-
1
-
-
0032145202
-
Use of L-asparaginase in childhood ALL
-
Muller HJ, Boos J. Use of L-asparaginase in childhood ALL. Crit Rev Oncol Hematol 1998;28:97-113.
-
(1998)
Crit Rev Oncol Hematol
, vol.28
, pp. 97-113
-
-
Muller, H.J.1
Boos, J.2
-
2
-
-
0030764521
-
Acute lymphoblastic leukaemia: A guide to asparaginase and pegaspargase therapy
-
Ettinger LJ, Ettinger AG, Avramis VI, et al. Acute lymphoblastic leukaemia: A guide to asparaginase and pegaspargase therapy. Bio Drugs 1997;7:30-39.
-
(1997)
Bio Drugs
, vol.7
, pp. 30-39
-
-
Ettinger, L.J.1
Ettinger, A.G.2
Avramis, V.I.3
-
3
-
-
0027536607
-
L-asparaginase and PEG asparaginase-Past, present, and future
-
Keating MJ, Holmes R, Lerner S, et al. L-asparaginase and PEG asparaginase-Past, present, and future. Leuk Lymphoma 1993;10:153-157.
-
(1993)
Leuk Lymphoma
, vol.10
, pp. 153-157
-
-
Keating, M.J.1
Holmes, R.2
Lerner, S.3
-
5
-
-
0014424759
-
Asparagine synthetase in normal and malignant tissues: Correlation with tumor sensitivity to asparaginase
-
Prager MD, Bachynsky N. Asparagine synthetase in normal and malignant tissues: Correlation with tumor sensitivity to asparaginase. Arch Biochem Biophys 1968;127:645-654.
-
(1968)
Arch Biochem Biophys
, vol.127
, pp. 645-654
-
-
Prager, M.D.1
Bachynsky, N.2
-
6
-
-
0001372550
-
The requirement for L-asparagine of mouse leukemia cells L5178Yin culture
-
Haley EE, Fischer GA, Welch AD. The requirement for L-asparagine of mouse leukemia cells L5178Yin culture. Cancer Res 1961;21:532-536.
-
(1961)
Cancer Res
, vol.21
, pp. 532-536
-
-
Haley, E.E.1
Fischer, G.A.2
Welch, A.D.3
-
8
-
-
0017253880
-
Hypersensitive reactions and antibody formation during L-asparaginase treatment of children and adults with acute leukemia
-
Killander D, Dohlwitz A, Engstedt L, et al. Hypersensitive reactions and antibody formation during L-asparaginase treatment of children and adults with acute leukemia. Cancer 1976;37:220-228.
-
(1976)
Cancer
, vol.37
, pp. 220-228
-
-
Killander, D.1
Dohlwitz, A.2
Engstedt, L.3
-
9
-
-
0020080755
-
Anaphylactoid reactions to Escherichia coli and Erwinia asparaginase in children with leukemia and lymphoma
-
Evans WE, Tsiatis A, Rivera G, et al. Anaphylactoid reactions to Escherichia coli and Erwinia asparaginase in children with leukemia and lymphoma. Cancer 1982;49:1378-1383.
-
(1982)
Cancer
, vol.49
, pp. 1378-1383
-
-
Evans, W.E.1
Tsiatis, A.2
Rivera, G.3
-
10
-
-
0000973839
-
Antibodies to asparaginase alter pharmacokinetics and decrease enzyme activity in patients on asparaginase therapy
-
Kurtzberg J, Asselin B, Poplack D, et al. Antibodies to asparaginase alter pharmacokinetics and decrease enzyme activity in patients on asparaginase therapy. Proc Am Assoc Cancer Res 1993;34:304.
-
(1993)
Proc Am Assoc Cancer Res
, vol.34
, pp. 304
-
-
Kurtzberg, J.1
Asselin, B.2
Poplack, D.3
-
11
-
-
0002904434
-
A new look at PEG-L-asparaginase and other asparaginases in hematological malignancies
-
Kurtzberg J. A new look at PEG-L-asparaginase and other asparaginases in hematological malignancies. Cancer Investigation 1994;12:59-60.
-
(1994)
Cancer Investigation
, vol.12
, pp. 59-60
-
-
Kurtzberg, J.1
-
12
-
-
0019461927
-
Reduction in immunogenicity and clearance rate of Escherichia coli L-asparaginase by modification with monomethoxypolyethylene glycol
-
Kamisaki Y, Wada H, Yagura T, et al. Reduction in immunogenicity and clearance rate of Escherichia coli L-asparaginase by modification with monomethoxypolyethylene glycol. J Pharmacol Exp Ther 1981;216:410-414.
