Inter-population variations in concentrations, determinants of and correlations between 2,2′,4,4′,5,5′-hexachlorobiphenyl (CB-153) and 1,1-dichloro-2,2-bis (p-chlorophenyl)-ethylene (p,p′-DDE): A cross-sectional study of 3161 men and women from Inuit and European populations

Environmental Health: A Global Access Science Source

Volumn 4, Issue , 2005, Pages

  Jönsson, Bo A G ^a   Rylander, Lars ^a   Lindh, Christian ^a   Rignell Hydbom, Anna ^a   Giwercman, Aleksander ^a   Toft, Gunnar ^b   Pedersen, Henning S ^c   Ludwicki, Jan K ^d   Góralczyk, Katarzyna ^d   Zvyezday, Valentyna ^e   Spanò, Marcello ^f   Bizzaro, Davide ^g   Bonefeld Jörgensen, Eva C ^h   Manicardi, Gian Carlo ⁱ   Bonde, Jens Peter ^b   Hagmar, Lars ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b AARHUS UNIVERSITY HOSPITAL   (Denmark)

^c Centre for Arctic Environmental Medicine   (Denmark)

^d NATIONAL INSTITUTE OF HYGIENE   (Poland)

^e KHARKIV NATIONAL MEDICAL UNIVERSITY   (Ukraine)

^f ENEA C R CASACCIA   (Italy)

^g UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^h AARHUS UNIVERSITY   (Denmark)

ⁱ UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

1,1 DICHLORO 2,2 BIS(4 CHLOROPHENYL)ETHYLENE; 2,2',4,4',5,5' HEXACHLOROBIPHENYL; BIOLOGICAL MARKER; LIPID;

ADOLESCENT; ADULT; ARTICLE; CHILD; CONTROLLED STUDY; CORRELATION COEFFICIENT; ESKIMO; EUROPE; FEMALE; FISHERMAN; GAS CHROMATOGRAPHY; HUMAN; MALE; MASS SPECTROMETRY; POLAND; SMOKING HABIT; SWEDEN; UKRAINE;

ADULT; BIOLOGICAL MARKERS; DICHLORODIPHENYL DICHLOROETHYLENE; ENDOCRINE SYSTEM; ENVIRONMENTAL POLLUTANTS; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; FERTILITY; FOOD CHAIN; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GREENLAND; HUMANS; HYDROCARBONS, CHLORINATED; INUITS; MALE; MIDDLE AGED; POLAND; POLYCHLORINATED BIPHENYLS; SEAFOOD; SPERMATOZOA; SWEDEN; UKRAINE;

EID: 28844459043     PISSN: 1476069X     EISSN: 1476069X     Source Type: Journal    
DOI: 10.1186/1476-069X-4-27     Document Type: Article

References (49)

