Quantitative simultaneous 99mTc-ECD/123I-FP-CIT SPECT in Parkinson's disease and multiple system atrophy

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 33, Issue 1, 2006, Pages 87-92

  El Fakhri, Georges ^a   Habert, Marie Odile ^b   Maksud, Philippe ^b   Kas, Aurélie ^b   Malek, Zoulikha ^b   Kijewski, Marie Foley ^a   Lacomblez, Lucette ^b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

123I FP CIT; 99mTc ECD; Dual isotope SPECT; Idiopathic Parkinson's disease; Multiple system atrophy

Indexed keywords

CYSTEINE ETHYL ESTER TC 99M; IODINE 123;

ADULT; AGED; ARTICLE; BINDING AFFINITY; CAUDATE NUCLEUS; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CORPUS STRIATUM; DIFFERENTIAL DIAGNOSIS; DOPAMINERGIC TRANSMISSION; FEASIBILITY STUDY; FEMALE; HUMAN; MALE; NEUTRON SCATTERING; PARKINSON DISEASE; PERFUSION; PUTAMEN; SHY DRAGER SYNDROME; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; STATISTICAL PARAMETERS; STATISTICAL SIGNIFICANCE;

CYSTEINE; DIAGNOSIS, DIFFERENTIAL; FEASIBILITY STUDIES; FEMALE; HUMANS; IMAGE ENHANCEMENT; MALE; MIDDLE AGED; MULTIPLE SYSTEM ATROPHY; ORGANOTECHNETIUM COMPOUNDS; PARKINSON DISEASE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TROPANES;

EID: 28944439106     PISSN: 16197070     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-005-1920-y     Document Type: Article

References (10)

1. El Fakhri G, Maksud P, Kijewski MF, Habert MO, Todd-Pokropek A, Aurengo A, et al. Scatter and cross-talk corrections in simultaneous Tc-99m/I-123 brain SPECT using constrained factor analysis and artificial neural networks. IEEE Trans Nucl Sci 2000;47:1573-80
2. El Fakhri G, Moore SC, Maksud P, Aurengo A, Kijewski MF. Absolute activity quantitation in simultaneous I-123/Tc-99m brain SPECT. J Nucl Med 2001;42:300-8
3. Hughes AJ, Daniel SE, Kilford L, Lees AJ. Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinicopathological study of 100 cases. J Neurol Neurosurg Psychiatry 1992;55:1009-13
4. Gilman S, Low PA, Quinn N, Albanese A, Ben-Shlomo Y, Fowler CJ, et al. Consensus statement on the diagnosis of multiple system atrophy. J Neurol Sci 1999;163:94-8
5. Friston KJ, Holmes AP, Worsley KJ, Poline JB, Frith C, Frackowiak R. Statistical parametric maps in functional imaging: a general linear approach. Hum Brain Mapp 1995;2:189-210
6. Cointepas Y, Mangin JF, Garnero L, Poline JB, Benali H. Brain VISA: software platform for visualization and analysis of multi-modality brain data. Neuroimage 2001;13:S98
7. Tzourio-Mazoyer N, Landeau B, Papathanassiou D, Crivello F, Etard O, Delcroix N, et al. Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. Neuroimage 2002;15:273-89
8. 99mTc]TRODAT-1 SPECT binding to dopamine transporters in patients with multiple system atrophy and Parkinson's disease. Eur J Nucl Med Mol Imaging 2004;32:302-7
9. Thobois S, Jahanshahi M, Pinto S, Frackowiak R, Limousin-Dowseya P. PET and SPECT functional imaging studies in parkinsonian syndromes: from the lesion to its consequences. Neurolmage 2004;23:1-16
10. 99mTc-ECD brain perfusion SPET allows accurate differentiation between healthy volunteers, multiple system atrophy and idiopathic Parkinson's disease. Eur J Nucl Med 2003;30:16-24