-
(1981)
J Pharmacol Exp Ther
, vol.216
, pp. 410-414
-
-
Kamisaki, Y.1
Wada, H.2
Yagura, T.3
-
13
-
-
0036861899
-
Immunogenicity of therapeutic proteins: Clinical implications and future prospects
-
Schellekens H. Immunogenicity of therapeutic proteins: Clinical implications and future prospects. Clin Ther 2002;24:1720-1740.
-
(2002)
Clin Ther
, vol.24
, pp. 1720-1740
-
-
Schellekens, H.1
-
14
-
-
0022922655
-
Clinical pharmacology of polyethylene glycol-L-asparaginase
-
Ho DH, Brown NS, Yen A, et al. Clinical pharmacology of polyethylene glycol-L-asparaginase. Drug Metab Dispos 1986;14:349-352.
-
(1986)
Drug Metab Dispos
, vol.14
, pp. 349-352
-
-
Ho, D.H.1
Brown, N.S.2
Yen, A.3
-
15
-
-
0027197614
-
Comparative pharmacokinetic studies of three asparaginase preparations
-
Asselin BL, Whitin JC, Coppola DJ, et al. Comparative pharmacokinetic studies of three asparaginase preparations. J Clin Oncol 1993;11:1780-1786.
-
(1993)
J Clin Oncol
, vol.11
, pp. 1780-1786
-
-
Asselin, B.L.1
Whitin, J.C.2
Coppola, D.J.3
-
16
-
-
0030218821
-
Monitoring of asparaginase activity and asparagine levels in children on different asparaginase preparations
-
Boos J, Werber G, Ahlke E, et al. Monitoring of asparaginase activity and asparagine levels in children on different asparaginase preparations. Eur J Cancer 1996;32A:1544-1550.
-
(1996)
Eur J Cancer
, vol.32
, pp. 1544-1550
-
-
Boos, J.1
Werber, G.2
Ahlke, E.3
-
17
-
-
0031049365
-
Dose reduction of asparaginase under pharmacokinetic and pharmacodynamic control during induction therapy in children with acute lymphoblastic leukaemia
-
Ahlke E, Nowak-Gottl U, Schulze-Westhoff P, et al. Dose reduction of asparaginase under pharmacokinetic and pharmacodynamic control during induction therapy in children with acute lymphoblastic leukaemia. Br J Haematol 1997;96:675-681.
-
(1997)
Br J Haematol
, vol.96
, pp. 675-681
-
-
Ahlke, E.1
Nowak-Gottl, U.2
Schulze-Westhoff, P.3
-
18
-
-
0344699390
-
Pharmacokinetic dose adjustment of Erwinia asparaginase in protocol II of the paediatric ALL/NHL-BFM treatment protocols
-
Vieira Pinheiro JP, Ahlke E, Nowak-Gottl U, et al. Pharmacokinetic dose adjustment of Erwinia asparaginase in protocol II of the paediatric ALL/NHL-BFM treatment protocols. Br J Haematol 1999;104:313-320.
-
(1999)
Br J Haematol
, vol.104
, pp. 313-320
-
-
Vieira Pinheiro, J.P.1
Ahlke, E.2
Nowak-Gottl, U.3
-
19
-
-
0033836246
-
Pegylated asparaginase (Oncaspar) in children with ALL: Drug monitoring in reinduction according to the ALL/NHL-BFM 95 protocols
-
Muller HJ, Loning L, Horn A, et al. Pegylated asparaginase (Oncaspar) in children with ALL: Drug monitoring in reinduction according to the ALL/NHL-BFM 95 protocols. Br J Haematol 2000;110:379-384.
-
(2000)
Br J Haematol
, vol.110
, pp. 379-384
-
-
Muller, H.J.1
Loning, L.2
Horn, A.3
-
20
-
-
17544399852
-
L-asparagine depletion and L-asparaginase activity in children with acute lymphoblastic leukemia receiving i.m. or i.v. Erwinia C. or E. coli L-asparaginase as first exposure
-
Rizzari C, Zucchetti M, Conter V, et al. L-asparagine depletion and L-asparaginase activity in children with acute lymphoblastic leukemia receiving i.m. or i.v. Erwinia C. or E. coli L-asparaginase as first exposure. Ann Oncol 2000;11:189-193.
