Alternative pathway of metronidazole activation in Trichomonas vaginalis hydrogenosomes

Antimicrobial Agents and Chemotherapy

Volumn 49, Issue 12, 2005, Pages 5033-5036

  Hrdý, Ivan ^a   Cammack, Richard ^b   Stopka, Pavel ^c   Kulda, Jaroslav ^a   Tachezy, Jan ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c INSTITUTE OF INORGANIC CHEMISTRY   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

4 NITROIMIDAZOLE; CARBON DIOXIDE; DRUG CARRIER; HYDROGENASE; MALATE DEHYDROGENASE (DECARBOXYLATING); METRONIDAZOLE; NICOTINAMIDE ADENINE DINUCLEOTIDE; PYRUVIC ACID;

ARTICLE; CATALYSIS; CONTROLLED STUDY; DECARBOXYLATION; DRUG ABSORPTION; DRUG CYTOTOXICITY; DRUG ELIMINATION; ELECTRON TRANSPORT; ENZYME SUBSTRATE; FLAGELLATE; HUMAN; HUMAN CELL; HUMAN TISSUE; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; TRICHOMONAS VAGINALIS; TRICHOMONIASIS; UROGENITAL TRACT INFECTION;

ANIMALS; ANTITRICHOMONAL AGENTS; DRUG RESISTANCE; METRONIDAZOLE; ORGANELLES; TRICHOMONAS VAGINALIS;

EID: 28844497273     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.49.12.5033-5036.2005     Document Type: Article

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