1. Toppari J, Larsen JC, Christiansen P, Giwercman A, Grandjean P, Guillette LJ Jr, Jegou B, Jensen TK, Jouannet P, Keiding N, Leffers H, McLachlan JA, Meyer O, Muller J, Rajpert-De Meyts E, Scheike T, Sharpe R, Sumpter J, Skakkebaek NE: Male reproductive health and environmental xenoestrogens. Environ Health Perspect 1996, 104(Suppl 4):741-803.
2. Kelce WR, Stone CR, Laws SC, Gray LE, Kemppainen JA, Wilson EM: Persistent DDT metabolite p,p′-DDE is a potent androgen receptor antagonist. Nature 1995, 375:581-585.
3. Danzo BJ: Environmental xenobiotics may disrupt normal endocrine function by interfering with the binding of physiological ligands to steroid receptors and binding proteins. Environ Health Perspect 1997, 105:294-301.
4. Bonefeld-Jorgensen EC, Andersen HR, Rasmussen TH, Vinggaard AM: Effect of highly bioaccumulated polychlorinated biphenyl congeners on estrogen and androgen receptor activity. Toxicology 2001, 158:141-153.
5. Toft G, Hagmar L, Giwercman A, Bonde JP: The epidemiological evidence on reproductive effects of biopersistent organochlorines in humans. Reprod Toxicol 2004, 19:5-26.
6. Toft G, Axmon A, Giwercman A, Thulstrup AM, Rignell-Hydbom A, Sloth Pedersen H, Ludwicki JK, Zvyesday V, Spano M, Manicardi GC, Bonefeld-Jorgensen EC, Hagmar L, Bonde JP, INUENDO: Fertility in four regions spanning large contrasts in serum levels of wide-spread persistent organochlorines. Environmental Health 2005, 4:26.
7. Arctic Monitoring and Assessment Programme: Human Health in the Arctic, Arctic Monitoring and Assessment Programme (AMAP), Oslo 2003 [http://www.amap.no].
8. Svensson B-G, Nilsson A, Jonsson E, Schütz A, Åkesson B, Hagmar L: Fish consumption and exposure to persistent organochlorine compounds, mercury, selenium and methylamines in Swedish fishermen. Scand J Work Environ Health 1995, 21:94-103.
9. Rylander L, Hagmar L: Mortality and cancer incidence among women with a high consumption of fatty fish contaminated with persistent organochlorine compounds. Scand J Work Environ Health 1995, 21:419-426.
10. Czaja K, Ludwicki JK, Góralczyk K, Struciñski P: Organochlorine pesticides, HCB, and PCBs in human milk in Poland. Bull Environ Contam Toxicol 1997, 58:769-775.
11. Gladen BC, Shkiryak-Nyzhnyk ZA, Chyslovska N, Zadorozhnaja TD, Little RE: Persistent organochlorine compounds and birth weight. Ann Epidemiol 2003, 13:151-157.
12. Grimvall W, Rylander L, Nilsson-Ehle P, Nilsson U, Strömberg U, Hagmar L, Östman C: Monitoring of polychlorinated biphenyls in human blood plasma with respect to age, lactation and fish consumption; methodology developments. Arch Environ Contam Toxicol 1997, 32:329-336.
13. Glynn AW, Wolk A, Aune M, Atuma S, Zettermark S, Maehle-Schmid M, Darnerud PO, Becker W, Vessby B, Adami HOl: Serum concentrations of organochlorines in men: a search for markers of exposure. Sci Total Environ 2000, 263:197-208.
14. Deutch B, Pedersen HS, Jorgensen EC, Hansen JC: Smoking as a determinant of high organochlorine levels in Greenland. Arch Environ Health 2003, 58:30-36.
15. Muckle G, Ayotte P, Dewailly E, Jacobson SW, Jacobson JL: Determinants of polychlorinated biphenyls and methylmercury exposure in Inuit women of childbearing age. Environ Health Perspect 2001, 109:957-963.
16. Rignell-Hydbom A, Rylander L, Giwercman A, Jönsson BAG, Nilsson-Ehle P, Hagmar L: Exposure to CB-153 and p,p′-DDE and male reproductive function. Human Reprod 2004, 19:2066-2075.
17. Rylander L, Nilsson-Ehle P, Hagmar L: A simplified precise method for adjusting serum levels of persistent organohalogen pollutants to total serum lipids. Chemosphere in press. 2005 Jul 7
18. Altman DG: Practical statistics for medical research London: Chapman and Hall; 1991.
19. Bjerregaard P, Dewailly E, Ayotte P, Pars T, Ferron L, Mulvad G: Exposure of Inuit in Greenland to organochlorines through the marine diet. J Toxicol Environ Health A 2001, 62:69-81.
20. Falk C, Hanrahan L, Anderson HA, Kanarek MS, Draheim L, Needham L, Patterson D Jr: Body burden levels of dioxin, furans, and PCBs among frequent consumers of Great Lakes sport fish. The Great Lakes Consortium. Environ Res 1999, 80:S19-S25.
21. Hunter DJ, Hankinson SE, Laden F, Colditz GA, Manson JE, Willett WC, Speizer FE, Wolff MS: Plasma organochlorine levels and the risk of breast cancer. N Engl J Med 1997, 337:1253-1258.
22. Rylander L, Dyremark E, Strömberg U, Östman C, Hagmar L: The impact of age, lactation and dietary habits on PCB in plasma in Swedish women. Sci Total Environ 1997, 207:55-61.
23. Wolff MS, Zeleniuch-Jacquotte A, Dubin N, Toniolo P: Risk of breast cancer and organochlorine exposure. Cancer Epidemiol Biomark Prev 2000, 9:271-7.
24. Laden F, Neas LM, Spiegelman D, Hankinson SE, Willett WC, Ireland K, Wolff MS, Hunter DJ: Predictors of plasma concentrations of DDE and PCBs in a group of U.S. women. Environ Health Perspect 1999, 107:75-81.
25. Rogan WJ, Gladen BC, McKinney JD, Carreras N, Hardy P, Thullen J, Tingelstad J, Tully M: Polychlorinated biphenyls (PCBs) and dichlorodiphenyl dichloroethene (DDE) in human milk: effects of maternal factors and previous lactation. Am J Public Health 1986, 76:172-177.