-
(2000)
Ann Oncol
, vol.11
, pp. 189-193
-
-
Rizzari, C.1
Zucchetti, M.2
Conter, V.3
-
21
-
-
0035672697
-
Comparison of intramuscular therapy with Erwinia asparaginase and asparaginase Medac: Pharmacokinetics, pharmacodynamics, formation of antibodies and influence on the coagulation system
-
Albertsen BK, Schroder H, Ingerslev J, et al. Comparison of intramuscular therapy with Erwinia asparaginase and asparaginase Medac: Pharmacokinetics, pharmacodynamics, formation of antibodies and influence on the coagulation system. Br J Haematol 2001;115:983-990.
-
(2001)
Br J Haematol
, vol.115
, pp. 983-990
-
-
Albertsen, B.K.1
Schroder, H.2
Ingerslev, J.3
-
22
-
-
0034796838
-
Monitoring of Erwinia asparaginase therapy in childhood ALL in the Nordic countries
-
Albertsen BK, Schroder H, Jakobsen P, et al. Monitoring of Erwinia asparaginase therapy in childhood ALL in the Nordic countries. Br J Clin Pharmacol 2001;52:433-437.
-
(2001)
Br J Clin Pharmacol
, vol.52
, pp. 433-437
-
-
Albertsen, B.K.1
Schroder, H.2
Jakobsen, P.3
-
23
-
-
0034791821
-
Pharmacokinetics of native Escherichia coli asparaginase (Asparaginase medac) and hypersensitivity reactions in ALL-BFM 95 reinduction treatment
-
Muller HJ, Beier R, Loning L, et al. Pharmacokinetics of native Escherichia coli asparaginase (Asparaginase medac) and hypersensitivity reactions in ALL-BFM 95 reinduction treatment. Br J Haematol 2001;114:794-799.
-
(2001)
Br J Haematol
, vol.114
, pp. 794-799
-
-
Muller, H.J.1
Beier, R.2
Loning, L.3
-
24
-
-
0035018209
-
Drug monitoring of low-dose PEG-asparaginase (Oncaspar) in children with relapsed acute lymphoblastic leukaemia
-
Vieira Pinheiro JP, Muller HJ, Schwabe D, et al. Drug monitoring of low-dose PEG-asparaginase (Oncaspar) in children with relapsed acute lymphoblastic leukaemia. Br J Haematol 2001;113:115-119.
-
(2001)
Br J Haematol
, vol.113
, pp. 115-119
-
-
Vieira Pinheiro, J.P.1
Muller, H.J.2
Schwabe, D.3
-
25
-
-
0037085747
-
A randomized comparison of native Escherichia coli asparaginase and polyethylene glycol conjugated asparaginase for treatment of children with newly diagnosed standard-risk acute lymphoblastic leukemia: A Children's Cancer Group study
-
Avramis VI, Sencer S, Periclou AP, et al. A randomized comparison of native Escherichia coli asparaginase and polyethylene glycol conjugated asparaginase for treatment of children with newly diagnosed standard-risk acute lymphoblastic leukemia: A Children's Cancer Group study. Blood 2002;99:1986-1994.
-
(2002)
Blood
, vol.99
, pp. 1986-1994
-
-
Avramis, V.I.1
Sencer, S.2
Periclou, A.P.3
-
26
-
-
0036163591
-
PEG-asparaginase (Oncaspar) 2500 U/m(2) BSA in reinduction and relapse treatment in the ALL/NHL-BFM protocols
-
Muller HJ, Beier R, da Palma JC, et al. PEG-asparaginase (Oncaspar) 2500 U/m(2) BSA in reinduction and relapse treatment in the ALL/NHL-BFM protocols. Cancer Chemother Pharmacol 2002;49:149-154.
-
(2002)
Cancer Chemother Pharmacol
, vol.49
, pp. 149-154
-
-
Muller, H.J.1
Beier, R.2
Da Palma, J.C.3
-
27
-
-
0026315680
-
Measurement of serum L-asparagine in the presence of L-asparaginase requires the presence of an L-asparaginase inhibitor
-
Asselin BL, Lorenson MY, Whitin JC, et al. Measurement of serum L-asparagine in the presence of L-asparaginase requires the presence of an L-asparaginase inhibitor. Cancer Res 1991;51:6568-6573.
