Gene therapy with human osteoprotegerin decreases callus remodeling with limited effects on biomechanical properties

Bone

Volumn 37, Issue 6, 2005, Pages 751-758

  Ulrich Vinther, Michael ^a   Schwarz, Edward M ^b   Pedersen, Finn S ^c   Søballe, Kjeld ^a   Andreassen, Troels T ^c  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^c AARHUS UNIVERSITY   (Denmark)

Author keywords

AAV; Fracture healing; Gene therapy; Osteoprotegerin

Indexed keywords

GREEN FLUORESCENT PROTEIN; OSTEOPROTEGERIN; PARVOVIRUS VECTOR; RECOMBINANT CYTOKINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; BONE REMODELING; BONE STRENGTH; BONE STRESS; CALLUS; CELL COUNT; CELL FUNCTION; CELL MATURATION; CELL SURVIVAL; CHRONIC DISEASE; CONTROLLED STUDY; CORTICAL BONE; DRUG BLOOD LEVEL; DRUG EFFECT; EMBRYO; FEMALE; GENE CONSTRUCT; GENE TARGETING; GENE THERAPY; GENETIC TRANSDUCTION; HISTOLOGY; HUMAN; HUMAN CELL; LONG TERM CARE; MATERIALS; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; OSTEOPOROSIS; PROTEIN BLOOD LEVEL; RAT; RECIPIENT; REPORTER GENE; TIBIA FRACTURE; TISSUE STRUCTURE; YOUNG MODULUS;

ANIMALS; BIOMECHANICS; BODY WEIGHT; BONE REMODELING; BONY CALLUS; FEMALE; FRACTURES, BONE; GENE THERAPY; GLYCOPROTEINS; HUMANS; OSTEOPROTEGERIN; RATS; RATS, WISTAR; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, TUMOR NECROSIS FACTOR; TIBIA;

EID: 28844473010     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2005.07.021     Document Type: Article

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