after assisted conception a systematic review of controlled studies Br Med J 328 2004 261
74. H.W. Jones Jr, J. Cohen IFFS surveillance 01 Fertil Steril 76 Suppl 3 2001 S5 S36
75. M.E. Jones, M.L. Bond, S.H. Gardner A call to action. Acculturation level and family-planning patterns of Hispanic immigrant women MCN Am J Matern Child Nurs 27 2002 26 32 quiz 33
76. P. Saldeen, P. Sundstrom Would legislation imposing single embryo transfer be a feasible way to reduce the rate of multiple pregnancies after IVF treatment? Hum Reprod 20 2005 4 8
77. O.K. Davis Elective single-embryo transfer-has its time arrived? N Engl J Med 351 2004 2440 2442
78. J.K. Min, S.A. Breheny, V. MacLachlan What is the most relevant standard of success in assisted reproduction? The singleton, term gestation, live birth rate per cycle initiated the BESST endpoint for assisted reproduction Hum Reprod 19 2004 3 7
79. P. Doyle The outcome of multiple pregnancy Hum Reprod 11 suppl 4 1996 110 117 discussion 118-120
80. M. Garel, E. Chavanne-De Weck, B. Blondel [Psychological consequences of twinship on the children and their parents] J Gynecol Obstet Biol Reprod (Paris) 31 suppl 2002 2S40 2S45
81. T. Jain, B.L. Harlow, M.D. Hornstein Insurance coverage and outcomes of in vitro fertilization N Engl J Med 347 2002 661 666