-
(1991)
Cancer Res
, vol.51
, pp. 6568-6573
-
-
Asselin, B.L.1
Lorenson, M.Y.2
Whitin, J.C.3
-
28
-
-
0014735839
-
L-asparaginase activity in plasma and other biological fluids
-
Schwartz MK, Lash ED, Oettgen HF, et al. L-asparaginase activity in plasma and other biological fluids. Cancer 1970;25:244-252.
-
(1970)
Cancer
, vol.25
, pp. 244-252
-
-
Schwartz, M.K.1
Lash, E.D.2
Oettgen, H.F.3
-
29
-
-
0019778519
-
L-asparaginase pharmacokinetics and asparagine levels in cerebrospinal fluid of rhesus monkeys and humans
-
Riccardi R, Holcenberg JS, Glaubiger DL, et al. L-asparaginase pharmacokinetics and asparagine levels in cerebrospinal fluid of rhesus monkeys and humans. Cancer Res 1981;41:4554-4558.
-
(1981)
Cancer Res
, vol.41
, pp. 4554-4558
-
-
Riccardi, R.1
Holcenberg, J.S.2
Glaubiger, D.L.3
-
30
-
-
0034523201
-
Co-operative study group for childhood acute lymphoblastic leukemia (COALL): Long-term follow-up of trials 82, 85, 89 and 92
-
Harms DO, Janka-Schaub GE. Co-operative study group for childhood acute lymphoblastic leukemia (COALL): Long-term follow-up of trials 82, 85, 89 and 92. Leukemia 2000;14:2234-2239.
-
(2000)
Leukemia
, vol.14
, pp. 2234-2239
-
-
Harms, D.O.1
Janka-Schaub, G.E.2
-
31
-
-
0036807796
-
Analytical validation of a microplate reader-based method for the therapeutic drug monitoring of L-asparaginase in human serum
-
Lanvers C, Vieira Pinheiro JP, Hempel G, et al. Analytical validation of a microplate reader-based method for the therapeutic drug monitoring of L-asparaginase in human serum. Anal Biochem 2002;309:117-126.
-
(2002)
Anal Biochem
, vol.309
, pp. 117-126
-
-
Lanvers, C.1
Vieira Pinheiro, J.P.2
Hempel, G.3
-
32
-
-
0019215680
-
Rapid high-performance liquid chromatographic determination of amino acids in synaptosomal extracts
-
Lenda K, Svenneby G. Rapid high-performance liquid chromatographic determination of amino acids in synaptosomal extracts. J Chromatogr 1980;198:516-519.
-
(1980)
J Chromatogr
, vol.198
, pp. 516-519
-
-
Lenda, K.1
Svenneby, G.2
-
33
-
-
0034284267
-
Weekly polyethylene glycol conjugated L-asparaginase compared with biweekly dosing produces superior induction remission rates in childhood relapsed acute lymphoblastic leukemia: A Pediatric Oncology Group Study
-
Abshire TC, Pollock BH, Billett AL, et al. Weekly polyethylene glycol conjugated L-asparaginase compared with biweekly dosing produces superior induction remission rates in childhood relapsed acute lymphoblastic leukemia: A Pediatric Oncology Group Study. Blood 2000;96:1709-1715.
-
(2000)
Blood
, vol.96
, pp. 1709-1715
-
-
Abshire, T.C.1
Pollock, B.H.2
Billett, A.L.3
-
34
-
-
17744400282
-
Long-term results of three randomized trials (58831, 58832, 58881) in childhood acute lymphoblastic leukemia: A CLCG-EORTC report
-
Children Leukemia Cooperative Group
-
Vilmer E, Suciu S, Ferster A, et al. Long-term results of three randomized trials (58831, 58832, 58881) in childhood acute lymphoblastic leukemia: A CLCG-EORTC report. Children Leukemia Cooperative Group. Leukemia 2000;14:2257-2266.
-
(2000)
Leukemia
, vol.14
, pp. 2257-2266
-
-
Vilmer, E.1
Suciu, S.2
Ferster, A.3
-
35
-
-
0037089437
-
Comparison of Escherichia coli-asparaginase with Erwinia-asparaginase in the treatment of childhood lymphoid malignancies: Results of a randomized European Organisation for Research and Treatment of Cancer-Children's Leukemia Group phase 3 trial
-
Duval M, Suciu S, Ferster A, et al. Comparison of Escherichia coli-asparaginase with Erwinia-asparaginase in the treatment of childhood lymphoid malignancies: Results of a randomized European Organisation for Research and Treatment of Cancer-Children's Leukemia Group phase 3 trial. Blood 2002;99:2734-2739.