26. Skaare JU, Polder A: Polychlorinated biphenyls and organochlorine pesticides in milk of Norwegian women during lactation. Arch Environ Contam Toxicol 1990, 19:640-645.
27. Hong CS, Xiao J, Casey AC, Bush B, Fitzgerald EF, Hwang SA: Mono-ortho-and non-ortho-substituted polychlorinated biphenyls in human milk from Mohawk and control women: effects of maternal factors and previous lactation. Arch Environ Contam Toxicol 1994, 27:431-437.
28. Bignert A, Olsson M, Persson W, Jensen S, Zakrisson S, Litzén K, Eriksson U, Haggberg L, Alsberg T: Temporal trends of organochlorines in Northern Europe, 1967-1995. Relation to global fractionation, leakage from sediments and international measures. Environ Pollut 1998, 99:177-198.
29. Glynn AW, Granath F, Aune M, Atuma S, Darnerud PO, Bjerselius R, Vainio H, Weiderpass E: Organochlorines in Swedish women: determinants of serum concentrations. Environ Health Perspect 2003, 111:349-355.
30. Schildkraut JM, Demark-Wahnefried W, DeVoto E, Hughes C, Laseter JL, Newman B: Environmental contaminants and body fat distribution. Cancer Epidemiol Biomark Prev 1999, 8:179-83.
31. Wolff MS, Berkowitz GS, Brower S, Senie R, Bleiweiss IJ, Tartter P, Pace B, Roy N, Wasllenstein S, Weston A: Organochlorine exposures and breast cancer risk in New York City women. Environ Res 2000, 84:151-161.
32. Dorgan JF, Brock JW, Rothman N, Needham LL, Miller R, Stephenson HE Jr, Schussler N, Taylor PR: Serum organochlorine pesticides and PCBs and breast cancer risk: results from a prospective analysis (USA). Cancer Causes Control 1999, 10:1-11.
33. Wolff MS, Anderson HA: Correspondence re: J. M. Schildkraut et al., Environmental contaminants and body fat distribution. Cancer Epidemiol Biomark Prev 1999, 8:951-952.
34. Deutch B, Hansen JC: High human plasma levels of organochlorine compounds in Greenland. Regional differences and lifestyle effects. Dan Med Bull 2000, 47:132-137.
35. Pereg D, Dewailly E, Poirier GG, Ayotte P: Environmental exposure to polychlorinated biphenyls and placental CYP1A1 activity in Inuit women from northern Quebec. Environ Health Perspect 2002, 110:607-612.
36. Deutch B, Pedersen HS, Hansen JC: Dietary composition in Greenland plasma fatty acids and persistent organic pollutants. Sci Total Environ 2000, 331:177-188.
37. Dewailly E, Ryan JJ, Laliberté C, Bruneau S, Weber J-P, Gingras S, Carrier G: Exposure of remote maritime populations to coplanar PCBs. Environ Health Perspect 1994, 102(suppl 1):205-209.
38. Arctic Monitoring and Assessment Programme:. In Assessment report: Arctic pollution issues Volume xii. Oslo, Norway; 1998:859.
39. Bjerregaard P, Hansen JC: Organochlorines and heavy metals in prgnant women from the Disko Bay area in Greenland. Sci Tot Environ 2000, 245:195-202.
40. Noren K: Contemporary and retrospective investigations of human milk in the trend studies of organochlorine contaminants in Sweden. Sci Total Environ 1993, 139-140:347-355.
41. Schade G, Heinzow B: Organochlorine pesticides and polychlorinated biphenyls in human milk of mothers living in northern Germany: current extent of contamination, time trend from 1986 to 1997 and factors that influence the levels of contamination. Sci Total Environ 1998, 215:31-39.
42. Waliszewski SM, Aguirre AA, Infanzon RM, Rivera J, Infanzon R: Time trend of organochlorine pesticide residues in human adipose tissue in Veracruz, Mexico: 1988-1997 survey. Sci Total Environ 1998, 221:201-204.
43. Harris CA, O'Hagan S, Merson GH: Organochlorine pesticide residues in human milk in the United Kingdom 1997-8. Hum Exp Toxicol 1999, 18:602-606.
44. Noren K, Meironyte D: Certain organochlorine and organobromine contaminants in Swedish human milk in perspective of past 20-30 years. Chemosphere 2000, 40:1111-23.
45. He JP, Stein AD, Humphrey HE, Paneth N, Courval JM: Time trends in sport-caught Great Lakes fish consumption and serum polychlorinated biphenyl levels among Michigan Anglers, 1973-1993. Environ Sci Technol 2001, 35:435-440.
46. Dallaire F, Dewailly É, Laliberte C, Muckle G, Ayotte P: Temporal trends of organochlorine concentrations in umbilical cord blood of newborns from the lower north shore of the St. Lawrence river (Québec, Canada). Environ Health Perspect 2002, 110:835-838.
47. Dallaire F, Dewailly É, Muckle G, Ayotte P: Time trends of persistent organic pollutants and heavy metals in umbilical cord blood of Inuit infants born in Nunavik (Québec, Canada) between 1994 and 2001. Environ Health Perspect 2003, 111:1660-1664.
48. Asplund L, Svensson BG, Nilsson A, Eriksson U, Jansson B, Jensen S, Wideqvist U, Skerfving S: Polychlorinated biphenyls, 1,1,1-trichloro-2,2-bis(p- chlorophenyl)ethane (p,p′-DDT) and 1,1-dichloro-2,2-bis(p-chlorophenyl)- ethylene (p,p′-DDE) in human plasma related to fish consumption. Arch Environ Health 1994, 49:477-486.
49. Sjödin A, Hagmar L, Klasson-Wehler E, Björk J, Bergman Å: Influence of the consumption of fatty Baltic Sea fish on plasma levels of halogenated environmental contaminants in Latvian and Swedish men. Environ Health Perspect 2000, 108:1035-1040.