Iron-regulatory protein hepcidin is increased in female athletes after a marathon

European Journal of Applied Physiology

Volumn 95, Issue 5-6, 2005, Pages 569-571

  Roecker, L ^a   Meier Buttermilch, R ^a   Brechtel, L ^b   Nemeth, E ^c   Ganz, T ^c  

^a Medizinisches Versorgungszentrum   (Germany)

^b HUMBOLDT UNIVERSITY   (Germany)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Females; Hepcidin; Iron metabolism; Marathon

Indexed keywords

CREATININE; HEPCIDIN; IRON; IRON REGULATORY FACTOR;

ADULT; ARTICLE; FEMALE; GENDER; HUMAN; HUMAN EXPERIMENT; IRON DEFICIENCY; IRON METABOLISM; MARATHON RUNNER; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN SECRETION; URINALYSIS;

ADULT; ANTIMICROBIAL CATIONIC PEPTIDES; FEMALE; HUMANS; IRON; PHYSICAL ENDURANCE; RUNNING;

EID: 28844502297     PISSN: 14396319     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00421-005-0055-y     Document Type: Article

References (14)

1. Abarbanel J, Benet AE, Lask D, Kimche D (1990) Sports hematuria. J Urol 143:887-890 2184253
2. Brownlie T, Untermohlen V, Hinton PS, Haas JD (2004) Tissue iron deficiency without anemia impairs adaption in endurance capacity after aerobic training in previously untrained women. Am J Clin Nutr 79:437-443 14985219
3. Ganz T (2005) Hepcidin - a regulator of intestinal iron absorption and iron recycling by macrophages. Best Pract Res Clin Haematol 18:171-182 10.1016/j.beha.2004.08.020
4. Magnusson B, Hallberg L, Rossander L, Swolin B (1984) Iron Metabolism and - Sports Anemia'. II A Hematological comparison of elite runners and control subjects. Acta Med Scand 216:157-164 6496175
5. Mattusch F, Dufaux B, Heine O, Mertens I, Rost R (2000) Reduction of the plasma concentration of c-reactive protein following nine month of endurance training. Int J Sports Med 21:21-24 10.1055/s-2000-8852
6. Nemeth E, Valore EV, Territo M, Schiller G, Lichtenstein A, Ganz T (2003) Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein. Blood 101:2461-2463 10.1182/ blood-2002-10-3235
7. Nemeth E, Rivera S, Gabayan V, Keller CH, Taudorf S, Pedersen BK, Ganz T (2004) IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. J Clin Invest 113:1271-1276 10.1172/JCI200420945
8. Northoff H, Berg A (1991) Immunologie mediators as parameters of the reaction to strenuous exercise. Int J Sports Med 12:9-15
9. Pedersen BK, Hoffmann-Gortz L (2000) Exercise and the immune system: regulation, integration and adaptation. Physiol Rev 80:1055-1081 10893431
10. Roecker L, Hinz K, Holland K, Gunga H-CH, Vogelgesang J, Kiesewetter H (2002) Influence of endurance exercise (triathlon) on circulating transferrin receptors and other indicators of iron status in female athletes. Clin Lab 48:30-312 120715817
11. Schumacher YO, Schmid A, Grathwohl D, Bultermann D, Berg A (2002) Hematological indices and iron status in athletes of various sports and performances. Med Sci Sports Exerc 34:869-875 10.1097/ 00005768-200205000-00022
12. Shaskey J, Green GA (2000) Sports heamatology. Sports Med 29:27-38 10688281
13. Stewart JG, Ahlquist DA, McGill DB, Ilstrup DM, Schwartz S, Owen RA (1984) Gastrointestinal blood loss and anemia in runners. Ann Intern Med 100:843-845 6609656
14. Weight LM, Byrne MJ, Jacobs P (1991) Haemolytic effects of exercise. Clin Sci 81:147-152 1653657