-
(2002)
Blood
, vol.99
, pp. 2734-2739
-
-
Duval, M.1
Suciu, S.2
Ferster, A.3
-
36
-
-
0024391865
-
Reference values for amino acids in cerebrospinal fluid of children determined using ion-exchange chromatography with fluorimetric detection
-
Gerrits GP, Trijbels FJ, Monnens LA, et al. Reference values for amino acids in cerebrospinal fluid of children determined using ion-exchange chromatography with fluorimetric detection. Clin Chim Acta 1989;182:271-280.
-
(1989)
Clin Chim Acta
, vol.182
, pp. 271-280
-
-
Gerrits, G.P.1
Trijbels, F.J.2
Monnens, L.A.3
-
37
-
-
0032945308
-
Cerebrospinal fluid asparagine concentrations after Escherichia coli asparaginase in children with acute lymphoblastic leukemia
-
Woo MH, Hak LJ, Storm MC, et al. Cerebrospinal fluid asparagine concentrations after Escherichia coli asparaginase in children with acute lymphoblastic leukemia. J Clin Oncol 1999;17:1568-1573.
-
(1999)
J Clin Oncol
, vol.17
, pp. 1568-1573
-
-
Woo, M.H.1
Hak, L.J.2
Storm, M.C.3
-
38
-
-
0014851427
-
Biochemical and pharmacological studies with asparaginase in man
-
Ohnuma T, Holland JF, Freeman A, et al. Biochemical and pharmacological studies with asparaginase in man. Cancer Res 1970;30:2297-2305.
-
(1970)
Cancer Res
, vol.30
, pp. 2297-2305
-
-
Ohnuma, T.1
Holland, J.F.2
Freeman, A.3
-
39
-
-
0029810891
-
L-Asparagine depletion in plasma and cerebro-spinal fluid of children with acute lymphoblastic leukemia during subsequent exposures to Erwinia L-asparaginase
-
Gentili D, Conter V, Rizzari C, et al. L-Asparagine depletion in plasma and cerebro-spinal fluid of children with acute lymphoblastic leukemia during subsequent exposures to Erwinia L-asparaginase. Ann Oncol 1996;7:725-730.
-
(1996)
Ann Oncol
, vol.7
, pp. 725-730
-
-
Gentili, D.1
Conter, V.2
Rizzari, C.3
-
40
-
-
4143063669
-
Asparaginase pharmacokinetics after intensive polyethylene glycol-conjugated L-asparaginase therapy for children with relapsed acute lymphoblastic leukemia
-
Hawkins DS, Park JR, Thomson BG, et al. Asparaginase pharmacokinetics after intensive polyethylene glycol-conjugated L-asparaginase therapy for children with relapsed acute lymphoblastic leukemia. Clin Cancer Res 2004;10:5335-5341.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 5335-5341
-
-
Hawkins, D.S.1
Park, J.R.2
Thomson, B.G.3
-
41
-
-
0242475199
-
Lack of asparagine depletion in the cerebrospinal fluid after one intravenous dose of PEG-asparaginase: A window study at initial diagnosis of childhood ALL
-
Appel IM, Pinheiro JP, den Boer ML, et al. Lack of asparagine depletion in the cerebrospinal fluid after one intravenous dose of PEG-asparaginase: A window study at initial diagnosis of childhood ALL. Leukemia 2003;17:2254-2256.
-
(2003)
Leukemia
, vol.17
, pp. 2254-2256
-
-
Appel, I.M.1
Pinheiro, J.P.2
Den Boer, M.L.3
-
42
-
-
75449125982
-
Evidence that the L-asparaginase of guinea pig serum is responsible for its antilymphoma effects. II. Lymphoma 6C3HED cells cultured in a medium devoid of L-asparagine lose their susceptibility to the effects of guinea pig serum in vivo
-
Broome JD. Evidence that the L-asparaginase of guinea pig serum is responsible for its antilymphoma effects. II. Lymphoma 6C3HED cells cultured in a medium devoid of L-asparagine lose their susceptibility to the effects of guinea pig serum in vivo. J Exp Med 1963;118:121-148.
-
(1963)
J Exp Med
, vol.118
, pp. 121-148
-
-
Broome, J.D.1
|